Cellular & Molecular
The study of the behaviour of neurons at the cellular and molecular level has a long and distinguished tradition in Cambridge. Work on the cellular basis of sensation, developmental neurobiology, cell signalling, ion channels, neural degeneration and repair, and more integrative aspects of nervous system function are all strong areas in the School. Research spans a diverse spectrum from molecular signalling to neuroendocrinology to sensory and motor systems, with techniques used ranging from biochemical, single-cell recording and behavioural studies to large-scale computational methods. There are particular strengths in research on synaptic transmission, local network properties and sensory transduction, as well as a wealth of expertise at the Laboratory for Molecular Biology and the Sanger Institute.
Principal investigators
Dr Sabine Bahn
We are conducting an extensive research programme to define the molecular basis of schizophrenia and bipolar affective disorder. The internationally recognised scientific team has received the second largest award ever from the Stanley Medical Res...
Dr Roger Barker
I work on: Clinical aspects of Parkinson's and Huntington's disease including the study of disease heterogeneity using cognitive testing, functional imaging and genetic biomarkers. Examining the value of different biomarkers to assess disease onse...
Professor Eric Barnard
We earlier cloned the first GABA-A receptor subunits, the basis of the CNS major inhibitory pathways.We found these vary by their use of different GABA-A subtypes , by combinations drawn from 19 subunits.We have recently analysed their 19 ge...
Dr Howard Baylis
We are investigating the functions of genes involved in Alzheimer’s disease using C. elegans. We have focussed on presenilin genes as presenilin mutations in human cause familial Alzheimer’s disease. We aim to address the mechanism by which presen...
Dr Anne Bertolotti
Cellular aspects of protein misfolding in neurodegenerative diseases Neurodegenerative diseases characterized by accumulation of misfolded proteins are late-onset, implying that the proteins responsible for these diseases cause cellular dysfunctio...
Dr Brian Billups
My lab is interested in processes that modulate synaptic transmission. Using direct electrophysiological recordings from pre and postsynaptic cells in brain slices, combined with fluorescent ion imaging, we investigate release and recycling of ne...
Professor Andrea Brand FRS FMedSci
Discovering how stem cells are maintained in a multipotent state and how their progeny differentiate into distinct cellular fates is a key step in the therapeutic use of stem cells to repair tissues after damage or disease. We are investigating th...
Dr Sarah Bray
We are interested in understanding the signalling pathways that co-ordinate the decisions made by cells during development. The ultimate fate of a cell is dictated in part by its heredity and in part through interactions with neighbouring cells. O...
Professor Kevin Brindle
We have developed non-invasive magnetic resonance imaging (MRI) techniques that enable us to track labelled cells that have been implanted in the CNS. This work has been conducted in collaboration with Robin Franklin. In addition we are developi...
Dr Guy Brown
We are interested in the mechanisms of inflammatory neurodegeneration in the brain. We have been using cultures of neurons and glia to investigate how microglia become activated by inflammatory stimuli (such as cytokines, LPS, LTA, prions and bet...
Dr Raymond Bujdoso
Prion diseases such as scrapie of sheep and goats, BSE of cattle and CJD of humans are transmissible neurodegenerative diseases. The research of our prion group is concerned with providing knowledge to try and answer some of the important question...
Professor Malcolm Burrows
I work on the properties of neurons and the circuits they form to understand how they control behaviour. 1. Motor control. How do nonspiking local interneurons organise motor neurons to generate limb movements? How do spiking interneurons pro...
Dr Philip Buttery
We work on the role of rho family GTPases and their regulators in the plasticity of CNS synapses, as related to brain disease and recovery from brain injury. We are currently focussing on a regulator of the GTPase Rac1 which is upregulated with n...
Dr Michael Coleman
We lose 30-50% of our axons with age and more still in neurodegenerative disease, usually exceeding neuronal loss. In both, the mechanisms are poorly understood but the experimental axon injury model, resulting in Wallerian degeneration, has led t...
