Anne Manktelow University positionPhD student DepartmentsInstitutesHome pagehttp://www.medschl.cam.ac.uk/anaesth... Research ThemeInterestsI work part-time in the Division of Anaesthesia as a Research Assistant conducting the follow-up studies with patients recovering from traumatic brain injury (including MRI scanning and neuropsychological testing). I am also undertaking a part-time PhD within the department. The focus of my research will be the examination of the functional connectivity within the Default Mode Network post traumatic brain injury using resting state fMRI. We are comparing the alterations in this key resting state network between healthy controls and patients recovering from severe traumatic brain injury. We want to investigate how the brain compensates for loss of function due to the damage inflicted by the injury and explore the evidence for neural plasticity in the functional and structural connectivity analysis conducted on the TBI patients. Research Focus
EquipmentNo equipment indicated Collaborators
Associated News ItemsPublications2013Newcombe VF, Williams GB, Outtrim JG, Chatfield D, Gulia Abate M, Geeraerts T, Manktelow A, Room H, Mariappen L, Hutchinson PJ, Coles JP, Menon DK (2013), “Microstructural basis of contusion expansion in traumatic brain injury: insights from diffusion tensor imaging.” J Cereb Blood Flow Metab 33(6):855-62 Details 2012Sorrentino E, Diedler J, Kasprowicz M, Budohoski KP, Haubrich C, Smielewski P, Outtrim JG, Manktelow A, Hutchinson PJ, Pickard JD, Menon DK, Czosnyka M (2012), “Critical thresholds for cerebrovascular reactivity after traumatic brain injury.” Neurocrit Care 16(2):258-66 Details 2011Newcombe V, Chatfield D, Outtrim J, Vowler S, Manktelow A, Cross J, Scoffings D, Coleman M, Hutchinson P, Coles J, Carpenter TA, Pickard J, Williams G, Menon D (2011), “Mapping traumatic axonal injury using diffusion tensor imaging: correlations with functional outcome.” PLoS One 6(5):e19214 Details Newcombe VF, Outtrim JG, Chatfield DA, Manktelow A, Hutchinson PJ, Coles JP, Williams GB, Sahakian BJ, Menon DK (2011), “Parcellating the neuroanatomical basis of impaired decision-making in traumatic brain injury.” Brain 134(Pt 3):759-68 Details 2010Zweifel C, Castellani G, Czosnyka M, Helmy A, Manktelow A, Carrera E, Brady KM, Hutchinson PJ, Menon DK, Pickard JD, Smielewski P (2010), “Noninvasive monitoring of cerebrovascular reactivity with near infrared spectroscopy in head-injured patients.” J Neurotrauma 27(11):1951-8 Details |