Michael Gottschalk M.Sc.

Interests

My projects at the Cambridge Centre of Neuropsychiatric Research (CCNR – under the direction of Prof Sabine Bahn) focus on the molecular basis of affective and anxiety disorders by generating new etiological hypotheses in a systems biological manner. Combining a diverse range of molecular profiling methods (e.g. liquid chromatography coupled tandem mass spectrometry or immuno assays) to a multi-omic approach this aims at a better characterization of the fundamental psychiatric pathophysiology in the CNS (tissue samples) or the periphery (serum/blood). More specifically I am interested in potential biomarkers of mood phases and episode switching in bipolar disorder, add on therapeutics for depressive disorders, markers of treatment efficacy for obsessive compulsive disorder and the pharmacological modulation of emotional states of fear and panic. Future goals include the translation of these findings into novel diagnostic tests and the next generation of neuropsychiatric interventions.

Research Focus

Keywords

biomarker

neuropsychiatric disorders

preclinical modeling

multi-omics

translational medicine

Clinical conditions

Anxiety disorders

Bipolar disorder

Depressive disorders

Obsessive compulsive disorder

Equipment

Behavioural analysis

Computational modelling

Metabolomics

Proteomics

Transcriptomics

Collaborators

No collaborators listed

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