Dr Tony Coll
My current research continues to focus upon the roles of the hypothalamus in the control of energy balance. Our current understanding of the central control of appetite has relied heavily upon mouse models and I continue to utilise the power of b...
Professor William Colledge
My research group is interested in the neuroendocrine regulation of mammalian fertility using transgenic mice as a model system. Puberty and the regulation of mammalian fertility is controlled by hormonal signalling within the hypothalamus. My re...
Professor V. Peter Collins
The group is focusing on human brain tumours. The studies aim at documenting the genetic abnormalities involved in the development of these tumours and how these affect cell function. We wish to identify prognostic markers, therapy response marker...
Professor Alastair Compston
My research interests focus on clinical and experimental demyelinating disease with an emphasis on multiple sclerosis - the commonest potentially disabling disease of young adults. The research group has a broad set of interests: we work on the a...
Dr Geoffrey Cook
My research concerns the mechanisms controlling axon growth. In the laboratory we are investigating two axon-repulsive systems, 1) the chatacterization of somite glycoproteins that repel axons, creating the segmented pattern of spinal nerves duri...
Professor Dermot Cooper
Calcium-sensitive adenylyl cyclases are a key interface between Calcium and cyclic AMP signalling in the brain. These enzymes have been critically implicated in various models of learning and memory and fine control of neurotransmitter release. Ou...
Professor Andrew Crawford
I am interested in biophysics and physiology of the vertebrate inner ear , especially the cochlea. My research has focussed on the electrophysiology of cochlear hair cells with a view to understanding how they manage to respond to nanometre dis...
Dr Hannah Critchlow
In 2011 I joined the multi award-winning Naked Scientists team (http://www.thenakedscientists.com), who are based at the University of Cambridge where they produce science and medicine radio programmes and podcasts that are broadcast international...
Dr Damian Crowther
We are dedicated to understanding the molecular pathogenesis of neurodegenerative diseases using the fruit fly, Drosophila melanogaster, as our primary tool. Our creation of a fly model of Alzheimer's disease by expressing the amyloid beta peptid...
Dr Anthony Davenport
Our research group focuses on understanding the role of G-protein-coupled receptors (GPCRs, targets for about ~50% of current drugs) together with their transmitters in humans. We use in vitro pharmacology and in vivo imaging using positron emissi...
Dr Bazbek Davletov
Secretion of neurotransmitters and hormones is under tight control in our bodies and abnormalities in this process can lead to various neurological and endocrine disorders. Neurotransmitters and hormones are released when secretory vesicles fuse w...
Dr Mario de Bono
We seek to understand how neural networks are assembled, function and evolve. C. elegans is a powerful system to study neural circuits. The worm has exactly 302 neurons each of which can be identified. EM reconstructions have identified synapti...
Professor Christopher Dobson
Our group is investigating the molecular origins of neurodegenerative disorders, such as Alzheimer’s and Parkinson’s Disease, that are characterised neuropathologically by the presence of amyloid fibrils. The aim of our research is to understand ...
Dr Steve Edgley
I’m interested in how movements are controlled. Our everyday movements are performed with little conscious thought and are remarkably precise. Despite what the textbooks tell you, the way in which this is accomplished is poorly understood. I work ...
Dr Peter Evans
The research of my group is focussed on signalling mechanisms through 7-transmembrane spanning G-protein coupled receptors (GPCRs). We are currently specifically focussing our research on rapid non-genomic actions of steroids through GPCRs. We ha...
Dr Mark Evans
My group are interested in (1) how brain detects changes in blood glucose and how this glucose-sensing interacts with peripheral metabolism; (2) how defences against hypoglycaemia (low blood sugar) may become abnormal in diabetes; (3) the short an...
Dr Jan Felix Evers
Coordinated behaviour is the end result of successful neuronal network assembly. During development, the excitability and connectivity of each neuron must be controlled to ensure that a functional network is built. I am particularly interested in ...
