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Department
  • Surgery
  • Research Theme Beyond the Neuron
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    Dr Umar Sadat

    University Position
    Clinical Lecturer

    Interests

    1. Ultrasound, Computerised Tomography, Magnetic resonance imaging, Cellular Imaging of atherosclerosis 2. Role of biomechanics in pathogenesis of atherosclerotic plaques, aortic aneurysms and in aortic stent graft design & failure 3. Contrast-induced acute kidney injury

    Key Publications

    Publications

    Study on the association of wall shear stress and vessel structural stress with atherosclerosis: An experimental animal study.

    DOI: http://doi.org/10.1016/j.atherosclerosis.2021.01.017
    Journal: Atherosclerosis
    E-pub date: 1 Mar 2021
    Authors: Z Teng, S Wang, A Tokgoz, V Taviani, J Bird, U Sadat, Y Huang, AJ Patterson, N Figg, MJ Graves, JH Gillard

    Vascular Positron Emission Tomography and Restenosis in Symptomatic Peripheral Arterial Disease: A Prospective Clinical Study.

    DOI: http://doi.org/10.1016/j.jcmg.2019.03.031
    Journal: JACC Cardiovasc Imaging
    E-pub date: 1 Apr 2020
    Authors: MM Chowdhury, JM Tarkin, MS Albaghdadi, NR Evans, EPV Le, TB Berrett, U Sadat, FR Joshi, EA Warburton, JR Buscombe, PD Hayes, MR Dweck, DE Newby, JHF Rudd, PA Coughlin

    Influence of overlapping pattern of multiple overlapping uncovered stents on the local mechanical environment: A patient-specific parameter study.

    DOI: http://doi.org/10.1016/j.jbiomech.2017.06.048
    Journal: J Biomech
    E-pub date: 26 Jul 2017
    Authors: S Wang, Y Zhang, J Feng, Y Huang, A Tokgoz, U Sadat, JH Gillard, Q Lu, Z Teng

    Magnetic Resonance Imaging-Based Assessment of Carotid Atheroma: a Comparative Study of Patients with and without Coronary Artery Disease.

    DOI: http://doi.org/10.1016/j.jstrokecerebrovasdis.2016.09.028
    Journal: J Stroke Cerebrovasc Dis
    E-pub date: 1 Feb 2017
    Authors: A Usman, U Sadat, Z Teng, MJ Graves, JR Boyle, K Varty, PD Hayes, JH Gillard

    Scan-Rescan Reproducibility of High Resolution Magnetic Resonance Imaging of Atherosclerotic Plaque in the Middle Cerebral Artery.

    DOI: http://doi.org/10.1371/journal.pone.0134913
    Journal: PLoS One
    E-pub date: 1 Aug 2015
    Authors: X Zhang, C Zhu, W Peng, B Tian, L Chen, Z Teng, J Lu, U Sadat, D Saloner, Q Liu

    Management of complicated aortic aneurysms using multiple overlapping uncovered stents: mid-term outcome from a cohort study.

    DOI: http://doi.org/10.1097/MD.0000000000000209
    Journal: Medicine (Baltimore)
    E-pub date: 1 Dec 2014
    Authors: Y Zhang, Z Teng, Q Lu, Z Zhao, J Bao, X Feng, R Feng, Z Chen, Y Huang, U Sadat, JH Gillard, Z Jing

    Plaque hemorrhage in carotid artery disease: Pathogenesis, clinical and biomechanical considerations

    DOI: http://doi.org/10.1016/j.jbiomech.2014.01.013
    Journal: J Biomech
    E-pub date: 3 Mar 2014
    Authors: Z Teng, U Sadat, AJ Brown, JH Gillard

    How does juxtaluminal calcium affect critical mechanical conditions in carotid atherosclerotic plaque? An exploratory study.

    DOI: http://doi.org/10.1109/TBME.2013.2275078
    Journal: IEEE Trans Biomed Eng
    E-pub date: 1 Jan 2014
    Authors: Zhongzhao Teng, Jing He, U Sadat, JR Mercer, Xiaoyan Wang, NS Bahaei, OM Thomas, JH Gillard

    3D high-resolution contrast enhanced MRI of carotid atheroma – a technical update

    DOI: http://doi.org/10.1016/j.mri.2014.01.019
    Journal: Magnetic Resonance Imaging
    E-pub date: 1 Jan 2014
    Authors: C Zhu, U Sadat, AJ Patterson, Z Teng, JH Gillard, MJ Graves

    Intraplaque stretch in carotid atherosclerotic plaque–an effective biomechanical predictor for subsequent cerebrovascular ischemic events.

