Dr Sharon Morein-Zamir

Sharon Morein-Zamir

University position

Research Associate

Departments

Department of Psychology

Institutes

Behavioural and Clinical Neuroscience Institute

Home page

http://www.anglia.ac.uk/science... (personal home page)

Research Theme

Cognitive and Behavioural Neuroscience

Interests

I study different psychological and neuropsychological aspects of compulsivity and impulsivity. For example, I investigate how people control their actions and inhibit or change them when the behaviours are deemed no longer appropriate or disruptive.

I am also interested in how individuals cope with varying levels of uncertainty. Whilst most people find high uncertainty stressful and unpleasant, many react similarly even to much milder levels of uncertainty.

My research bridges different approaches to disorders characterized by compulsivity, such as Obsessive Compulsive Disorder. Better understanding the cognitive, subjective maladaptive thoughts and neural underpinnings of compulsivity will enable more effective interventions and ultimately prevention.

Research Focus

Keywords

cognition

executive function

inhibition

control

multisensory

Clinical conditions

Addiction

Anxiety disorders

Attention deficit hyperactivity disorder

Eating disorders

Obsessive compulsive disorder

Equipment

Behavioural analysis

Magnetic resonance imaging (MRI)

Neuropsychological testing

Collaborators

Cambridge

Karen Ersche

Trevor Robbins

International

Avishai Henik Web: http://medic.bgu.ac.il/brain/h...

Alan Kingstone Web: http://bar.psych.ubc.ca/People/...

Associated News Items


    Key publications

    Morein-Zamir S, Papmeyer M, Gillan CM, Crockett MJ, Fineberg NA, Sahakian BJ, Robbins TW (2012), “Punishment promotes response control deficits in obsessive-compulsive disorder: evidence from a motivational go/no-go task.” Psychol Med :1-10 Details

    Morein-Zamir S, Fineberg NA, Robbins TW, Sahakian BJ (2010), “Inhibition of thoughts and actions in obsessive-compulsive disorder: extending the endophenotype?” Psychol Med 40(2):263-72 Details

    Morein-Zamir S, Hommersen P, Johnston C, Kingstone A (2008), “Novel Measures of Response Performance and Inhibition in Children with ADHD.” J Abnorm Child Psychol Details

    Morein-Zamir S, Chua R, Franks I, Nagelkerke P, & Kingstone A (2007), “Expectancies influence response inhibition and response control” Journal of Experimental Psychology: Human Perception & Performance 33(1):149-162 Details

    Morein-Zamir S, Soto-Faraco S, Kingstone A (2003), “The capture of vision by audition: Deconstructing temporal ventriloquism” Cognitive Brain Research 17:154-163

    Publications

    2014

    Eagle DM, Noschang C, d'Angelo LS, Noble C, Day JO, Dongelmans ML, Theobald DE, Mar AC, Urcelay GP, Morein-Zamir S, Robbins TW (2014), “The dopamine D2/D3 receptor agonist quinpirole increases checking-like behaviour in an operant observing response task with uncertain reinforcement: A novel possible model of OCD.” Behav Brain Res Details

    Fineberg NA, Chamberlain SR, Goudriaan AE, Stein DJ, Vanderschuren LJ, Gillan CM, Shekar S, Gorwood PA, Voon V, Morein-Zamir S, Denys D, Sahakian BJ, Moeller FG, Robbins TW, Potenza MN (2014), “New developments in human neurocognition: clinical, genetic, and brain imaging correlates of impulsivity and compulsivity.” CNS Spectr 19(1):69-89 Details

    Gillan CM, Morein-Zamir S, Durieux AM, Fineberg NA, Sahakian BJ, Robbins TW (2014), “Obsessive-compulsive disorder patients have a reduced sense of control on the illusion of control task.” Front Psychol 5:204 Details

    Morein-Zamir S, Dodds C, van Hartevelt TJ, Schwarzkopf W, Sahakian B, Müller U, Robbins T (2014), “Hypoactivation in right inferior frontal cortex is specifically associated with motor response inhibition in adult ADHD.” Hum Brain Mapp Details

    Voon V, Irvine MA, Derbyshire K, Worbe Y, Lange I, Abbott S, Morein-Zamir S, Dudley R, Caprioli D, Harrison NA, Wood J, Dalley JW, Bullmore ET, Grant JE, Robbins TW (2014), “Measuring "waiting" impulsivity in substance addictions and binge eating disorder in a novel analogue of rodent serial reaction time task.” Biol Psychiatry 75(2):148-55 Details

    2013

    Gillan CM, Morein-Zamir S, Kaser M, Fineberg NA, Sule A, Sahakian BJ, Cardinal RN, Robbins TW (2013), “Counterfactual Processing of Economic Action-Outcome Alternatives in Obsessive-Compulsive Disorder: Further Evidence of Impaired Goal-Directed Behavior.” Biol Psychiatry Details

    Gillan CM, Morein-Zamir S, Urcelay GP, Sule A, Voon V, Apergis-Schoute AM, Fineberg NA, Sahakian BJ, Robbins TW (2013), “Enhanced Avoidance Habits in Obsessive-Compulsive Disorder.” Biol Psychiatry Details

    Morein-Zamir S, Papmeyer M, Durieux A, Fineberg NA, Sahakian BJ, Robbins TW (2013), “Investigation of attentional bias in obsessive compulsive disorder with and without depression in visual search.” PLoS One 8(11):e80118 Details

    Morein-Zamir S, Papmeyer M, Pertusa A, Chamberlain SR, Fineberg NA, Sahakian BJ, Mataix-Cols D, Robbins TW (2013), “The profile of executive function in OCD hoarders and hoarding disorder.” Psychiatry Res Details

