Publication information

Bibliographic entry:

Herbert J, Goodyer IM, Grossman AB, Hastings MH, de Kloet ER, Lightman SL, Lupien SJ, Roozendaal B, Seckl JR (2006) “Do corticosteroids damage the brain?” J Neuroendocrinol 18(6):393-411


Corticosteroids are an essential component of the body's homeostatic system. In common with other such systems, this implies that corticosteroid levels in blood and, more importantly, in the tissues remain within an optimal range. It also implies that this range may vary according to circumstance. Lack of corticosteroids, such as untreated Addison's disease, can be fatal in humans. In this review, we are principally concerned with excess or disturbed patterns of circulating corticosteroids in the longer or shorter term, and the effects they have on the brain.

Online links:Available online from Blackwell Publishing
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Publication type:Review
Publication status:In print
Publication date:2006 Jun
Record status:PubMed - indexed for MEDLINE