Dr Loes Rutten-Jacobs

Loes Rutten-Jacobs

University position

Research Associate

Departments

Department of Clinical Neurosciences

Institutes

Neurology Unit

Email

lr406@medschl.cam.ac.uk

Home page

http://www.Rutten-Jacobs.com (personal home page)

Research Theme

Clinical and Veterinary Neuroscience

Interests

I am a British Heart Foundation Immediate Research Fellow with a main interest in the investigation of causes, treatment and prognosis of cerebral small vessel disease and stroke, through epidemiological, genetic and imaging approaches.

Research Focus

Keywords

Cerebral Small Vessel Disease

Stroke

Genetics

Epidemiology

Vascular

Clinical conditions

Cerebrovascular disorders

Dementia

Stroke

Equipment

Cross-sectional and cohort studies

Genome-wide association analysis

Magnetic resonance imaging (MRI)

Collaborators

Cambridge

Hugh Markus

Chris Wallace

International

Frank-Erik de Leeuw Web: http://www.ru.nl/people/...

Associated News Items


    Key publications

    Rutten-Jacobs LC, Arntz RM, Maaijwee NA, Schoonderwaldt HC, Dorresteijn LD, van Dijk EJ, de Leeuw FE (2015), “Cardiovascular disease is the main cause of long-term excess mortality after ischemic stroke in young adults.” Hypertension 65(3):670-5 Details

    Rutten-Jacobs LC, Traylor M, Adib-Samii P, Thijs V, Sudlow C, Rothwell PM, Boncoraglio G, Dichgans M, Bevan S, Meschia J, Levi C, Rost NS, Rosand J, Hassan A, Markus HS (2015), “Common NOTCH3 Variants and Cerebral Small-Vessel Disease.” Stroke 46(6):1482-7 Details

    Maaijwee NA, Rutten-Jacobs LC, Schaapsmeerders P, van Dijk EJ, de Leeuw FE (2014), “Ischaemic stroke in young adults: risk factors and long-term consequences.” Nat Rev Neurol 10(6):315-25 Details

    Rutten-Jacobs LC, Arntz RM, Maaijwee NA, Schoonderwaldt HC, Dorresteijn LD, van Dijk EJ, de Leeuw FE (2013), “Long-term mortality after stroke among adults aged 18 to 50 years.” JAMA 309(11):1136-44 Details

    Rutten-Jacobs LC, Maaijwee NA, Arntz RM, Schoonderwaldt HC, Dorresteijn LD, van der Vlugt MJ, van Dijk EJ, de Leeuw FE (2013), “Long-term risk of recurrent vascular events after young stroke: The FUTURE study.” Ann Neurol 74(4):592-601 Details

    Publications

    2015

    Schaapsmeerders P, van Uden IW, Tuladhar AM, Maaijwee NA, van Dijk EJ, Rutten-Jacobs LC, Arntz RM, Schoonderwaldt HC, Dorresteijn LD, de Leeuw FE, Kessels RP (2015), “Ipsilateral hippocampal atrophy is associated with long-term memory dysfunction after ischemic stroke in young adults.” Hum Brain Mapp Details

    2014

    Maaijwee NA, Arntz RM, Rutten-Jacobs LC, Schaapsmeerders P, Schoonderwaldt HC, van Dijk EJ, de Leeuw FE (2014), “Post-stroke fatigue and its association with poor functional outcome after stroke in young adults.” J Neurol Neurosurg Psychiatry Details

    Maaijwee NA, Schaapsmeerders P, Rutten-Jacobs LC, Arntz RM, Schoonderwaldt HC, van Dijk EJ, Kessels RP, de Leeuw FE (2014), “Subjective cognitive failures after stroke in young adults: prevalent but not related to cognitive impairment.” J Neurol 261(7):1300-8 Details

    Rutten-Jacobs LC, Keurlings PA, Arntz RM, Maaijwee NA, Schoonderwaldt HC, Dorresteijn LD, van der Vlugt MJ, van Dijk EJ, de Leeuw FE (2014), “High incidence of diabetes after stroke in young adults and risk of recurrent vascular events: the FUTURE study.” PLoS One 9(1):e87171 Details

    Rutten-Jacobs LC, Maaijwee NA, Arntz RM, Schoonderwaldt HC, Dorresteijn LD, van Dijk EJ, de Leeuw FE (2014), “Clinical characteristics and outcome of intracerebral hemorrhage in young adults.” J Neurol 261(11):2143-9 Details

