Mr Andrea Luppi


University position

PhD student
Supervised by Dr Emmanuel Stamatakis

Departments

Department of Clinical Neurosciences

Institutes

Division of Anaesthesia

Email

al857@cam.ac.uk

Home page

http://anaesthetics.medschl.cam.ac.uk/

Research Themes

Cognitive and Behavioural Neuroscience

Systems and Computational Neuroscience

Interests

Coming from a background in philosophy and cognitive science, I am interested in the relation between mind and (grey) matter. Specifically, my PhD work aims to characterise how the capacity for cognition and consciousness arises from the complex interactions between brain systems, viewed as a dynamic network. To this end, I combine tools from information theory, network science and whole-brain computational modelling to study the cortical dynamics and connectivity of the brain across multiple scales and modalities (functional MRI, DTI) throughout a variety of states of altered consciousness – such as anaesthesia and disorders of consciousness, but also sleep and psychedelics. Ultimately, I aim to develop a landscape of altered states of consciousness, and a unified theoretical understanding of how consciousness is lost, and how we can promote its recovery in patients.

Research Focus

Keywords

consciousness

fMRI

networks

complexity

information theory

Clinical conditions

Stroke

Traumatic brain injury

Equipment

Computational modelling

Magnetic resonance imaging (MRI)

Collaborators

Cambridge

Judith Allanson

Dan Bor

Pedro Mediano

David Menon

John Pickard

Guy Williams

United Kingdom

Selen Atasoy Web: https://www.psych.ox.ac.uk/

Robin Carhart-Harris Web: https://www.imperial.ac.uk/psyched...

Morten Kringelbach Web: https://www.psych.ox.ac.uk/

Jakub Vohryzek Web: https://www.psych.ox.ac.uk/

International

Lorina Naci Web: https://www.lorinanaci.org/

Adrian Owen Web: https://owenlab.uwo.ca/

Associated News Items


Key publications

TF Varley†, A Luppi†, I Pappas, R Adapa, A Owen, L Naci, DK Menon, EA Stamatakis (2020), “Consciousness & Brain Functional Complexity in Propofol Anaesthesia” Sci Rep 10, 1018

AI Luppi, MM Craig, I Pappas, P Finoia, GB Williams, J Allanson, JD Pickard, AM Owen, L Naci, DK Menon & EA Stamatakis (2019), “Consciousness-specific dynamic interactions of brain integration and functional diversity. Nature Communications” Nat Comm 10(1):4616