Dr Dina Kronhaus University positionSenior Research Associate DepartmentsFaculty of Music and Computer Laboratory InstitutesCambridge Computational Biology Institute (CCBI) and Wolfson Brain Imaging Centre Research ThemesInterestsMy research is focused on studying connectivity and neural re-organisation, in the human brain, using theoretical modelling techniques to complement analysis of experimental data. I aim to identify overlapping yet distinct neural circuits implicated in processes of memory, emotion and cognitive control. I use computational models to study dynamics of networks and predict how experimental manipulation of network constituents affects overall behaviour. Research Focus
EquipmentComputational modelling Magnetic resonance imaging (MRI) Positron Emission Tomography (PET) Collaborators
Associated News ItemsKey publicationsKronhaus DM et al (2006), “Stroop performance in bipolar disorder: further evidence for abnormalities in the ventral prefrontal cortex” Bipolar Disord 8(1):28-39 Kronhaus DM, Willshaw DJ (2006), “The cingulate as a catalyst region for global dysfunction: a dynamical modelling paradigm” Cereb Cortex 16(8):1212-24 Details Publications2014Stan AD, Schirda CV, Bertocci MA, Bebko GM, Kronhaus DM, Aslam HA, LaBarbara EJ, Tanase C, Lockovich JC, Pollock MH, Stiffler RS, Phillips ML (2014), “Glutamate and GABA contributions to medial prefrontal cortical activity to emotion: Implications for mood disorders.” Psychiatry Res Details 2013Fournier JC, Keener MT, Almeida J, Kronhaus DM, Phillips ML (2013), “Amygdala and whole-brain activity to emotional faces distinguishes major depressive disorder and bipolar disorder.” Bipolar Disord 15(7):741-52 Details Fournier JC, Keener MT, Mullin BC, Hafeman DM, Labarbara EJ, Stiffler RS, Almeida J, Kronhaus DM, Frank E, Phillips ML (2013), “Heterogeneity of amygdala response in major depressive disorder: the impact of lifetime subthreshold mania.” Psychol Med 43(2):293-302 Details Herringa RJ, Phillips ML, Fournier JC, Kronhaus DM, Germain A (2013), “Childhood and adult trauma both correlate with dorsal anterior cingulate activation to threat in combat veterans.” Psychol Med 43(7):1533-42 Details 2012Keener MT, Fournier JC, Mullin BC, Kronhaus D, Perlman SB, LaBarbara E, Almeida JC, Phillips ML (2012), “Dissociable patterns of medial prefrontal and amygdala activity to face identity versus emotion in bipolar disorder.” Psychol Med 42(9):1913-24 Details Perlman SB, Almeida JR, Kronhaus DM, Versace A, Labarbara EJ, Klein CR, Phillips ML (2012), “Amygdala activity and prefrontal cortex-amygdala effective connectivity to emerging emotional faces distinguish remitted and depressed mood states in bipolar disorder.” Bipolar Disord 14(2):162-74 Details Radua J, Mataix-Cols D, Phillips ML, El-Hage W, Kronhaus DM, Cardoner N, Surguladze S (2012), “A new meta-analytic method for neuroimaging studies that combines reported peak coordinates and statistical parametric maps.” Eur Psychiatry 27(8):605-11 Details Surguladze SA, Radua J, El-Hage W, Gohier B, Sato JR, Kronhaus DM, Proitsi P, Powell J, Phillips ML (2012), “Interaction of catechol O-methyltransferase and serotonin transporter genes modulates effective connectivity in a facial emotion-processing circuitry.” Transl Psychiatry 2:e70 Details 2011Almeida JR, Kronhaus DM, Sibille EL, Langenecker SA, Versace A, Labarbara EJ, Phillips ML (2011), “Abnormal left-sided orbitomedial prefrontal cortical-amygdala connectivity during happy and fear face processing: a potential neural mechanism of female MDD.” Front Psychiatry 2:69 Details 2009Ladouceur CD, Silk JS, Dahl RE, Ostapenko L, Kronhaus DM, Phillips ML (2009), “Fearful faces influence attentional control processes in anxious youth and adults.” Emotion 9(6):855-64 Details 2006Kronhaus DM, Lawrence NS, Williams AM, Frangou S, Brammer MJ, Williams SC, Andrew CM, Phillips ML (2006), “Stroop performance in bipolar disorder: further evidence for abnormalities in the ventral prefrontal cortex.” Bipolar Disord 8(1):28-39 Details |