Dr Nicholas Perentos
In neurodegenerative diseases such as Huntington's disease neuronal networks undergo dramatic changes. Understanding these changes at early stages of the disease may provide opportunities for therapeutic targets. I use behavior with concurrent electroencephalography, local field potentials, and multiple single neuron recordings to characterise such changes in a model of Huntington's disease.
Electrophysiological recording techniques
Associated News Items
McBride SD, Perentos N, Morton AJ. (2016), “A mobile, high-throughput semi-automated system for testing cognition in large non-primate animal models of Huntington disease.” J Neurosci Methods. 30(265): 25-33
Nicol AU, Perentos N, Martins AQ, Morton AJ. (2016), “Automated detection and characterisation of rumination in sheep using in vivo electrophysiology.” Physiol Behav. 17(163):258-266
Perentos N, Martins AQ, Cumming R, Mitchell NL, Palmer DN, Sawiak SJ and Morton AJ (in press), “An EEG investigation of sleep homeostasis in healthy and CLN5 Batten disease affected sheep” J. Neurosci.
McBride SD, Perentos N, Morton AJ (2015), “Understanding the concept of a reflective surface: can sheep improve navigational ability through the use of a mirror?” Anim Cogn 18(1):361-71 Details
Perentos N, Martins AQ, Watson TC, Bartsch U, Mitchell NL, Palmer DN, Jones MW, Morton AJ (2015), “Translational neurophysiology in sheep: measuring sleep and neurological dysfunction in CLN5 Batten disease affected sheep.” Brain 138(Pt 4):862-74 Details
Perentos N, Croft RJ, McKenzie RJ, Cosic I (2013), “The alpha band of the resting electroencephalogram under pulsed and continuous radio frequency exposures.” IEEE Trans Biomed Eng 60(6):1702-10 Details
N. Perentos, S. Iskra, A. Faraone, R, McKenzie, G. Bit-Babik and V. Anderson, (2012), “Exposure Compliance Methodologies for Multiple Input Multiple Output (MIMO) Enabled Networks and Terminals”, IEEE Transactions on Antennas and Propagation” IEEE Transactions on Antennas and Propagation 60(2):644-53
Perentos N, Croft RJ, McKenzie RJ, Cvetkovic D, Cosic I (2008), “The effect of GSM-like ELF radiation on the alpha band of the human resting EEG.” Conf Proc IEEE Eng Med Biol Soc 2008:5680-3 Details
Perentos N, Iskra S, McKenzie RJ, Cosi I (2008), “Simulation of pulsed ELF magnetic fields generated by GSM mobile phone handsets for human electromagnetic bioeffects research.” Australas Phys Eng Sci Med 31(3):235-42 Details
Perentos N, Croft RJ, McKenzie RJ, Cvetkovic D, Cosic I (2007), “Comparison of the effects of continuous and pulsed mobile phone like RF exposure on the human EEG.” Australas Phys Eng Sci Med 30(4):274-80 Details