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    Dr Mary McLean

    University Position
    Senior Research Associate

    Interests

    I perform magnetic resonance imaging and spectroscopy studies on patients with brain tumours (as well as tumours of other parts of the body). The aim is to improve non-invasive diagnosis and the prediction and monitoring of response to treatment. Prior to 2007 I spent nine years performing similar studies in a wide gamut of neurological and psychological disorders at the Institute of Neurology, London.

    Key Publications

    Multimodal MRI can identify perfusion and metabolic changes in the invasive margin of glioblastomas.

    DOI: http://doi.org/10.1002/jmri.24996
    Journal: J Magn Reson Imaging
    E-pub date: 1 Feb 2016
    Authors: SJ Price, AMH Young, WJ Scotton, J Ching, LA Mohsen, NR Boonzaier, VC Lupson, JR Griffiths, MA McLean, TJ Larkin

    Publications

    Hyperpolarized 13C MRI: A novel approach for probing cerebral metabolism in health and neurological disease.

    DOI: http://doi.org/10.1177/0271678X20909045
    Journal: J Cereb Blood Flow Metab
    E-pub date: 1 Jun 2020
    Authors: JT Grist, JJ Miller, F Zaccagna, MA McLean, F Riemer, T Matys, DJ Tyler, C Laustsen, AJ Coles, FA Gallagher

    Non-invasive assessment of glioma microstructure using VERDICT MRI: correlation with histology.

    DOI: http://doi.org/10.1007/s00330-019-6011-8
    Journal: Eur Radiol
    E-pub date: 1 Oct 2019
    Authors: F Zaccagna, F Riemer, AN Priest, MA McLean, K Allinson, JT Grist, C Dragos, T Matys, JH Gillard, C Watts, SJ Price, MJ Graves, FA Gallagher

    Quantifying normal human brain metabolism using hyperpolarized [1-13C]pyruvate and magnetic resonance imaging.

    DOI: http://doi.org/10.1016/j.neuroimage.2019.01.027
    Journal: Neuroimage
    E-pub date: 1 Apr 2019
    Authors: JT Grist, MA McLean, F Riemer, RF Schulte, SS Deen, F Zaccagna, R Woitek, CJ Daniels, JD Kaggie, T Matys, I Patterson, R Slough, AB Gill, A Chhabra, R Eichenberger, M-C Laurent, A Comment, JH Gillard, AJ Coles, DJ Tyler, I Wilkinson, B Basu, DJ Lomas, MJ Graves, KM Brindle, FA Gallagher

    Imaging intralesional heterogeneity of sodium concentration in multiple sclerosis: Initial evidence from 23Na-MRI.

    DOI: http://doi.org/10.1016/j.jns.2018.01.027
    Journal: J Neurol Sci
    E-pub date: 15 Apr 2018
    Authors: JT Grist, F Riemer, MA McLean, T Matys, F Zaccagna, SF Hilborne, JP Mason, I Patterson, R Slough, J Kaggie, SS Deen, MJ Graves, JL Jones, AJ Coles, FA Gallagher

    Positron emission tomography-guided magnetic resonance spectroscopy in Alzheimer disease.

    DOI: http://doi.org/10.1002/ana.25202
    Journal: Ann Neurol
    E-pub date: 1 Apr 2018
    Authors: N Sheikh-Bahaei, SA Sajjadi, R Manavaki, M McLean, JT O'Brien, JH Gillard

    [P1–419]: PET‐GUIDED MR SPECTROSCOPY REVEALS DISTINCT RELATIONS BETWEEN BRAIN METABOLITES, AMYLOID AND HYPOMETABOLISM IN ALZHEIMER’S DISEASE

    DOI: http://doi.org/10.1016/j.jalz.2017.06.435
    Journal: Alzheimer's & Dementia
    E-pub date: 1 Jul 2017
    Authors: N Sheikh‐Bahaei, SA Sajjadi, R Manavaki, M McLean, JH Gillard, JT O'Brien

    P3‐249: Magnetic Resonance Spectroscopy Based Metabolite Measurement Differentiates Alzheimer’s From Healthy Brain

    DOI: http://doi.org/10.1016/j.jalz.2016.06.1912
    Journal: Alzheimer's & Dementia
    E-pub date: 1 Jul 2016
    Authors: N Sheikh-Bahaei, SA Sajjadi, R Manavaki, M McLean, JT O'Brien, JH Gillard