Professor James Fawcett
Axon regeneration in the damaged CNS: Regeneration of axons after CNS damage is blocked by several molecules, partcularly by proteoglycans in the extracellular matrix. We are developing methods to digest proteglycans, inhibit their production, and...
Dr Emilio Fernandez-Egea
My research interests are mostly the biological and clinical aspects of chronic schizophrenia. I’m the Clozapine Clinic Lead and the Good Outcome Schizophrenia Clinic lead for the local MH Trust (Cambridgeshire and Peterborough NHS Foundation Trus...
Professor Robin Franklin
The Franklin lab is interested in the mechanisms of CNS regeneration with a particular focus on remyelination, an adult stem/precursor cell-mediated process in which new myelin sheaths are restored to demyelinated axons. Using developmental-, tran...
Dr Kristian Franze
I am mainly interested in the mechanics and optics of cells of the nervous system. Using atomic force and confocal microscopy as well as a dual-beam IR-laser trap called 'optical stretcher' passive and active mechanical properties of nervous tissu...
Dr Tim Fryer
My research concentrates on positron emission tomography (PET) methodology, with particular emphasis on the quantitative accuracy of the physiological parameters derived from the data. Current research themes are: parametric mapping using b...
Dr Maria Giannakou
Alzheimer's disease is the most common disease caused by protein aggregation. The major neuropathological characteristics of AD are extracellular plaques of a peptide called amyloid beta and intracellular tangles of hyperphosphorylated tau protein...
Dr Dino Giussani
We have intertwined our interests in oxygen and the development of the central nervous and cardiovascular systems to propose that oxidative stress underlies the common molecular pathway via which prenatal hypoxia contributes to a developmental ori...
Dr Michel Goedert
Alzheimer's disease and Parkinson's disease are characterized by the presence of abnormal filamentous assemblies within some nerve cells. Similar assemblies are found in related disorders, including progressive supranuclear palsy, dementia with Le...
Professor Seth Grant FRSE
The Genes to Cognition programme (G2C) established a framework for studying genes, brain and behaviour in order to link basic molecular research from genomes and experimental genetic organisms with human clinical studies of cognition. The G2C fra...
Dr Ingo Greger
Glutamate is the major excitatory neurotransmitter in vertebrate brains. Glutamate-gated ion channels (iGluRs) mediate the majority of fast synaptic transmission, and are key regulators of synaptic plasticity. The subunit composition of iGluRs, a...
Dr Jules Griffin
We have been using a range of analytical techniques, and in particular NMR spectroscopy and mass spectrometry, to follow metabolism in the brain in a range of disease processes. This ranges from flux measurements to understand the cycling of metab...
Professor John Griffiths
My work involves the use and development of Magnetic Resonance methods for understanding the biology of cancer and the determination of tumour-associated MR parameters for diagnosis, prognosis and monitoring of therapy.
Dr Jochen Guck
The paradigm that neurons in the CNS cannot regenerate is gone. While most research to date is biochemical, there are also physical aspects that need to be considered. We are developing tools to investigate axonal growth and to direct in a certain...
Professor Roger Hardie
Phototransduction, TRP channels and Calcium signalling in Drosophila Phototransduction in the fruitfly Drosophila is an important model for G-protein coupled signalling and fascinating in its own right. We study the underlying cellular and molecu...
Professor William Harris
Where does the nervous system come from in the embryo? How does it grow to the right size and shape? How do stem cells turn into more committed neuronal progenitors and how do these cells know when to leave the cycle and differentiate into neural ...
Dr Michael Hastings FRS, FMedSci
Cellular and molecular basis to circadian rhythms in mammals and its relevance to metabolic and neurological disease.
Professor Christine Holt FRS FMedSci
My laboratory studies how nerve connections are first established in the brain. Our studies focus on the developing visual system and our main goal is to understand the molecular and cellular mechanisms of axon guidance that enable axons to naviga...
Professor Robin Irvine
All my research centres around inositides, which fall into two groups, inositol lipids and inositol phosphates. Most of our work focuses on some of the kinases that phosphorylate inositides, and the functions of their substrates and products, incl...
