Miss Kate McAllister

Kate McAllister

University position

PhD student
Supervised by Dr Shahid Zaman, Prof Tony Holland

Departments

Department of Psychiatry

Institutes

Cambridge Intellectual and Developmental Disabilities Research Group and Developmental Psychiatry

Home page

http://www.ciddrg.org.uk/people/... (personal home page)

Research Themes

Cognitive and Behavioural Neuroscience

Developmental Neuroscience

The Cambridge Neuroscience Community

Interests

I am based at the Cambridge Intellectual and Developmental Disabilities Research Group as part of the Department of Psychiatry. The focus of my PhD is the role of mitochondrial dysfunction in aging and the development of Alzheimer’s disease in Down's Syndrome (DS), I am supervised by Dr Shahid Zaman and Prof Tony Holland, working closely with the Wellcome Trust Clinical Research Facility at Addenbrooke's, the MRC Mitochondrial Biology Unit, Cambridge, and Newcastle Medical School. This study is part of a larger investigation into amyloid build up in people with DS.

Research Focus

Keywords

Down's syndrome

mitochondria

Alzheimer's disease

aging

developmental

Clinical conditions

Alzheimer's disease

Dementia

Down's Syndrome

Genetic disorders

Learning disabilities

Equipment

Cross-sectional and cohort studies

Magnetic resonance spectroscopy

Neuropsychological testing

Collaborators

Cambridge

Peter Murgatroyd

Mike Murphy

Alison Sleigh

Laura Watson

United Kingdom

Patrick Chinnery

Publications

2013

McAllister CJ, Kelly CL, Manning KE, Holland AJ (2013), “Participant experience of invasive research in adults with intellectual disability.” J Med Ethics Details

Wood NI, McAllister CJ, Cuesta M, Aungier J, Fraenkel E, Morton AJ (2013), “Adaptation to Experimental Jet-Lag in R6/2 Mice despite Circadian Dysrhythmia.” PLoS One 8(2):e55036 Details

2012

Siaperas P, Ring HA, McAllister CJ, Henderson S, Barnett A, Watson P, Holland AJ (2012), “Atypical movement performance and sensory integration in Asperger's syndrome.” J Autism Dev Disord 42(5):718-25 Details

2011

Goodman AO, Rogers L, Pilsworth S, McAllister CJ, Shneerson JM, Morton AJ, Barker RA (2011), “Asymptomatic sleep abnormalities are a common early feature in patients with Huntington's disease.” Curr Neurol Neurosci Rep 11(2):211-7 Details

McAllister CJ, Whittington JE (2011), “A short clinical overview of Prader–Willi syndrome” Clinical Obesity 1 (4-6): 184-186

McAllister CJ, Whittington JE, Holland AJ (2011), “Development of the eating behaviour in Prader-Willi Syndrome: advances in our understanding.” Int J Obes (Lond) 35(2):188-97 Details

2010

Butler JV, Whittington JE, Holland AJ, McAllister CJ, Goldstone AP (2010), “The transition between the phenotypes of Prader-Willi syndrome during infancy and early childhood.” Dev Med Child Neurol 52(6):e88-93 Details

Maywood ES, Fraenkel E, McAllister CJ, Wood N, Reddy AB, Hastings MH, Morton AJ (2010), “Disruption of peripheral circadian timekeeping in a mouse model of Huntington's disease and its restoration by temporally scheduled feeding.” J Neurosci 30(30):10199-204 Details

Wood NI, Carta V, Milde S, Skillings EA, McAllister CJ, Ang YL, Duguid A, Wijesuriya N, Afzal SM, Fernandes JX, Leong TW, Morton AJ (2010), “Responses to environmental enrichment differ with sex and genotype in a transgenic mouse model of Huntington's disease.” PLoS One 5(2):e9077 Details