Dr Peter Connick

Peter Connick

University position

PhD student
Supervised by Dr Siddharthan Chandran

Departments

Department of Clinical Neurosciences

Institutes

Cambridge Centre for Brain Repair

Email

pc349@cam.ac.uk

Home page

http://www-neurosciences.medschl.cam.ac.uk/

Research Themes

Clinical and Veterinary Neuroscience

Cellular and Molecular Neuroscience

The Cambridge Neuroscience Community

Interests

Funded via the MRC Experimental Medicine programme, I am coordinating a phase I/IIA clinical trial of autologous adult human bone marrow derived mesenchymal stromal cells in multiple sclerosis (MSCIMS).

Developing treatments to prevent or repair axonal loss - the primary correlate of clinical disability - is a key priority for MS research. MSCIMS will begin to test one such candidate therapy. In addition, the development of a clinical science methodologies and research protocols will provide a long-term platform for the wider testing of cellular and generic putative repair therapies in MS and other neurodegenerative diseases.

Research Focus

Keywords

neuroscience

repair

mesenchymal stromal cells

multiple sclerosis

clinical trials

Clinical conditions

Multiple sclerosis

Equipment

Cell culture

Clinical Trial

Immunohistochemistry

Magnetic resonance imaging (MRI)

Microscopy

Collaborators

Cambridge

Jules Griffin

United Kingdom

Thomas Bak Web: http://www.psy.ed.ac.uk/people/...

David Miller Web: http://www.ion.ucl.ac.uk/researc...

International

Jan Brinchmann Web: http://www.stemcell.no/groups/...

Publications

2011

Connick P, Kolappan M, Bak TH, Chandran S (2011), “Verbal fluency as a rapid screening test for cognitive impairment in progressive multiple sclerosis.” J Neurol Neurosurg Psychiatry Details

Connick P, Kolappan M, Patani R, Scott MA, Crawley C, He XL, Richardson K, Barber K, Webber DJ, Wheeler-Kingshott CA, Tozer DJ, Samson RS, Thomas DL, Du MQ, Luan SL, Michell AW, Altmann DR, Thompson AJ, Miller DH, Compston A, Chandran S (2011), “The mesenchymal stem cells in multiple sclerosis (MSCIMS) trial protocol and baseline cohort characteristics: an open-label pre-test: post-test study with blinded outcome assessments.” Trials 12:62 Details

Connick P, Patani R, Chandran S (2011), “Stem cells as a resource for regenerative neurology.” Pract Neurol 11(1):29-36 Details