George Gibbons

University Position

Research Associate

Interests

I am currently a Research Associate working on developing novel human stem cell derived organoid models to explore disease, injury, and development. Using this platform, I hope to further elucidate novel human specific mechanisms and validate previous animal findings.

Key Publications

Human ALS/FTD brain organoid slice cultures display distinct early astrocyte and targetable neuronal pathology.

DOI: http://doi.org/10.1038/s41593-021-00923-4
Journal: Nat Neurosci
E-pub date: 1 Nov 2021
Authors: K Szebényi, LMD Wenger, Y Sun, AWE Dunn, CA Limegrover, GM Gibbons, E Conci, O Paulsen, SB Mierau, G Balmus, A Lakatos

Cerebral organoids at the air-liquid interface generate diverse nerve tracts with functional output.

DOI: http://doi.org/10.1038/s41593-019-0350-2
Journal: Nat Neurosci
E-pub date: 1 Apr 2019
Authors: SL Giandomenico, SB Mierau, GM Gibbons, LMD Wenger, L Masullo, T Sit, M Sutcliffe, J Boulanger, M Tripodi, E Derivery, O Paulsen, A Lakatos, MA Lancaster

A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models.

DOI: http://doi.org/10.1038/s41467-017-01283-z
Journal: Nat Commun
E-pub date: 27 Oct 2017
Authors: GE Tyzack, CE Hall, CR Sibley, T Cymes, S Forostyak, G Carlino, IF Meyer, G Schiavo, S-C Zhang, GM Gibbons, J Newcombe, R Patani, A Lakatos