Zara Goozee

Zara Goozee

University position

PhD student
Supervised by Barry Everitt, Emiliano Merlo

Departments

Department of Psychology

Institutes

Behavioural and Clinical Neuroscience Institute

Email

zyg21@cam.ac.uk

Home page

http://www.psychol.cam.ac.uk/

Research Themes

Cognitive and Behavioural Neuroscience

Cellular and Molecular Neuroscience

Interests

My research focuses on the molecular mechanisms of associative memory formation and persistence. In particular I am investigating the consequences of reactivation of a fully consolidated associative memory which can result in two opposing processes, reconsolidation and extinction. Both processes have distinct molecular signatures but at present, the transition from reconsolidation to extinction processes is little understood at the molecular or systems level.

I am using behavioural, pharmacological and molecular techniques to study the dynamic molecular landscape, particularly in the basolateral amygdala and medial prefrontal cortex, in order to better understand the mechanisms governing the maintenance or reduction of a maladaptive memory in the context of drug addiction.

Research Focus

Keywords

Reconsolidation

Extinction

Calcineurin

Behaviour

Appetitive Memory

Clinical conditions

Addiction

Anxiety disorders

Post-traumatic stress disorder

Equipment

Behavioural analysis

Western Blot

Collaborators

Cambridge

Barry Everitt

Emiliano Merlo

Associated News Items


    Publications

    2014

    Merlo E, Milton AL, GoozĂ©e ZY, Theobald DE, Everitt BJ (2014), “Reconsolidation and extinction are dissociable and mutually exclusive processes: behavioral and molecular evidence.” J Neurosci 34(7):2422-31 Details