    DOI: http://doi.org/10.1371/journal.pone.0061522
    Journal: PLoS One
    E-pub date: 1 Aug 2013
    Authors: Z Teng, U Sadat, W Wang, NS Bahaei, S Chen, VE Young, MJ Graves, JH Gillard

    In vivo MRI-based simulation of fatigue process: a possible trigger for human carotid atherosclerotic plaque rupture.

    DOI: http://doi.org/10.1186/1475-925X-12-36
    Journal: Biomed Eng Online
    E-pub date: 23 Apr 2013
    Authors: Y Huang, Z Teng, U Sadat, J He, MJ Graves, JH Gillard

    Critical mechanical conditions around neovessels in carotid atherosclerotic plaque may promote intraplaque hemorrhage

    DOI: http://doi.org/10.1016/j.atherosclerosis.2012.06.015
    Journal: Atherosclerosis
    E-pub date: 31 Aug 2012
    Authors: Z Teng, J He, AJ Degnan, S Chen, U Sadat, NS Bahaei, JHF Rudd, JH Gillard

    Stress-strain profile of carotid plaque with and without juxtaluminal hemorrhage/thrombus: A possible mechanism for subsequent cerebrovascular events

    DOI: http://doi.org/10.1115/SBC2011-53078
    Journal: ASME 2011 Summer Bioengineering Conference, SBC 2011
    E-pub date: 1 Dec 2011
    Authors: Z Teng, U Sadat, JH Gillard

    Characterization of healing following atherosclerotic carotid plaque rupture in acutely symptomatic patients: an exploratory study using in vivo cardiovascular magnetic resonance.

    DOI: http://doi.org/10.1186/1532-429X-13-64
    Journal: J Cardiovasc Magn Reson
    E-pub date: 27 Oct 2011
    Authors: Z Teng, AJ Degnan, U Sadat, F Wang, VE Young, MJ Graves, S Chen, JH Gillard

    Non-uniform shrinkage for obtaining computational start shape for in-vivo MRI-based plaque vulnerability assessment.

    DOI: http://doi.org/10.1016/j.jbiomech.2011.06.014
    Journal: J Biomech
    E-pub date: 11 Aug 2011
    Authors: Y Huang, Z Teng, U Sadat, S Hilborne, VE Young, MJ Graves, JH Gillard

    Ultrasmall superparamagnetic iron oxide-enhanced magnetic resonance imaging of abdominal aortic aneurysms–a feasibility study.

    DOI: http://doi.org/10.1016/j.ejvs.2010.08.022
    Journal: Eur J Vasc Endovasc Surg
    E-pub date: 1 Feb 2011
    Authors: U Sadat, V Taviani, AJ Patterson, VE Young, MJ Graves, Z Teng, TY Tang, JH Gillard

    Multi-scale segmentation of carotid artery wall in MRI images

    DOI: http://doi.org/10.1109/ICISE.2010.5688938
    Journal: 2nd International Conference on Information Science and Engineering, ICISE2010 - Proceedings
    E-pub date: 1 Dec 2010
    Authors: W Fang, G Qiu, SY Chen, T Zhongzhao, U Sadat, J Gillard

    Biomechanical structural stresses of atherosclerotic plaques.

    DOI: http://doi.org/10.1586/erc.10.130
    Journal: Expert Rev Cardiovasc Ther
    E-pub date: 1 Oct 2010
    Authors: U Sadat, Z Teng, JH Gillard

    Association between biomechanical structural stresses of atherosclerotic carotid plaques and subsequent ischaemic cerebrovascular events–a longitudinal in vivo magnetic resonance imaging-based finite element study.

    DOI: http://doi.org/10.1016/j.ejvs.2010.07.015
    Journal: European Journal of Vascular and Endovascular Surgery
    E-pub date: 1 Jan 2010
    Authors: U Sadat, Z Teng, VE Young, SR Walsh, ZY Li, MJ Graves, K Varty, JH Gillard