Dr Tony Jackson
1) Sodium channels contain both alpha and beta subunits. The beta subunits regulate channel kinetics and assembly. The beta subunit extracellular region is homologous to the immunoglobulin domain found in cell adhesion molecules, and beta subunits...
Dr Thomas Jahn
The hallmark of numerous neurodegenerative disorders is the accumulation of microscopic protein deposits such as the amyloid plaques in Alzheimer's Disease and the Lewy Bodies of Parkinson's Disease. My research is focused on understanding the rel...
Dr Gregory Jefferis
Our broad goal is to understand how smell turns into behaviour in the fruit fly brain. We use a combination of genetic labelling and manipulation, targeted in vivo whole cell patch clamp recording and high resolution neuroanatomy to study olfactor...
Dr Susan Jones
The primary focus of our research is the function of AMPA and NMDA glutamate receptors at excitatory synapses in the brain. We study the properties of glutamate receptors, glutamatergic synaptic transmission, and synaptic plasticity. We are intere...
Professor Clemens Kaminski
We develop advanced microscopic imaging techniques that permit us to elucidate molecular mechanisms of neurodegeneration. We use techniques such as lifetime, spectrum and polarisation resolved imaging that inform on protein misfolding, aggregat...
Dr Ragnhildur Thora Karadottir
My lab’s interests are neurotransmitter signalling to oligodendrocytes and their progenitor cells, in both health and disease. Oligodendrocytes produce myelin (in the CNS), which speeds the propagation of the action potential. When the myelin s...
Professor Roger Keynes
Growth cone repulsion is an important mechanism controlling axon growth. During development it guides axons by excluding them from repulsive regions of the embryo. Following injury to the adult brain it may also block axon regeneration, with major...
Dr Maksym Kopanitsa
There are good reasons to believe that phenomena underlying synaptic plasticity are very important in the formation of memories. It is especially evident in the hippocampus, the part of the brain which is critical for spatial memory. For example, ...- Dr Mark Kotter
My group is interested in the biology of adult CNS stem and precursor cells in the context of disease. A particular focus lies on mechanisms of CNS remyelination, a stem/precursor cell-mediated process in which new myelin sheaths are restored to d... 
Dr Leon Lagnado
We are investigating the cellular and molecular mechanisms regulating synaptic transmission and the way these determine the processing of information by a neural circuit. The circuit we are concentrating on is the retina and the question that guid...
Dr Andras Lakatos
Andras is interested in the adaptive changes in glia-neuron interactions following remote axonal insults, such as axotomy and demyelination. The particular focus is how endogenous cortical/gray matter astrocytes and stem cells responding to such c...
Dr Matthias Landgraf
Development of neural networks - from the morphogenesis of dendritic trees to patterns of connections. As neuronal circuits form, synaptic terminals are delivered to specific regions of the nervous system so that connections can form between appr...
Professor Simon Laughlin
Our group is interested in discovering design principles that govern the structure and function of neurons and neural circuits. We record from well-defined neurons, mainly in flies’ visual systems, to measure the molecular and cellular factors tha...
Dr Nicolas Le Novere
My scientific interests revolve around signal transduction in neurons, ranging from the molecular structure of membrane proteins involved in neurotransmission to modelling signalling pathways. A strong focus is the molecular and cellular basis of ...
Dr Joff Lee
I am interested in the mechanisms of memory formation and persistence at the neural systems and molecular neurobiological level. In particular, a primary focus of research relates to the phenomenon of memory reconsolidation, the process that resta...
Dr Rick Livesey
A fundamental question in neural stem cell biology is how distinct classes of neurons are generated at specific places and times in the nervous system in order for them to be incorporated correctly into neuronal circuits. We study this question in...
Dr Darren Logan
Our research interest is in understanding the molecular and genetic basis of olfaction, and how that influences behaviour. Our wider aim is to characterise the neural circuits that instruct stereotyped hard-wired behaviours, and investigate how th...
