Dr Alekhya Mandali
I am an engineer turned computational neuroscientist with a research focus on building mathematical models and applying computational techniques to study the pathophysiology of various neurological and psychiatric conditions such as Parkinson's disease, OCD and addiction. Specifically to understand the effect of various therapeutic techniques such as pharmaceutical medications and deep brain stimulation
During my PhD, I have built spiking network models and studied the effect of dopaminergic medication and subthalamic nucleus(STN) stimulation on cognitive functions of Parkinson's disease
At Dr.Voon's lab, I work on integrating the experimental and computational methodologies for a better understanding of compulsive and impulsive behaviours in OCD and addiction. I am also interested in studying the computational role of STN in decision making in health and disease conditions
Associated News Items
Mandali A, Weidacker K, Kim SG, Voon V (2019), “ The ease and sureness of a decision: evidence accumulation of conflict and uncertainty” Brain Volume 142, Issue 5, Pages 1471–1482
Mandali A, Rengaswamy M, Chakravarthy VS, Moustafa AA. (2015), “A spiking Basal Ganglia model of synchrony, exploration and decision making. ” Frontiers in Neuroscience. 9:191.