    Morein-Zamir S, Simon Jones P, Bullmore ET, Robbins TW, Ersche KD (2013), “Prefrontal hypoactivity associated with impaired inhibition in stimulant-dependent individuals but evidence for hyperactivation in their unaffected siblings.” Neuropsychopharmacology 38(10):1945-53 Details

    2012

    Crockett MJ, Clark L, Apergis-Schoute AM, Morein-Zamir S, Robbins TW (2012), “Serotonin modulates the effects of pavlovian aversive predictions on response vigor.” Neuropsychopharmacology 37(10):2244-52 Details

    2011

    de Rover M, Pironti VA, McCabe JA, Acosta-Cabronero J, Arana FS, Morein-Zamir S, Hodges JR, Robbins TW, Fletcher PC, Nestor PJ, Sahakian BJ (2011), “Hippocampal dysfunction in patients with mild cognitive impairment: a functional neuroimaging study of a visuospatial paired associates learning task.” Neuropsychologia 49(7):2060-70 Details

    Dodds CM, Morein-Zamir S, Robbins TW (2011), “Dissociating inhibition, attention, and response control in the frontoparietal network using functional magnetic resonance imaging.” Cereb Cortex 21(5):1155-65 Details

    Ersche KD, Barnes A, Jones PS, Morein-Zamir S, Robbins TW, Bullmore ET (2011), “Abnormal structure of frontostriatal brain systems is associated with aspects of impulsivity and compulsivity in cocaine dependence.” Brain 134(Pt 7):2013-24 Details

    Gillan CM, Papmeyer M, Morein-Zamir S, Sahakian BJ, Fineberg NA, Robbins TW, de Wit S (2011), “Disruption in the Balance Between Goal-Directed Behavior and Habit Learning in Obsessive-Compulsive Disorder.” Am J Psychiatry Details

    Sahakian BJ, Morein-Zamir S (2011), “Neuroethical issues in cognitive enhancement.” J Psychopharmacol 25(2):197-204 Details

    2010

    Morein-Zamir S, Craig KJ, Ersche KD, Abbott S, Muller U, Fineberg NA, Bullmore ET, Sahakian BJ, Robbins TW (2010), “Impaired visuospatial associative memory and attention in obsessive compulsive disorder but no evidence for differential dopaminergic modulation.” Psychopharmacology (Berl) 212(3):357-67 Details

    Morein-Zamir S, Sahakian BJ (2010), “Neuroethics and public engagement training needed for neuroscientists.” Trends Cogn Sci 14(2):49-51 Details

    2009

    Sahakian BJ, Morein-Zamir S (2009), “Neuroscientists need neuroethics teaching.” Science 325(5937):147 Details

    2007

    Morein-Zamir S, Turner DC, Sahakian BJ (2007), “A review of the effects of modafinil on cognition in schizophrenia.” Schizophr Bull 33(6):1298-306 Details

    Sahakian B, Morein-Zamir S (2007), “Professor's little helper.” Nature 450(7173):1157-9 Details

    2006

    Morein-Zamir S, Chua R, Franks I, Nagelkerke P, Kingstone A (2006), “Measuring online volitional response control with a continuous tracking task.” Behav Res Methods 38(4):638-47 Details

    Morein-Zamir S, Kingstone A (2006), “Fixation offset and stop signal intensity effects on saccadic countermanding: a crossmodal investigation.” Exp Brain Res 175(3):453-62 Details

    Morein-Zamir S, Nagelkerke P, Chua R, Franks I, Kingstone A (2006), “Compatibility effects in stopping and response initiation in a continuous tracking task.” Q J Exp Psychol (Colchester) 59(12):2148-61 Details

    2005

    Morein-Zamir S, Henik A, Balas M, Soroker N (2005), “Differential processing of word and color in unilateral spatial neglect.” Brain Res Cogn Brain Res 23(2-3):259-69 Details

    Soto-Faraco S, Morein-Zamir S, Kingstone A (2005), “On audiovisual spatial synergy: the fragility of the phenomenon.” Percept Psychophys 67(3):444-57 Details

    2004

    Morein-Zamir S, Nagelkerke P, Chua R, Franks I, Kingstone A (2004), “Inhibiting prepared and ongoing responses: is there more than one kind of stopping?” Psychon Bull Rev 11(6):1034-40 Details

    Scheres A, Oosterlaan J, Geurts H, Morein-Zamir S, Meiran N, Schut H, Vlasveld L, Sergeant JA (2004), “Executive functioning in boys with ADHD: primarily an inhibition deficit?” Arch Clin Neuropsychol 19(4):569-94 Details

    2003

    Morein-Zamir S, Meiran N (2003), “Individual stopping times and cognitive control: converging evidence for the stop signal task from a continuous tracking paradigm.” Q J Exp Psychol A 56(3):469-89 Details

    Morein-Zamir S, Soto-Faraco S, Kingstone A (2003), “Auditory capture of vision: examining temporal ventriloquism.” Brain Res Cogn Brain Res 17(1):154-63 Details

    Scheres A, Oosterlaan J, Swanson J, Morein-Zamir S, Meiran N, Schut H, Vlasveld L, Sergeant JA (2003), “The effect of methylphenidate on three forms of response inhibition in boys with AD/HD.” J Abnorm Child Psychol 31(1):105-20 Details

    2002

    Kingstone A, Klein R, Morein-Zamir S, Hunt A, Fisk J, Maxner C (2002), “Orienting attention in aging and Parkinson's disease: distinguishing modes of control.” J Clin Exp Neuropsychol 24(7):951-67 Details

    Morein-Zamir S, Henik A, Spitzer-Davidson I (2002), “The importance of irrelevant-dimension variability in the stroop flanker task.” Psychon Bull Rev 9(1):119-25 Details