Dr Petra Vertes

Interests

I am an MRC fellow in Bioinformatics at the Brain Mapping Unit (BMU). My work builds on methods and concepts from physics and bioinformatics and applies them to fundamental problems in neuroscience. In particular, I am interested in the structure-function relationship in brain networks, from the microscopic scale of neurons to the large-scale connectivity of brain regions, in both health and disease. Insights into these questions are not only fascinating in their own right, but have important implications for our understanding and therapeutic approaches to cognitive impairments associated with psychiatric disorders, brain injury and ageing.

I received a masters degree in theoretical physics and a PhD in artificial neural networks from the University of Cambridge, UK. I am also one of the co-founders and organizers of the Cambridge Networks Network (CNN), a forum for academics across different disciplines who share an interest in Network Science.

Research Focus

Keywords

Network Topology

Brain development

Neuroimaging

C elegans

Transcriptomics

Clinical conditions

Schizophrenia

Equipment

Computational modelling

Collaborators

Cambridge

Aaron Alexander-Bloch

Ed Bullmore

Sylvia Richardson

William Schafer

United Kingdom

Tom Duke

Vito Latora

Tom Nichols

International

Laszlo Barabasi

Dani Bassett

Amit Etkin

Associated News Items


Key publications

Whitaker KJ*, Vértes PE*, Romero-Garcia R, Váša F, Moutoussis M, Prabhu G, Weiskopf N, Callaghan MF, Wagstyl K, Rittman T, Tait R, Ooi C, Suckling J, Inkster B, Fonagy P, Dolan RJ, Jones PB, Goodyer IM, Bullmore ET, NSPN Consortium (2016), “Adolescence is associated with genomically patterned consolidation of the hubs of the human brain connectome.” PNAS 113 (32), 9105-9110

Vértes PE, Rittman T, Whitaker KJ, Romero-Garcia R, Váša F, Kitzbichler MG, Wagstyl K, Fonagy P, Dolan RJ, Jones PB, Goodyer IM, Bullmore ET, NSPN Consortium (2016), “Gene transcription profiles associated with inter-modular hubs and connection distance in human functional magnetic resonance imaging networks.” Philosophical Transactions of the Royal Society B: Biological Sciences 371, 20150362.

Vértes PE, Alexander-Bloch AF, Gogtay N, Giedd JN, Rapoport JL, Bullmore ET (2012), “Simple models of human brain functional networks.” Proc Natl Acad Sci U S A 109(15):5868-73 Details

Publications

2016

Bentley B, Branicky R, Barnes CL, Chew YL, Yemini E, Bullmore ET, Vértes PE*, Schafer WR* (2016), “The multilayer connectome of Caenorhabditis elegans” Plos Com Bio 12 (12) e1005283

Betzel RF, Avena-Koenigsberger A, Goñi J, He Y, de Reus MA, Griffa A, Vértes PE, Mišic B, Thiran J-P, Hagmann P, van den Heuvel M, Zuo X-N, Bullmore ET and Sporns O (2016), “Generative models of the human connectome” Neuroimage 124, 1054-1064.

Fernandez-Egea E*, Vértes PE*, Flint SM*, Turner L, Mustafa S, Hatton A, Smith KGC, Lyons PA, Bullmore ET (2016), “Peripheral Immune Cell Populations Associated with Cognitive Deficits and Negative Symptoms of Treatment-Resistant Schizophrenia.” 
PloS One 11 (5), e0155631.

Jao T, Li C-W, Vértes PE, Wu CW, Achard S, Hsieh C-H, Liou C-H, Chen J-H, Bullmore ET (2016), “Large-scale functional brain network reorganization during Taoist meditation.
” Brain connectivity 6(1), 9-24

Rittman T, Rubinov M, Vértes PE, Patel AX, Ginestet CE, Ghosh BCP, Barker RA, Spillantini MG, Bullmore ET, Rowe JB (2016), “Regional expression of the MAPT gene is associated with loss of hubs in brain networks and cognitive impairment in Parkinson disease and progressive supranuclear palsy.” Neurobiol Aging 48:153-160.