Dr Leila Luheshi
My research is focused on understanding the origins of protein aggregation in neurodegenerative diseases and the relationship between protein aggregation and the pathogenesis of these diseases. I aim to achieve this through cross-disciplinary, co...
Dr Sarah Lummis
My lab works on Cys-loop receptors, which are one of the major classes of ligand-gated ion channels. The family includes in its vertebrate members 5-HT3, nACh, GABAA, GABAC, and glycine receptors. Proteins from this family are critical for fast sy...
Professor Keith Martin
The main goal of our group is to understand better the mechanisms of retinal ganglion cell (RGC) death in glaucoma, the leading cause of irreversible blindness worldwide. We aim to develop methods to protect RGC thus slowing the progression of gla...
Dr Tarik Massoud
My current interests are in experimental molecular neuroimaging of reporter gene expression, as applied to imaging protein-protein interactions and signal transduction in brain gliomas and neural stem cells, within living subjects.
Dr Hugh Matthews
Phototransduction and olfactory transduction. Calcium homeostasis in vertebrate photoreceptors and olfactory receptors, and its role in modulating their electrical responses to stimulation. Light-induced calcium release within the photoreceptor ou...
Dr Harvey McMahon
Molecular mechanisms of vesicle exocytosis, endocytosis and membrane trafficking in neurons. We are interested in understanding basic mechanisms of vesicle trafficking, especially at the synapse, where synaptic vesicle exocytosis and endocytosi...
Professor Peter McNaughton
We are working on the mechanisms by which sensory receptors transduce stimuli into a nervous impulse which can be detected by the central nervous system as a sensation. Our current areas of activity are in nociceptors (pain-sensitive neurons) and ...
Dr Su Metcalfe
The application of nanotechnology to healthcare - nano-medicine - is now recognised worldwide as a new era in clinical medicine. Currently untreatable illnesses including neurodegenerative diseases (NDD) present key future targets for nano-therape...
Dr Amy Milton
Memory is a critical function of the brain, but little is known about the mechanisms by which memories are modified, adapted, and persist. Memories are known to 'reconsolidate' undergoing updating and strengthening following their destabilisation ...- Dr Eric Miska
We are interested in all aspects of gene regulation by regulatory RNA. Current research themes include: miRNA biology and pathology, miRNA mechanism, piRNA biology and the germline, endo-siRNAs in epigenetic inheritance and evironmental conditioni... 
Dr Emad Moeendarbary
I am a mechanical engineer by training with a strong interest in the experimental and theoretical/computational study of biological systems. Presently, I am working at the interface of engineering and neuroscience to study mechanics of neurons ...- Professor Jenny Morton
Our research is focused on understanding the mechanisms underlying neurodegeneration and on developing strategies to delay or prevent the death of neurones in injured or degenerating brain, particularly in Huntington's disease. We are also interes... - Dr Nicholas Mundy
We study the evolutionary genetics of sensory systems in primates. In particular, we are interested in the evolution and selection of colour vision polymorphisms in New World monkeys and lemurs, and the evolution of olfactory and vomeronasal recep... 
Dr Ruth Murrell-Lagnado
We are interested in the structure, function and cell biology of ion channels and in particular the P2X family of membrane receptors. These cation channels open on binding extracellular ATP, and are widely distributed throughout all major systems ...
Dr Cahir O'Kane
We use Drosophila as a model organism to study synapse function. Questions of major interest include the mechanisms of synaptic vesicle trafficking, and the roles of cellular trafficking pathways in the pathology of neurodegenerative diseases. Rec...
Dr Birgitta Olofsson
How does an animal evaluate food and how is this information used to modify its feeding behaviour appropriately? In many animals food provides a reinforcing feedback after it is eaten that influences subsequent food-seeking behaviour. Variation ...
Dr Swidbert Ott
Our broad goal is to understand the mechanisms that enable animals of a given genotype to adjust to changes in their environment. As an experimental model we use Phase Change in the Desert Locust, an extreme and economically devastating example of...
