Dr Alejandro Carnicer-Lombarte

Interests

Neural interfaces allow for the formation of connections between the nervous system and external devices, and hold great potential in both the clinic and basic research. Though traditionally electrical in nature, recent advance in microfabrication techniques and material sciences have allowed for the development of multimodal neural probes – combining modalities such as electrophysiology, drug delivery, and chemical sensing.

Our lab is currently developing implantable neural probes capable of combined eletrophysiological recordings and sensing of metabolites such as glucose and lactate. My current work involves the in vivo application of these devices in acute and chronic brain implantation models, aimed at the treatment of neurological conditions such as epilepsy.

Endoneurial fibroblast-like cells cultured on stiff substrates expressing alpha smooth muscle actin (green).
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Research Focus

Equipment

Behavioural analysis

Electrophysiological recording techniques

Field potential recording

Immunohistochemistry