Dr Robert Smith

Robert Smith

University position

Radiochemistry Laboratory Manager

Departments

Department of Clinical Neurosciences

Institutes

Wolfson Brain Imaging Centre

Home page

http://www.wbic.cam.ac.uk

Research Theme

Developmental Neuroscience

Interests

My role is to facilitate the production of Radiopharmaceuticals for the PET scanner under the auspices of our MHRA Specials & IMP Licences - ensuring materials supplied are manufactured under GMP conditions.

Research Focus

Keywords

None specified

Clinical conditions

No direct clinical relevance

Equipment

FPLC/HPLC

Positron Emission Tomography (PET)

Collaborators

No collaborators listed

Associated News Items


    Key publications

    Takasawa M, Beech JS, Fryer TD, Hong YT, Hughes JL, Igase K, Jones PS, Smith R, Aigbirhio FI, Menon DK, Clark JC, Baron JC (2007), “Imaging of brain hypoxia in permanent and temporary middle cerebral artery occlusion in the rat using 18F-fluoromisonidazole and positron emission tomography: a pilot study” J Cereb Blood Flow Metab 27(4):679-89 Details

    Publications

    2013

    del Campo N, Fryer TD, Hong YT, Smith R, Brichard L, Acosta-Cabronero J, Chamberlain SR, Tait R, Izquierdo D, Regenthal R, Dowson J, Suckling J, Baron JC, Aigbirhio FI, Robbins TW, Sahakian BJ, Müller U (2013), “A positron emission tomography study of nigro-striatal dopaminergic mechanisms underlying attention: implications for ADHD and its treatment.” Brain 136(Pt 11):3252-70 Details

    2012

    Riss PJ, Ferrari V, Brichard L, Burke P, Smith R, Aigbirhio FI (2012), “Direct, nucleophilic radiosynthesis of [18F]trifluoroalkyl tosylates: improved labelling procedures.” Org Biomol Chem 10(34):6980-6 Details

    2011

    del Campo N, Tait RJ, Acosta-Cabronero J, Hong YT, Izquierdo-Garcia D, Smith R, Aigbirhio FI, Sahakian BJ, Müller U, Robbins TW, Fryer TD (2011), “Quantification of receptor-ligand binding potential in sub-striatal domains using probabilistic and template regions of interest.” Neuroimage 55(1):101-12 Details

    Hong YT, Beech JS, Smith R, Baron JC, Fryer TD (2011), “Parametric mapping of [18F]fluoromisonidazole positron emission tomography using basis functions.” J Cereb Blood Flow Metab 31(2):648-57 Details

    Takasawa M, Beech JS, Fryer TD, Jones PS, Ahmed T, Smith R, Aigbirhio FI, Baron JC (2011), “Single-subject statistical mapping of acute brain hypoxia in the rat following middle cerebral artery occlusion: A microPET study.” Exp Neurol 229(2):251-8 Details