Dr Benjamin Perry

University position

Clinical Lecturer


Department of Psychiatry



Home page


Research Theme

Clinical and Veterinary Neuroscience


I am a Clinical Lecturer in the Department of Psychiatry, and a Higher Trainee in General Psychiatry in Cambridgeshire and Peterborough NHS Foundation Trust. I recently completed an NIHR Doctoral Research Fellowship in the Department.

I'm interested in the associations of cardiometabolic and mental disorders, primarily schizophrenia and depression. I'm particularly interested in prognosis research and risk prediction, and during my PhD developed the Psychosis Metabolic Risk Calculator (PsyMetRiC) - a cardiometabolic risk prediction algorithm for young people with psychosis.

In addition, through the use of population-level and genetic data, my work has sought to explore shared biological mechanisms for comorbid cardiometabolic and mental disorders.

Research Focus


cardiometabolic disorders



risk prediction

prognosis research

Clinical conditions

Cardiometabolic Disorders

Depressive disorders




Cross-sectional and cohort studies

Prognosis Research; Risk Prediction; Algorithm Development



Simon Griffin

Peter Jones

Graham Murray

Nicholas Wareham

United Kingdom

Golam Khandaker Web: http://golam.khandaker@bristol.ac.uk

Rachel Upthegrove Web: https://www.birmingham.ac.uk/staff/p...

Stan Zammit Web: http://zammitS@cardiff.ac.uk

Associated News Items

    Key publications

    Perry BI, Burgess S, Jones HJ, Zammit S, Upthegrove R, Mason AM, Day FR, Langenberg C, Wareham NJ, Jones PB, Khandaker GM. (2021), “The potential shared role of inflammation in insulin resistance and schizophrenia: A bidirectional two-sample mendelian randomization study” PLOS Medicine

    Perry BI, Osimo EF, Upthegrove R, Mallikarjun PK, Yorke J, Stochl J, Perez J, Zammit S, Howes O, Jones PB, Khandaker GM. (2021), “Development and external validation of the Psychosis Metabolic Risk Calculator (PsyMetRiC): a cardiometabolic risk prediction algorithm for young people with psychosis” The Lancet Psychiatry

    Perry BI, Stochl J, Upthegrove R, Zammit S, Wareham NJ, Langenberg C, Winpenny E, Dunger D, Jones PB, Khandaker GM (2021), “Longitudinal trends in childhood insulin levels and body mass index and associations with risks of psychosis and depression in young adults” JAMA Psychiatry

    Perry BI, McIntosh G, Weich S, Singh SP, Rees K. (2016), “The association between first-episode psychosis and abnormal glycaemic control: systematic review and meta-analysis” The Lancet Psychiatry



    Osimo EF, Baxter L, Stochl J, Perry BI, Metcalf SA, Kunutsor SK, Laukkanen JA, Wium-Andersen MK, Jones PB, Khandaker GM (2021), “Longitudinal association between CRP levels and risk of psychosis: a meta-analysis of population-based cohort studies” npj Schizophrenia

    Perry BI, Osimo EF, Khandaker GM (2021), “Risk Prediction in Psychosis: Progress Made and Challenges Ahead” Biological Psychiatry

    Perry BI, Upthegrove R, Kappelmann N, Jones PB, Burgess S, Khandaker GM (2021), “Associations of immunological proteins/traits with schizophrenia, major depression and bipolar disorder: A bi-directional two-sample mendelian randomization study” Brain, Behavior & Immunity

    Perry BI, Zammit S, Jones PB, Khandaker GM. (2021), “Childhood inflammatory markers and risks for psychosis and depression at age 24: Examination of temporality and specificity of association in a population-based prospective birth cohort” Schizophrenia Research


    Perry BI, Jones HJ, Richardson TG, Zammit S, Wareham NJ, Lewis G, Jones PB, Khandaker GM. (2020), “Common mechanisms for type 2 diabetes and psychosis: Findings from a prospective birth cohort” Schizophrenia Research

    Perry BI, Oltean BP, Jones PB, Khandaker GM (2020), “Cardiometabolic risk in young adults with depression and evidence of inflammation: A birth cohort study” Psychoneuroendocrinology

    Perry BI, Upthegrove R, Crawford O, Jang S, Lau E, McGill I, Carver E, Jones PB, Khandaker GM (2020), “Cardiometabolic risk prediction algorithms for young people with psychosis: a systematic review and exploratory analysis” Acta Psychiatrica Scandinavica


    Perry BI, Khandaker GM, Marwaha S, Thompson A, Zammit S, Singh SP, Upthegrove R (2019), “Insulin resistance and obesity, and their association with depression in relatively young people: findings from a large UK birth cohort” Psychological Medicine


    BI Perry, SE Cooray, J Mendis, K Purandare, A Wijeratne, et al. (2018), “Problem behaviours and psychotropic medication use in intellectual disability: a multinational cross?sectional survey” Journal of Intellectual Disability Research

    BI Perry, SS Singh (2018), “Letter to the Editor: Lipid profile disturbances in antipsychotic-naive patients with first-episode non-affective psychosis.” Schizophrenia Research

    Perry BI, Upthegrove, R, Thompson, A, Marwaha, S, Zammit, S, Khandaker, GM (2018), “Relationships between dysglycaemia, immune activation and psychotic experiences: findings from the U.K. ALSPAC birth cohort” Schizophrenia Bulletin

    Rowland T, Perry BI, Upthegrove R, Barnes N, Chatterjee J, Gallacher D, Marwaha S. (2018), “Neurotrophins, cytokines, oxidative stress mediators and mood state in bipolar disorder: systematic review and meta-analyses” British Journal of Psychiatry


    BI Perry, K Meehan, AK Jainer (2017), “Assessing the second-hand effects of a new no-smoking policy in an acute mental health trust” British Journal of Psychiatry Bulletin

    BI Perry, SS Singh (2017), “On psychiatry unlocked.” Lancet Psychiatry

    Perry BI, Salimkumar D, Green D, Meakin A, Gibson A, Mahajan D, Tahir T, Singh, SP. (2017), “Associated illness severity in schizophrenia and diabetes mellitus: a systematic review” Psychiatry Research