Dr Andrew Dean


Interest in: i) Genetically-determined and developmentally acquired disorders of the central and peripheral nervous system and muscle, encompassing neuropathy, myopathy, dystrophy, neuropathy, malformation, epilepsy and mental retardation; ii) structural influences on function; iii) radiological / histopathological correlation

Research Focus





inherited disease


Clinical conditions


Autoimmune diseases

Birth defects

Cerebrovascular disorders

Childhood disorders



Genetic disorders







Maxwell Damian

United Kingdom

Paul Griffiths Web: http://www.sheffield.ac.uk

Associated News Items

    Key publications

    LAX NZ, ALSTON CL, SCHON K, PARK S-M, KRISHNAKUMAR D, HE L, FALKOUS G, OGILVY-STUART-A, LEES C, KING RH, HARGREAVES I, BROWN G, McFARLAND R, DEAN AF, TAYLOR RW (2015), “Neuropathological characterisation of novel RARS2 mutations in two siblings with pontocerebellar hypoplasia, cardiomyopathy and hydrops fetalis associated with severe multi-system respiratory chain deficiency” J Neuropathol Expt Neurol 76: 688-703

    BENNETT H, MOK HP, GKRANIA-KLOTSAS E, TSAI IJ, STANLEY EJ, ANTOUN,COGLAN A, HARSHA B, TRAINI A, RIBEIRO DM, STEWINBASS S, LUCAS SB, ALLINSON KSJ, PRICE SJ, SANTARIUS TS, CARMICHAEL AJ, CHIODINI PL, HOLROYD N, DEAN AF, BERRIMAN M (2014), “The genome of the sparganosis tapeworm Spirometra erinaceieuropaei isolated from the biopsy of a migrating brain lesion ” Genome Research 15: 510

    JARVIS DA, ARMITAGE P, DEAN AF, GRIFFITHS PD (2014), “Surface reconstructions of fetal brain abnormalities using ultrafast steady state 3D acquisitions. ” Clin Radiol 69: 1084-1091

    LAX NZ, GNANAPAVAN S, DOWSON SJ, ALSTON CL, HE L, POLVIKOVSKI, T, JAROS E, O'DONOVAN DG, YARHAM JW, TURNBULL DM, DEAN AF and TAYLOR RW (2013), “Early-onset cataracts, spastic paraparesis, and ataxia due to a novel mitochondrial tRNAGlu (MT-TE) gene mutation causing severe complex I deficiency: a clinical, molecular and neuropathological study ” J Neuropathol Expt Neurol 72: 164-175

    Dean AF, Whitby EH (2007), “The contribution of antenatal MR imaging to diagnostic neuropathology” Curr Diagn Pathol 13:171-9

    Rezaie P, Dean AF, et al (2005), “ Microglia in the cerebral wall of the human telecephalon at second trimester” Cerebral Cortex 15:938-49

    Batchelor PG ., Dean AF (2002), “Measures of folding applied to the human brain” IEEE Trans Med Imag 21:953-965