Dr Stacey Anne Gould University positionResearch Associate DepartmentsDepartment of Clinical Neurosciences InstitutesCambridge Centre for Brain Repair Home pagehttps://www.researchgate.net/profile... (personal home page) Research ThemesInterestsI am currently exploring ways to target programmed axon death for therapeutic effect. I study the role of SARM1 activation after a range of physical and neurotoxic triggers, and how subsequent axon degeneration can be prevented using compounds with therapeutic potential. My earlier work in behavioural neuropharmacology focussed on peripheral mechanisms of pain generation and ways to improve preclinical predictability of analgesic efficacy in spontaneous pain assays. Research Focus
EquipmentBehavioural analysis Cell culture Enzyme assays Fluorescence microscopy Immunohistochemistry Microscopy Neuropsychological testing CollaboratorsNo collaborators listed Associated News ItemsPublicationsin pressGould SA, White M, Wilbrey AL, Pór E, Coleman MP, Adalbert R (in press), “Protection against oxaliplatin-induced mechanical and thermal hypersensitivity in Sarm1-/- mice.” Exp Neurol. 338:113607 2018Adalbert R, Milde S, Durrant C, Ando K, Stygelbout V, Yilmaz Z, Gould S, Brion JP, Coleman MP (2018), “ Interaction between a MAPT variant causing frontotemporal dementia and mutant APP affects axonal transport.” Neurobiol Aging 68:68-75 Rutten K, Gould SA, Bryden L, Doods H, Christoph T, Pekcec A (2018), “ Standard analgesics reverse burrowing deficits in a rat CCI model of neuropathic pain, but not in models of type 1 and type 2 diabetes-induced neuropathic pain” Behav Brain Res 350:129-138 2015Gould SA, Doods H, Lamla T, Pekcec A (2015), “Pharmacological characterization of intraplantar Complete Freund's Adjuvant-induced burrowing deficits ” Behav Brain Res 301:142-51 |