Vaghi MM, Vértes PE, Kitzbichler MG, Apergis-Schoute AM, van der Flier FE, Fineberg NA, Sule A, Zaman R, Voon V, Kundu P, Bullmore ET, Robbins TW (2016), “Specific fronto-striatal circuits for impaired cognitive flexibility and goal-directed planning in Obsessive-Compulsive Disorder: Evidence from resting-state functional connectivity.
” Biological Psychiatry

2015

Vértes PE, Bullmore ET (2015), “Annual research review: Growth connectomics--the organization and reorganization of brain networks during normal and abnormal development.” J Child Psychol Psychiatry 56(3):299-320 Details

2014

Alstott J, Panzarasa P, Rubinov M, Bullmore ET, Vértes PE (2014), “A unifying framework for measuring weighted rich clubs.” Sci Rep 4:7258 Details

Patel AX, Kundu P, Rubinov M, Jones PS, Vértes PE, Ersche KD, Suckling J, Bullmore ET (2014), “A wavelet method for modeling and despiking motion artifacts from resting-state fMRI time series.” Neuroimage 95:287-304 Details

Pavlovic DM, Vértes PE, Bullmore ET, Schafer WR, Nichols TE (2014), “Stochastic Blockmodeling of the Modules and Core of the Caenorhabditis elegans Connectome.” PLoS One 9(7):e97584 Details

Vértes PE, Alexander-Bloch A, Bullmore ET (2014), “Generative models of rich clubs in Hebbian neuronal networks and large-scale human brain networks.” Philos Trans R Soc Lond B Biol Sci 369(1653) Details

2013

Bullmore E, Vértes P (2013), “From Lichtheim to rich club: brain networks and psychiatry.” JAMA Psychiatry 70(8):780-2 Details

Crossley NA, Mechelli A, Vértes PE, Winton-Brown TT, Patel AX, Ginestet CE, McGuire P, Bullmore ET (2013), “Cognitive relevance of the community structure of the human brain functional coactivation network.” Proc Natl Acad Sci U S A 110(28):11583-8 Details

Jao T, Vértes PE, Alexander-Bloch AF, Tang IN, Yu YC, Chen JH, Bullmore ET (2013), “Volitional eyes opening perturbs brain dynamics and functional connectivity regardless of light input.” Neuroimage 69:21-34 Details

Kundu P, Brenowitz ND, Voon V, Worbe Y, Vértes PE, Inati SJ, Saad ZS, Bandettini PA, Bullmore ET (2013), “Integrated strategy for improving functional connectivity mapping using multiecho fMRI.” Proc Natl Acad Sci U S A 110(40):16187-92 Details

Nicosia V, Vértes PE, Schafer WR, Latora V, Bullmore ET (2013), “Phase transition in the economically modeled growth of a cellular nervous system.” Proc Natl Acad Sci U S A 110(19):7880-5 Details

Towlson EK, Vértes PE, Ahnert SE, Schafer WR, Bullmore ET (2013), “The rich club of the C. elegans neuronal connectome.” J Neurosci 33(15):6380-7 Details

2012

Achard S, Delon-Martin C, Vértes PE, Renard F, Schenck M, Schneider F, Heinrich C, Kremer S, Bullmore ET (2012), “Hubs of brain functional networks are radically reorganized in comatose patients.” Proc Natl Acad Sci U S A 109(50):20608-13 Details

Alexander-Bloch AF, Vértes PE, Stidd R, Lalonde F, Clasen L, Rapoport J, Giedd J, Bullmore ET, Gogtay N (2012), “The Anatomical Distance of Functional Connections Predicts Brain Network Topology in Health and Schizophrenia.” Cereb Cortex Details

Barkóczi B, Juhász G, Averkin RG, Vörös I, Vertes P, Penke B, Szegedi V (2012), “GluA1 phosphorylation alters evoked firing pattern in vivo.” Neural Plast 2012:286215 Details

Nicol RM, Chapman SC, Vértes PE, Nathan PJ, Smith ML, Shtyrov Y, Bullmore ET (2012), “Fast reconfiguration of high-frequency brain networks in response to surprising changes in auditory input.” J Neurophysiol 107(5):1421-30 Details

2011

Vértes PE, Nicol RM, Chapman SC, Watkins NW, Robertson DA, Bullmore ET (2011), “Topological isomorphisms of human brain and financial market networks.” Front Syst Neurosci 5:75 Details

2010

Vertes PE, Duke T (2010), “Effect of network topology on neuronal encoding based on spatiotemporal patterns of spikes.” HFSP J 4(3-4):153-63 Details