Dr David Parker
My lab examines how interactions in neuronal networks generate behaviourally relevant network outputs, using the lamprey spinal cord locomotor network as a model system. We combine electrophysiological, computational, molecular, and anatomical app...
Professor Ole Paulsen
The primary interest of my group is the relationship between network oscillations and synaptic plasticity. Network oscillations naturally organise spike timing conducive to spike timing-dependent plasticity (STDP), a strong candidate for a mechani...
Professor Roger Pedersen
Our principal objective is to define the molecular and genetic basis for the maintenance of the pluripotent status of human embryonic stem cells, and similarly, the basis for their differentiation into the primary body lineages: mesoderm, endoderm...
Dr Anna Philpott
Mechanisms that link the cell cycle and differentiation are poorly understood and still less is known about how developmental cues are linked to cell cycle exit. Our laboratory is interested in understanding the coordination of cell proliferation ...
Dr Stefano Pluchino
Recent evidence from our own laboratory indicates that the systemic injection of somatic neural stem/precursor cells (NPCs) very efficiently protect the CNS from the chronic degeneration induced by inflammation both in small rodents as well as in ...
Dr Taufiq Rahman
My research interests broadly lie in two categories - structure-function studies of intracellular calcium channels and rational design and development of selective modulators of signalling proteins including ion channels
Dr Lucy Raymond
The group aims to understand the molecular mechanisms underlying intellectual disability in humans. Our main focus is on families with X linked disease. In collaboration with The Wellcome Trust Sanger Institute, we are using a new approach to dise...
Dr Akhilesh Reddy
My group is interested in circadian rhythms, which are daily cycles of physiology and behaviour that persist when organisms are isolated from the outside world. They represent a fundamental biological mechanism, and are present at all levels of li...
Dr Evan Reid
My group's research is focussed on the hereditary spastic paraplegias, genetic conditions where the corticospinal tract axons degenerate. HSPs selectively involve axons while sparing the neuronal cell bodies, so we study them to understand molecul...- Dr Patrick Riss
My research is focussed on radiochemistry with short lived positron emitting radionuclides. This includes the development of efficient methods for radiolabelling of small molecules as well as the synthesis and validation of radiotracers for Positr... 
Dr Rhys Roberts
Our group is interested in peripheral nerve diseases, particularly the inherited peripheral neuropathies, Charcot-Marie-Tooth disease (CMT). We have focused on the demyelinating forms of CMT, where defects in intracellular membrane trafficking p...
Dr Hugh Robinson
We study synaptic integration in mammalian cortical neurons - encoding of synaptic inputs into patterns of action potentials, or spikes. We are currently interested in - development of advanced electrical stimulation techniques (conductan...
Professor David Rubinsztein
The pathogenesis of diseases caused by codon reiteration mutations (like Huntington’s disease and oculopharangeal muscular dystrophy). Description of research: We are studying the pathogenesis of diseases caused by codon reiteration mutations, l...- Dr Stephen Sawcer
In our research we are attempting to identify genetic factors that influence susceptibility to multiple sclerosis or determine other aspects of the disease. Epidemiological evidence indicates that the genetic architecture underlying susceptibility... 
Dr William Schafer
The fundamental nature of mental phenomena such as perception, learning and memory is one of the remaining scientific mysteries. Since the neuroanatomy of mammalian nervous systems is exceedingly complex and incompletely characterized, it is diffi...
Dr Christof Schwiening
Electrical activity of neurones is associated with calcium influx through various channels. Most neurones extrude this calcium very rapidly on the plasma-membrane calcium pump (PMCA). Our research shows that this extrusion occurs in exchange for h...
Professor Ben Simons
I am interesting in applying methods of non-equilibrium statistical mechanics and population dynamics to lineage tracing studies to investigate mechanisms of stem cell fate in development and maintenance. As well as neurogenesis in adult mammalian...
Dr Ewan Smith
The main interest of the Smith lab is to understand the molecular mechanisms by which sensory neurones detect noxious stimuli, so-called nociceptors. We are particularly interested in how acid activates nociceptors in both physiological and pathop...
