Dr Sian Alexander DPhil MRCP
Neurology Specialist Registrar
I am a full time Neurology Specialist Registrar in the East of England. In addition to training in general neurology, I have a particular interest in the mechanisms of cognitive disturbance - memory, language and behaviour.
I investigated the aetiology of acquired memory deficits in autoimmune limbic encephalitis during my D Phil. I subsequently researched cellular mechanisms of neurodegeneration and clinical aspects of cognitive disorders, as part of the academic clinical training pathway. I am now continuing my clinical training in Neurology.
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Associated News Items
Alexander SK, Brown JM, Graham A, Nestor PJ (2014), “CADASIL presenting with a behavioural variant frontotemporal dementia phenotype.” J Clin Neurosci 21(1):165-7 Details
Alexander SK, Holland AJ (in press), “Down Syndrome as a Model for Investigating Alzheimer’s Disease” ACNR
Alexander SK, Rittman T, Xuereb JH, Bak TH, Hodges JR, Rowe JB (2014), “Validation of the new consensus criteria for the diagnosis of corticobasal degeneration.” J Neurol Neurosurg Psychiatry 85(8):925-9 Details
Chang T, Alexopoulos H, McMenamin M, Carvajal-González A, Alexander SK, Deacon R, Erdelyi F, Gabor S, Lang B, Blaes F, Brown P, Vincent A (2013), “Neuronal surface and glutamic acid decarboxylase autoantibodies in Nonparaneoplastic stiff person syndrome.” JAMA Neurol 70(9):1140-9 Details
Alam M, Alexander SK, Asbey M, Higgins JN, Kirkpatrick PJ (2012), “Mirror-image temporal arteriovenous malformations presenting with left cervical internal carotid aneurysm.” Br J Neurosurg 26(6):921-2 Details
Alexander SK, Acosta-Cabronero J, Pengas G, Diaz-de-Grenu L, Nestor PJ (2012), “Beyond the hippocampus: memory impairment in AD might also relate to restrosplenial damage” J Neurol Neurosurg Psychiatry 83:Suppl 2 15doi:10.1136/jnnp-2012-304200a.58
Irani SR, Alexander S, Vincent A (2012), “Case 34-2011: a man with memory loss and partial seizures.” N Engl J Med 366(8):768-9; author reply 769 Details
Irani SR, Alexander S, Waters P, Kleopa KA, Pettingill P, Zuliani L, Peles E, Buckley C, Lang B, Vincent A (2010), “Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan's syndrome and acquired neuromyotonia.” Brain 133(9):2734-48 Details
Watson R, Jepson JE, Bermudez I, Alexander S, Hart Y, McKnight K, Roubertie A, Fecto F, Valmier J, Sattelle DB, Beeson D, Vincent A, Lang B (2005), “Alpha7-acetylcholine receptor antibodies in two patients with Rasmussen encephalitis.” Neurology 65(11):1802-4 Details