Dr Fardad Afshari


I am interested in studying astrocyte biology in the context of gliosis following CNS injury and tumour cell invasion.

Research Focus



Glial scar


Schwann cells


Clinical conditions



Spinal cord injury

Traumatic brain injury


Behavioural analysis

Cell adhesion assays

Cell culture

Cell migration assays

Confocal microscopy




No collaborators listed

Associated News Items



    Afshari FT, Fitzgerald JJ, Higgins JN, Garnett MR, Fernandes HM, Santarius T (2013), “Diffuse cerebral vasospasm following resection of a hypoglossal schwannoma in a child.” Br J Neurosurg Details

    Kolias AG, Bulters DO, Cowie CJ, Wilson MH, Afshari FT, Helmy A, Broughton E, Joannides AJ, Zebian B, Harrisson SE, Hill CS, Ahmed AI, Barone DG, Thakur B, McMahon CJ, Adlam DM, Bentley RP, Tolias CM, Mitchell PM, Whitfield PC, Critchley GR, Belli A, Brennan PM, Hutchinson PJ, British Neurosurgical Trainee Research Collaborative, British Neurotrauma Group, UKCRR Collaborative Group (2013), “Proposal for establishment of the UK Cranial Reconstruction Registry (UKCRR).” Br J Neurosurg Details

    Kolias AG, Jones TL, Cowie CJ, Coulter IC, Afshari FT, Tarnaris A, Nelson RJ, Gray WP, Hutchinson PJ, Brennan PM (2013), “A report from the inaugural meeting of the British Neurosurgical Trainee Research Collaborative held in the Royal College of Surgeons of England, 19 October 2012.” Br J Neurosurg Details


    Afshari FT, Fawcett JW (2012), “An in vitro assay to examine oligodendrocyte precursor cell migration on astrocytes.” Methods Mol Biol 814:393-9 Details

    Afshari FT, Fawcett JW (2012), “Astrocyte-Schwann-cell coculture systems.” Methods Mol Biol 814:381-91 Details

    Santarius T, Dakoji S, Afshari FT, Raymond FL, Firth HV, Fernandes HM, Garnett MR (2012), “Isolated hypoglossal schwannoma in a 9-year-old child.” J Neurosurg Pediatr 10(2):130-3 Details


    Afshari FT, Kwok JC, Fawcett JW (2011), “Analysis of Schwann-astrocyte interactions using in vitro assays.” J Vis Exp (47) Details


    Afshari FT, Kwok JC, Andrews MR, Blits B, Martin KR, Faissner A, Ffrench-Constant C, Fawcett JW (2010), “Integrin activation or alpha 9 expression allows retinal pigmented epithelial cell adhesion on Bruch's membrane in wet age-related macular degeneration.” Brain 133(Pt 2):448-64 Details

    Afshari FT, Kwok JC, Fawcett JW (2010), “Astrocyte-produced ephrins inhibit schwann cell migration via VAV2 signaling.” J Neurosci 30(12):4246-55 Details

    Afshari FT, Kwok JC, White L, Fawcett JW (2010), “Schwann cell migration is integrin-dependent and inhibited by astrocyte-produced aggrecan.” Glia 58(7):857-69 Details


    Afshari FT, Fawcett JW (2009), “Improving RPE adhesion to Bruch's membrane.” Eye (Lond) 23(10):1890-3 Details

    Afshari FT, Kappagantula S, Fawcett JW (2009), “Extrinsic and intrinsic factors controlling axonal regeneration after spinal cord injury.” Expert Rev Mol Med 11:e37 Details


    Kwok JC, Afshari F, García-Alías G, Fawcett JW (2008), “Proteoglycans in the central nervous system: plasticity, regeneration and their stimulation with chondroitinase ABC.” Restor Neurol Neurosci 26(2-3):131-45 Details