Mr Przemyslaw Jarzebowski

Interests

I look at the development of cortical cultures and use a comparative approach to quantitatively characterise differences in neural activity between healthy and diseased cultures. In my research project I study activity in a culture with a mutation in its NMDA receptor, which is a genetic model of Rett syndrome. We record its spontaneous activity using multi-electrode arrays. The research aims to establish how the neural network malfunctions in the disease, so different pharmaceutical agents can be applied in search for experimental treatments.

Research Focus

Keywords

None specified

Clinical conditions

Autism

Equipment

Calcium imaging

Cell culture

Computational modelling

Collaborators

Cambridge

Stephen Eglen

Susanna Mierau

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