Aicha Massrali

Aicha  Massrali

University position

PhD student
Supervised by Simon Baron-Cohen

Departments

Department of Psychiatry

Institutes

Autism Research Centre

Email

am2366@cam.ac.uk

Home page

https://www.autismresearchcentre.com/people_...

Research Themes

Cellular and Molecular Neuroscience

Developmental Neuroscience

Interests

I am studying atypical neuronal development in the autism brain using patient-derived induced pluripotent stem cell (iPSC). The use of iPSC combined with genome editing technologies allows me to investigate the role of an autism high risk gene (Neurexin I) and its role in synaptic transmission in iPSC-derived induced neurons. I am also interested in the contribution of steroid hormones to differential synaptic gene expression during brain development in autism.

Research Focus

Keywords

Methylation

iPSC

Autism

testosterone

neuronal development

Clinical conditions

Autism

Equipment

Calcium imaging

Cell culture

Confocal microscopy

Electrophysiological recording techniques

Fluorescence microscopy

Genome editing (CRISPR-Cas9)

Whole cell patch clamp

Collaborators

Cambridge

Mark Kotter

United Kingdom

Jack Price Web: http://www.kcl.ac.uk/ioppn/d...

International

Deepak Srivastava Web: https://kclpure.kcl.ac.uk/portal/...

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