Dr Arkoprovo Paul![]() University positionResearch Associate DepartmentsDepartment of Clinical Neurosciences InstitutesMRC Cambridge Stem Cell Institute Home pagehttp://www.linkedin.com/in/ap86... (personal home page) Research ThemesInterestsI am investigating functional phenotypes of human induced pluripotent stem cell (iPSC) derived Neurons, Astrocytes and Microglia generated using CRISPR/Cas9 genome editing tools and forward reprogramming technologies. My current research is focussed on understanding neuron-glia interactions in isogenic disease models of neurodevelopment and neurodegeneration using network electrophysiology and single cell transcriptomics; with the aim to establish an optimised platform for discovery and therapeutics. Research Focus
EquipmentBioinformatics Calcium imaging Cell culture Computational modelling Confocal microscopy Electrophysiological recording techniques Enzyme assays Fluorescence microscopy Gene editing Immunohistochemistry Microscopy Multi-electrode arrays Single cell transcriptomics Western blotting Collaborators
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