Dr Nicholas Walsh
I am lecturer in Developmental Psychology at UEA and a Visiting Scientist in the Department of Psychiatry, University of Cambridge.
In my research I am investigating the effects of genetic and early-life environmental factors upon brain structure and function. To do this I am scanning participants from the ROOTS cohort [http://www.roots.group.cam.ac.uk/]. This work is carried out in collaboration with colleagues at the Department of Psychiatry, University of Cambridge and the MRC Cognition and Brain Sciences Unit.
More broadly I am interested in the following areas:
Translational epidemiology / Population Neuroscience
Cognitive control and self-regulation across the life-course.
Effects of the psychosocial environment on brain structure and function over the life-course.
Neural mechanisms of antidepressant treatments: psychological and pharmacological.
For my personal blog see familyneuroscience.com
Cross-sectional and cohort studies
Magnetic resonance imaging (MRI)
Associated News Items
Walsh ND, Dalgleish T, Lombardo MV, Dunn VJ, Van Harmelen AL, Ban M, Goodyer IM (2014), “General and specific effects of early-life psychosocial adversities on adolescent grey matter volume.” Neuroimage Clin 4:308-18 PDF Details
Walsh ND, Dalgleish T, Dunn VJ, Abbott R, St Clair MC, Owens M, Fairchild G, Kerslake WS, Hiscox LV, Passamonti L, Ewbank M, Ban M, Calder AJ, Goodyer IM (2012), “5-HTTLPR-environment interplay and its effects on neural reactivity in adolescents.” Neuroimage 63(3):1670-80 PDF Details
Walsh ND, Williams SC, Brammer MJ, Bullmore ET, Kim J, Suckling J, Mitterschiffthaler MT, Cleare AJ, Pich EM, Mehta MA, Fu CH (2007), “A longitudinal functional magnetic resonance imaging study of verbal working memory in depression after antidepressant therapy” Biological Psychiatry 62 11:1236-1243 Details
Fairchild G, Hagan CC, Passamonti L, Walsh ND, Goodyer IM, Calder AJ (2014), “Atypical neural responses during face processing in female adolescents with conduct disorder.” J Am Acad Child Adolesc Psychiatry 53(6):677-687.e5 Details
Fairchild G, Hagan CC, Walsh ND, Passamonti L, Calder AJ, Goodyer IM (2013), “Brain structure abnormalities in adolescent girls with conduct disorder.” J Child Psychol Psychiatry 54(1):86-95 Details
Owens M, Goodyer IM, Wilkinson P, Bhardwaj A, Abbott R, Croudace T, Dunn V, Jones PB, Walsh ND, Ban M, Sahakian BJ (2012), “5-HTTLPR and early childhood adversities moderate cognitive and emotional processing in adolescence.” PLoS One 7(11):e48482 Details
Walsh N.D. (2011), “Book review of 'Next generation antidepressants: Moving beyond monoamines to discover novel treatment strategies for mood disorders'. Edited by Beyer C.E. and Stahl. S.M.” Psychological Medicine 41, 1109-1111
Cole J, Toga AW, Hojatkashani C, Thompson P, Costafreda SG, Cleare AJ, Williams SC, Bullmore ET, Scott JL, Mitterschiffthaler MT, Walsh ND, Donaldson C, Mirza M, Marquand A, Nosarti C, McGuffin P, Fu CH (2010), “Subregional hippocampal deformations in major depressive disorder.” J Affect Disord Details
Chen CH, Suckling J, Ooi C, Fu CH, Williams SC, Walsh ND, Mitterschiffthaler MT, Pich EM, Bullmore E (2008), “Functional coupling of the amygdala in depressed patients treated with antidepressant medication.” Neuropsychopharmacology 33(8):1909-18 Details
Fu CH, Williams SC, Cleare AJ, Scott J, Mitterschiffthaler MT, Walsh ND, Donaldson C, Suckling J, Andrew C, Steiner H, Murray RM (2008), “Neural responses to sad facial expressions in major depression following cognitive behavioral therapy.” Biol Psychiatry 64(6):505-12 Details
Mitterschiffthaler MT, Williams SC, Walsh ND, Cleare AJ, Donaldson C, Scott J, Fu CH (2008), “Neural basis of the emotional Stroop interference effect in major depression.” Psychol Med 38(2):247-56 Details
Versace A, Almeida JR, Hassel S, Walsh ND, Novelli M, Klein CR, Kupfer DJ, Phillips ML (2008), “Elevated left and reduced right orbitomedial prefrontal fractional anisotropy in adults with bipolar disorder revealed by tract-based spatial statistics.” Arch Gen Psychiatry 65(9):1041-52 Details
Fu CH, Williams SC, Brammer MJ, Suckling J, Kim J, Cleare AJ, Walsh ND, Mitterschiffthaler MT, Andrew CM, Pich EM, Bullmore ET (2007), “Neural responses to happy facial expressions in major depression following antidepressant treatment.” Am J Psychiatry 164(4):599-607 Details
Fu CH, Williams SC, Cleare AJ, Brammer MJ, Walsh ND, Kim J, Andrew CM, Pich EM, Williams PM, Reed LJ, Mitterschiffthaler MT, Suckling J, Bullmore ET (2004), “Attenuation of the neural response to sad faces in major depression by antidepressant treatment: a prospective, event-related functional magnetic resonance imaging study.” Arch Gen Psychiatry 61(9):877-89 Details
Whiskey E, Wykes T, Duncan-McConnell D, Haworth E, Walsh N, Hastilow S (2003), “Continuation of clozapine treatment: Practice makes perfect.” Psychiatric Bulletin 23:211-213