Dr Andrew Osborne

University position

Research Associate

Departments

Department of Clinical Neurosciences

Institutes

Cambridge Centre for Brain Repair

Email

ao361@cam.ac.uk

Home page

http://www.brc.cam.ac.uk/

Research Theme

Cellular and Molecular Neuroscience

The Cambridge Neuroscience Community

Interests

My research interest lies in how stem cells offer neuroprotection to retinal ganglion cells with particular interest to how secreted factors prevent visual loss.

My project focuses on how platelet-derived growth factor (PDGF) can reduce retinal damage in human and animal models of glaucoma and its implications as a future therapy.

Research Focus

Keywords

Glaucoma

Neuroprotection

Survival

Growth Factors

Stem Cells

Clinical conditions

Glaucoma

Equipment

Cell culture

Collaborators

No collaborators listed

Associated News Items

Gene therapy technique shows potential for repairing damage caused by glaucoma and dementia

Publications

2014

Johnson TV, Dekorver NW, Levasseur VA, Osborne A, Tassoni A, Lorber B, Heller JP, Villasmil R, Bull ND, Martin KR, Tomarev SI (2014), “Identification of retinal ganglion cell neuroprotection conferred by platelet-derived growth factor through analysis of the mesenchymal stem cell secretome.” Brain 137(Pt 2):503-19 Details

2011

Niyadurupola N, Sidaway P, Osborne A, Broadway DC, Sanderson J (2011), “The development of human organotypic retinal cultures (HORCs) to study retinal neurodegeneration.” Br J Ophthalmol 95(5):720-6 Details