Dr Andrew Osborne

University Position

Research Associate

Interests

My research interest lies in how stem cells offer neuroprotection to retinal ganglion cells with particular interest to how secreted factors prevent visual loss. My project focuses on how platelet-derived growth factor (PDGF) can reduce retinal damage in human and animal models of glaucoma and its implications as a future therapy.

Key Publications

Protrudin functions from the endoplasmic reticulum to support axon regeneration in the adult CNS.

DOI: http://doi.org/10.1038/s41467-020-19436-y
Journal: Nat Commun
E-pub date: 5 Nov 2020
Authors: V Petrova, CS Pearson, J Ching, JR Tribble, AG Solano, Y Yang, FM Love, RJ Watt, A Osborne, E Reid, PA Williams, KR Martin, HM Geller, R Eva, JW Fawcett

PI 3-kinase delta enhances axonal PIP3 to support axon regeneration in the adult CNS.

DOI: http://doi.org/10.15252/emmm.201911674
Journal: EMBO Mol Med
E-pub date: 7 Aug 2020
Authors: B Nieuwenhuis, AC Barber, RS Evans, CS Pearson, J Fuchs, AR MacQueen, S van Erp, B Haenzi, LA Hulshof, A Osborne, R Conceicao, TZ Khatib, SS Deshpande, J Cave, C Ffrench-Constant, PD Smith, K Okkenhaug, BJ Eickholt, KR Martin, JW Fawcett, R Eva