Miss Laura Brightman

Interests

Looking at an In Vitro model of Prader Willi syndrome, a developmental disorder caused by problems (both deletion and epigenetic) with chromosome 15. Modelling cortical development with human patient IPSC lines.

Dissociated cortical neurons showing glia mediated synapses (red).
Dissociated cortical neurons showing glia mediated synapses (red).
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Research Focus

Keywords

Prader-Willi

development

disease

IPSC

In Vitro

Clinical conditions

Alzheimer's disease

Anxiety disorders

Attention deficit hyperactivity disorder

Autism

Bipolar disorder

Birth defects

Borderline personality disorder

Childhood disorders

Cognitive impairment

Dementia

Depressive disorders

Digestion and nutrition disorders

Eating disorders

Genetic disorders

Hormonal disorders

Learning disabilities

Obsessive compulsive disorder

Personality disorders

Schizophrenia

Stress

Equipment

Calcium imaging

Cell culture

Computational modelling

Confocal microscopy

Electrophysiological recording techniques

Fluorescence microscopy

Immunohistochemistry

Intracellular recording

Magnetic resonance imaging (MRI)

Microscopy

Neuropsychological testing

Whole cell patch clamp

Collaborators

No collaborators listed

Associated News Items


Publications

2013

Samson RS, Ciccarelli O, Kachramanoglou C, Brightman L, Lutti A, Thomas DL, Weiskopf N, Wheeler-Kingshott CA (2013), “Tissue- and column-specific measurements from multi-parameter mapping of the human cervical spinal cord at 3 T.” NMR Biomed 26(12):1823-30 Details