Richard Bethlehem

Richard Bethlehem

University position

PhD student
Supervised by Prof. Simon Baron-Cohen


Department of Psychiatry


Autism Research Centre and Brain Mapping Unit

Home page

Research Themes

Cognitive and Behavioural Neuroscience

Systems and Computational Neuroscience


I currently am a Research Associate at the Autism Research Centre and collaborate with the Geschwind lab at UCLA to work on integrated Neuroimaging and Transcriptomics in order to gain better understanding of genetic underpinnings of atypical neurodevelopment. My work is graciously funded by the Autism Research Trust, Marmaduke Sheild Fund and a Parke Davis Exchange fellowship.

I conducted my PhD in Cambridge between 2013 and 2017, funded by the MRC, Pinsent Darwin Trust, and CHESS (Cambridge Home and EU Scholarship Scheme) studying the effects of oxytocin and testosterone administration on resting state and task neural activation in the typical and autistic brain.

Research Focus







Clinical conditions



Behavioural analysis

Electroencephalography (EEG)

Electrophysiological recording techniques


Magnetic resonance imaging (MRI)

Neuropsychological testing

Randomised control trials



Simon Baron-Cohen

Edward Bullmore

Meng-Chuan Lai

Pietro Lio

Michael Lombardo


Daniel Geschwind Web:

Jack van Honk Web:

Associated News Items

Key publications

Romero-Garcia, R., Warrier, V., Bullmore, E.T., Baron-Cohen, S. & Bethlehem, R.A.I. (2018), “Synaptic and transcriptionally downregulated genes are associated with cortical thickness differences in children with autism.” Molecular Psychiatry

Bethlehem R. A. I., Romero-Garcia R., Mak E., Bullmore E.T., Baron-Cohen S. (2017), “Structural Covariance Networks in Children with Autism or ADHD ” Cerebral Cortex Volume 27, Issue 8, 1, Pages 4267–4276,



Heany, S.J., Bethlehem, R.A.I., Van Honk, J., Bos, P.A., Stein, D.J., Terburg, D. (2018), “Testosterone Decouples the Orbitofrontal Cortex from Subcortical Inescapable Threat Reactivity. ” Psychoneuroendocrinology

Lombardo, M.V., Auyeung, B., Pramparo, T., Quartier, A., Courraud, J., Holt, R.J., Waldman, J., Ruigrok, A.N.V., Mooney, N., Bethlehem, R.A.I., Lai, M-C., Kundu, P., Bullmore, E.T., Mandel, J-L., Piton, A. & Baron-Cohen, S. (2018), “Sex-specific impact of prenatal androgens on social brain default mode subsystems.” Molecular Psychiatry

Mak, E., Bethlehem, R.A.I., Rittman, T., Romero-Garcia, R., Cervenka, S., Gabel, S., Surendranathan, A., Bevan-Jones, W.R., Passamonti, L., Vázquez Rodríguez, P., Arnold, R., Hong, Y.T., Fryer T.D., Aigbirhio, F., Rowe, J.B & O’Brien, J.T. (2018), “In vivo mapping of tau deposition on atrophy in alzheimers disease” Alzheimer’s and Dementia: Diagnosis Biomarkers and Assessments


Bethlehem R.A.I., Lombardo M.V., Lai M-C., Auyeung B., Crockford S.K., Deakin J., Soubramanian S., Sule A., Kundu P., Voon V., and Baron-Cohen S. (2017), “Intranasal oxytocin enhances intrinsic corticostriatal functional connectivity in women” Translational Psychiatry e1099


Auyeung B, Lombardo MV, Heinrichs M, Chakrabarti B, Sule A, Deakin JB, Bethlehem RA, Dickens L, Mooney N, Sipple JA, Thiemann P, Baron-Cohen S (2015), “Oxytocin increases eye contact during a real-time, naturalistic social interaction in males with and without autism.” Transl Psychiatry 5:e507 Details


Bethlehem RA, Baron-Cohen S, van Honk J, Auyeung B, Bos PA (2014), “The oxytocin paradox.” Front Behav Neurosci 8:48 Details

Bethlehem RA, Dumoulin SO, Dalmaijer ES, Smit M, Berendschot TT, Nijboer TC, Van der Stigchel S (2014), “Decreased fixation stability of the preferred retinal location in juvenile macular degeneration.” PLoS One 9(6):e100171 Details

Van der Stigchel S, Bethlehem RA (2014), “The contribution of foveal activation to the oculomotor gap effect.” Neurosci Lett 583C:126-129 Details


Bethlehem RA, van Honk J, Auyeung B, Baron-Cohen S (2013), “Oxytocin, brain physiology, and functional connectivity: a review of intranasal oxytocin fMRI studies.” Psychoneuroendocrinology 38(7):962-74 Details

Van der Stigchel S, Bethlehem RA, Klein BP, Berendschot TT, Nijboer TC, Dumoulin SO (2013), “Macular degeneration affects eye movement behavior during visual search.” Front Psychol 4:579 Details


Van der Stigchel S, de Vries JP, Bethlehem R, Theeuwes J (2011), “A global effect of capture saccades.” Exp Brain Res 210(1):57-65 Details