Dr Rolf Ypma

University position

Research Associate


Department of Psychiatry


Brain Mapping Unit

Home page


Research Theme

Systems and Computational Neuroscience


I work on graph theoretical analysis and statistical reconstruction of brain networks, using rsfMRI data on humans and viral tracer studies in mice. I am further interested in relating these abstract global networks to local neurobiological properties.

Research Focus


complex networks

viral tracers

Clinical conditions



Computational modelling



Ed Bullmore

Mikail Rubinov

Associated News Items



Jombart T, Aanensen DM, Baguelin M, Birrell P, Cauchemez S, Camacho A, Colijn C, Collins C, Cori A, Didelot X, Fraser C, Frost S, Hens N, Hugues J, Höhle M, Opatowski L, Rambaut A, Ratmann O, Soubeyrand S, Suchard MA, Wallinga J, Ypma R, Ferguson N (2014), “OutbreakTools: a new platform for disease outbreak analysis using the R software.” Epidemics 7:28-34 Details


Enserink R, Ypma R, Donker GA, Smit HA, van Pelt W (2013), “Infectious disease burden related to child day care in the Netherlands.” Pediatr Infect Dis J 32(8):e334-40 Details

Scholle SO, Ypma RJ, Lloyd AL, Koelle K (2013), “Viral substitution rate variation can arise from the interplay between within-host and epidemiological dynamics.” Am Nat 182(4):494-513 Details

Ypma RJ, Altes HK, van Soolingen D, Wallinga J, van Ballegooijen WM (2013), “A sign of superspreading in tuberculosis: highly skewed distribution of genotypic cluster sizes.” Epidemiology 24(3):395-400 Details

Ypma RJ, Donker T, van Ballegooijen WM, Wallinga J (2013), “Finding evidence for local transmission of contagious disease in molecular epidemiological datasets.” PLoS One 8(7):e69875 Details

Ypma RJ, Jonges M, Bataille A, Stegeman A, Koch G, van Boven M, Koopmans M, van Ballegooijen WM, Wallinga J (2013), “Genetic data provide evidence for wind-mediated transmission of highly pathogenic avian influenza.” J Infect Dis 207(5):730-5 Details

Ypma RJ, van Ballegooijen WM, Wallinga J (2013), “Relating phylogenetic trees to transmission trees of infectious disease outbreaks.” Genetics 195(3):1055-62 Details


Ypma RJ, Bataille AM, Stegeman A, Koch G, Wallinga J, van Ballegooijen WM (2012), “Unravelling transmission trees of infectious diseases by combining genetic and epidemiological data.” Proc Biol Sci 279(1728):444-50 Details