    Synhaeve NE, Arntz RM, Maaijwee NA, Rutten-Jacobs LC, Schoonderwaldt HC, Dorresteijn LD, de Kort PL, van Dijk EJ, de Leeuw FE (2014), “Poor long-term functional outcome after stroke among adults aged 18 to 50 years: Follow-Up of Transient Ischemic Attack and Stroke Patients and Unelucidated Risk Factor Evaluation (FUTURE) study.” Stroke 45(4):1157-60 Details

    2013

    Arntz R, Rutten-Jacobs L, Maaijwee N, Schoonderwaldt H, Dorresteijn L, van Dijk E, de Leeuw FE (2013), “Post-stroke epilepsy in young adults: a long-term follow-up study.” PLoS One 8(2):e55498 Details

    Arntz RM, Maaijwee NA, Rutten-Jacobs LC, Schoonderwaldt HC, Dorresteijn LD, van Dijk EJ, de Leeuw FE (2013), “Epilepsy after TIA or stroke in young patients impairs long-term functional outcome: the FUTURE Study.” Neurology 81(22):1907-13 Details

    Rutten-Jacobs LC, van Dijk EJ, de Leeuw FE (2013), “Long-term follow-up of young adults with stroke--reply.” JAMA 310(3):321-2 Details

    Schaapsmeerders P, Maaijwee NA, van Dijk EJ, Rutten-Jacobs LC, Arntz RM, Schoonderwaldt HC, Dorresteijn LD, Kessels RP, de Leeuw FE (2013), “Long-term cognitive impairment after first-ever ischemic stroke in young adults.” Stroke 44(6):1621-8 Details

    Yesilot Barlas N, Putaala J, Waje-Andreassen U, Vassilopoulou S, Nardi K, Odier C, Hofgart G, Engelter S, Burow A, Mihalka L, Kloss M, Ferrari J, Lemmens R, Coban O, Haapaniemi E, Maaijwee N, Rutten-Jacobs L, Bersano A, Cereda C, Baron P, Borellini L, Valcarenghi C, Thomassen L, Grau AJ, Palm F, Urbanek C, Tuncay R, Durukan Tolvanen A, van Dijk EJ, de Leeuw FE, Thijs V, Greisenegger S, Vemmos K, Lichy C, Bereczki D, Csiba L, Michel P, Leys D, Spengos K, Naess H, Tatlisumak T, Bahar SZ (2013), “Etiology of first-ever ischaemic stroke in European young adults: the 15 cities young stroke study.” Eur J Neurol 20(11):1431-9 Details

    2012

    Putaala J, Yesilot N, Waje-Andreassen U, Pitkäniemi J, Vassilopoulou S, Nardi K, Odier C, Hofgart G, Engelter S, Burow A, Mihalka L, Kloss M, Ferrari J, Lemmens R, Coban O, Haapaniemi E, Maaijwee N, Rutten-Jacobs L, Bersano A, Cereda C, Baron P, Borellini L, Valcarenghi C, Thomassen L, Grau AJ, Palm F, Urbanek C, Tuncay R, Durukan-Tolvanen A, van Dijk EJ, de Leeuw FE, Thijs V, Greisenegger S, Vemmos K, Lichy C, Bereczki D, Csiba L, Michel P, Leys D, Spengos K, Naess H, Bahar SZ, Tatlisumak T (2012), “Demographic and geographic vascular risk factor differences in European young adults with ischemic stroke: the 15 cities young stroke study.” Stroke 43(10):2624-30 Details

    2011

    Rutten-Jacobs LC, de Leeuw FE, Geurts-van Bon L, Gordinou de Gouberville MC, Schepens-Franke AN, Dederen PJ, Spliet WG, Wesseling P, Kiliaan AJ (2011), “White Matter Lesions Are Not Related to β-Amyloid Deposition in an Autopsy-Based Study.” Curr Gerontol Geriatr Res 2011:826862 Details

    Rutten-Jacobs LC, Maaijwee NA, Arntz RM, Van Alebeek ME, Schaapsmeerders P, Schoonderwaldt HC, Dorresteijn LD, Overeem S, Drost G, Janssen MC, van Heerde WL, Kessels RP, Zwiers MP, Norris DG, van der Vlugt MJ, van Dijk EJ, de Leeuw FE (2011), “Risk factors and prognosis of young stroke. The FUTURE study: a prospective cohort study. Study rationale and protocol.” BMC Neurol 11:109 Details

    2008

    Krabbendam I, Jacobs LC, Lotgering FK, Spaanderman ME (2008), “Venous response to orthostatic stress.” Am J Physiol Heart Circ Physiol 295(4):H1587-93 Details