Professor Maria Grazia Spillantini
Our interest is in the identification of the mechanisms leading to neuronal death and clinical phenotype in diseases such as Alzheimer's disease, Parkinson's disease and frontotemporal dementia. In particular we study the role of microtubule-assoc...- Professor Peter St George-Hyslop
My laboratory focuses upon understanding the causes and molecular mechanisms of neurodegenerative diseases such as Alzheimer's Disease, Parkinson's Disease and Fronto-Temporal Dementia. We and others have shown that these diseases are frequently c... 
Professor Karen Steel
Hearing impairment is very common in human populations, but it is a very heterogeneous disorder with a wide range of causes including environmental insults as well as genetic components. It is difficult to disentangle the causes of hearing impairm...
Dr David Tannahill
I have worked on a range of model systems from Xenopus and zebrafish to chicks and mice. My current research is focused on building an atlas that describes where and when large numbers of genes are expressed in the developing mouse embryo. For thi...
Professor Colin Taylor
Roles of inositol trisphosphate (IP3) receptors in generating intracellular calcium signals. Structural determinants of IP3 receptor behaviour. Decoding of calcium signals.
Professor Roger Thomas
Intracellular ion homeostasis in nerve cells. I use pH and Ca2+ sensitive microelectrodes to study ionic interactions inside large snail neurones. I am currently investigating the Ca:H coupling ratio of the plasma membrane Ca pump, or PMCA.
Dr Gergely Toth, MBA
My research interests include the targeting of intrinsically disordered proteins by small molecules, which misfold and lose their native functions and/or gain toxic functions implicated in neurodegenerative diseases. We are working on multidisci...
Dr Jernej Ule
Alternative pre-mRNA splicing increases the ability of our body to produce various cell types with diverse proteomes. We take a three-pronged strategy to study splicing regulation on a genome-wide scale. We use computational approaches, assays to ...
Dr Nigel Unwin
I am interested in finding out how ion channels work, using electron microscopy to analyse their structures trapped in different physiological states. Current research focuses on the nicotinic acetylcholine receptor, the transmitter-gated ion chan...
Dr Elizabeth Warburton
Research interests are as follows 1. Molecular imaging of atheroma - particularly carotid plaque imaging using PET and MRI techniques. Both Clinical and microPET imaging. Proof of principle trials of novel atheroma drugs with imaging biomarkers...
Dr Colin Watts
Lab-based research is focused on the genomics of glioblastoma (GBM) and in the role of glial progenitors in their evolution and development. We are also interested in developing patient-specific models of GBM to evaluate intra-tumour variability i...- Dr Ian Winter
Primitive neural mechanisms of auditory scene analysis. My research searches for neurophysiological correlates of the cues necessary for the segregation and fusion of auditory objects. This work is carried out in close collaboration with psychop... - Dr Peter Wooding
Correlation between placental structure and function using light and electron microscopy for structure and immunocytochemistry and in situ hybridisation for function. The focus is mainly on ruminants but includes comparative studies on a wide vari... 
Professor Geoff Woods
As a Clinical Geneticist my interest is in defining and understand Mendelain diseases. I ascertain and assess families and thier phenotypes, perform molecular genetic studies to find the putative pathogeneic mutations causing the family phenotype,...
Dr Kojiro Yano
Systems biology of Neuronal stem cells. This laboratory is carrying out systems biology-oriented studies of mouse neural cells together with the Cambridge Computational Biology Institute (CCBI). Dynamic properties of intracellular signalling tran...
Dr Giles Yeo
I study brain control of body-weight, and currently have two main aims: 1.) To determine a role for FTO in energy balance. SNPs in FTO are strongly associated with obesity. FTO is nutritionally regulated within the ARC, and modulating FTO expres...
Dr Chao Zhao
My research focuses on the mechanism of remyelination of the central nervous system after demyelination in various conditions. After demyelinating injury, the system activates a repair process, which involves oligodendrocyte progenitor cells turni...
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