Professor Jonathan Gillard

Jonathan Gillard

University position

Professor

Professor Jonathan Gillard is pleased to consider applications from prospective PhD students.

Departments

Department of Radiology

Email

jhg21@cam.ac.uk

Research Theme

Clinical and Veterinary Neuroscience

Interests

Development of novel Magnetic Resonance imaging tools assessing atheromatous plaque inflammation and stress analysis.

Development of MRI and PET tools for delineating microscopic brain tumour infiltration in man.

Research Focus

Keywords

Magnetic resonance Imaging

Atherosclerosis

Brain Tumours

mechnaical Stress Analysis

Vascular Imaging

Clinical conditions

Cancers

Cerebrovascular disorders

Huntington's disease

Stroke

Traumatic brain injury

Equipment

Computational modelling

Computerised tomography

Magnetic resonance imaging (MRI)

Positron Emission Tomography (PET)

Collaborators

No collaborators listed

Associated News Items


    Key publications

    Tang TY, Howarth SP, Miller SR, Graves MJ, Patterson AJ, U-King-Im JM, Li ZY, Walsh SR, Brown AP, Kirkpatrick PJ, Warburton EA, Hayes PD, Varty K, Boyle JR, Gaunt ME, Zalewski A, Gillard JH (2009), “The ATHEROMA (Atorvastatin Therapy: Effects on Reduction of Macrophage Activity) Study. Evaluation using ultrasmall superparamagnetic iron oxide-enhanced magnetic resonance imaging in carotid disease.” J Am Coll Cardiol 53(22):2039-50 Details

    Price SJ, Jena R, Burnet NG, Hutchinson PJ, Dean AF, Peña A, Pickard JD, Carpenter TA, Gillard JH (2006), “Improved delineation of glioma margins and regions of infiltration with the use of diffusion tensor imaging: an image-guided biopsy study.” AJNR Am J Neuroradiol 27(9):1969-74 Details

    U-King-Im JM, Hollingworth W, Trivedi RA, Cross JJ, Higgins NJ, Graves MJ, Gutnikov S, Kirkpatrick PJ, Warburton EA, Antoun NM, Rothwell PM, Gillard JH (2005), “Cost-effectiveness of diagnostic strategies prior to carotid endarterectomy.” Ann Neurol 58(4):506-15 Details

    Publications

    2010

    Abdul-Salam VB, Ramrakha P, Krishnan U, Owen DR, Shalhoub J, Davies AH, Tang TY, Gillard JH, Boyle JJ, Wilkins MR, Edwards RJ (2010), “Identification and assessment of plasma lysozyme as a putative biomarker of atherosclerosis.” Arterioscler Thromb Vasc Biol 30(5):1027-33 Details

    Hayes PD, Sadat U, Walsh SR, Noorani A, Tang TY, Bowden DJ, Gillard JH, Boyle JR (2010), “Cost-effectiveness analysis of endovascular versus open surgical repair of acute abdominal aortic aneurysms based on worldwide experience.” J Endovasc Ther 17(2):174-82 Details

    Li ZY, Taviani V, Tang T, Sutcliffe MP, Gillard JH (2010), “The hemodynamic effects of in-tandem carotid artery stenosis: implications for carotid endarterectomy.” J Stroke Cerebrovasc Dis 19(2):138-45 Details

    Moustafa RR, Izquierdo-Garcia D, Fryer TD, Graves MJ, Rudd JH, Gillard JH, Weissberg PL, Baron JC, Warburton EA (2010), “Carotid plaque inflammation is associated with cerebral microembolism in patients with recent transient ischemic attack or stroke: a pilot study.” Circ Cardiovasc Imaging 3(5):536-41 Details

    Moustafa RR, Izquierdo-Garcia D, Jones PS, Graves MJ, Fryer TD, Gillard JH, Warburton EA, Baron JC (2010), “Watershed infarcts in transient ischemic attack/minor stroke with > or = 50% carotid stenosis: hemodynamic or embolic?” Stroke 41(7):1410-6 Details

    Sadat U, Li ZY, Young VE, Graves MJ, Boyle JR, Warburton EA, Varty K, O'Brien E, Gillard JH (2010), “Finite element analysis of vulnerable atherosclerotic plaques: a comparison of mechanical stresses within carotid plaques of acute and recently symptomatic patients with carotid artery disease.” J Neurol Neurosurg Psychiatry 81(3):286-9 Details

    Sadat U, Taviani V, Patterson AJ, Young VE, Graves MJ, Teng Z, Tang TY, Gillard JH (2010), “Ultrasmall Superparamagnetic Iron Oxide-enhanced Magnetic Resonance Imaging of Abdominal Aortic Aneurysms-A Feasibility Study.” Eur J Vasc Endovasc Surg Details

    Sadat U, Teng Z, Gillard JH (2010), “Biomechanical structural stresses of atherosclerotic plaques.” Expert Rev Cardiovasc Ther 8(10):1469-81 Details

    Sadat U, Teng Z, Young VE, Graves MJ, Gillard JH (2010), “Three-dimensional volumetric analysis of atherosclerotic plaques: a magnetic resonance imaging-based study of patients with moderate stenosis carotid artery disease.” Int J Cardiovasc Imaging Details

    Sadat U, Teng Z, Young VE, Walsh SR, Li ZY, Graves MJ, Varty K, Gillard JH (2010), “Association between Biomechanical Structural Stresses of Atherosclerotic Carotid Plaques and Subsequent Ischaemic Cerebrovascular Events - A Longitudinal in Vivo Magnetic Resonance Imaging-based Finite element Study.” Eur J Vasc Endovasc Surg Details

    Sadat U, Teng Z, Young VE, Zhu C, Tang TY, Graves MJ, Gillard JH (2010), “Impact of plaque haemorrhage and its age on structural stresses in atherosclerotic plaques of patients with carotid artery disease: an MR imaging-based finite element simulation study.” Int J Cardiovasc Imaging Details

    Sadat U, Walsh SR, Norden AG, Gillard JH, Boyle JR (2010), “Does Oral N-Acetylcysteine Reduce Contrast-Induced Renal Injury in Patients With Peripheral Arterial Disease Undergoing Peripheral Angiography? A Randomized-Controlled Study.” Angiology Details

    Tang TY, Walsh SR, Sadat U, Gillard JH (2010), “Comment on "Advanced carotid plaque imaging".” Eur J Vasc Endovasc Surg 40(1):139; author reply 139-40 Details

    Taviani V, Hickson SS, Hardy CJ, McEniery CM, Patterson AJ, Gillard JH, Wilkinson IB, Graves MJ (2010), “Age-related changes of regional pulse wave velocity in the descending aorta using Fourier velocity encoded M-mode.” Magn Reson Med Details

    Taviani V, Patterson AJ, Graves MJ, Hardy CJ, Worters P, Sutcliffe MP, Gillard JH (2010), “Accuracy and repeatability of fourier velocity encoded M-mode and two-dimensional cine phase contrast for pulse wave velocity measurement in the descending aorta.” J Magn Reson Imaging 31(5):1185-94 Details

    Taviani V, Patterson AJ, Worters P, Sutcliffe MP, Graves MJ, Gillard JH (2010), “Accuracy of phase contrast, black-blood, and bright-blood pulse sequences for measuring compliance and distensibility coefficients in a human-tissue mimicking phantom.” J Magn Reson Imaging 31(1):160-7 Details

    Teng Z, Sadat U, Li Z, Huang X, Zhu C, Young VE, Graves MJ, Gillard JH (2010), “Arterial luminal curvature and fibrous-cap thickness affect critical stress conditions within atherosclerotic plaque: an in vivo MRI-based 2D finite-element study.” Ann Biomed Eng 38(10):3096-101 Details

    Young VE, Patterson AJ, Sadat U, Bowden DJ, Graves MJ, Tang TY, Priest AN, Skepper JN, Kirkpatrick PJ, Gillard JH (2010), “Diffusion-weighted magnetic resonance imaging for the detection of lipid-rich necrotic core in carotid atheroma in vivo.” Neuroradiology 52(10):929-36 Details

    Zhu C, Teng Z, Sadat U, Young VE, Graves MJ, Li ZY, Gillard JH (2010), “Normalized Wall Index Specific and MRI-Based Stress Analysis of Atherosclerotic Carotid Plaques.” Circ J Details

    2009

    Barrett SR, Sutcliffe MP, Howarth S, Li ZY, Gillard JH (2009), “Experimental measurement of the mechanical properties of carotid atherothrombotic plaque fibrous cap.” J Biomech 42(11):1650-5 Details

    Chappell FM, Wardlaw JM, Young GR, Gillard JH, Roditi GH, Yip B, Pell JP, Rothwell PM, Brown MM, Gough MJ, Randall MS (2009), “Carotid artery stenosis: accuracy of noninvasive tests--individual patient data meta-analysis.” Radiology 251(2):493-502 Details

    Gao H, Long Q, Graves M, Gillard JH, Li ZY (2009), “Study of reproducibility of human arterial plaque reconstruction and its effects on stress analysis based on multispectral in vivo magnetic resonance imaging.” J Magn Reson Imaging 30(1):85-93 Details

    Gao H, Long Q, Graves M, Gillard JH, Li ZY (2009), “Carotid arterial plaque stress analysis using fluid-structure interactive simulation based on in-vivo magnetic resonance images of four patients.” J Biomech 42(10):1416-23 Details

    Gao H, Long Q, Sadat U, Graves M, Gillard JH, Li ZY (2009), “Stress analysis of carotid atheroma in a transient ischaemic attack patient using the MRI-based fluid-structure interaction method.” Br J Radiol 82 Spec No 1:S46-54 Details

    Howarth SP, Tang TY, Trivedi R, Weerakkody R, U-King-Im J, Gaunt ME, Boyle JR, Li ZY, Miller SR, Graves MJ, Gillard JH (2009), “Utility of USPIO-enhanced MR imaging to identify inflammation and the fibrous cap: a comparison of symptomatic and asymptomatic individuals.” Eur J Radiol 70(3):555-60 Details

    Izquierdo-Garcia D, Davies JR, Graves MJ, Rudd JH, Gillard JH, Weissberg PL, Fryer TD, Warburton EA (2009), “Comparison of methods for magnetic resonance-guided [18-F]fluorodeoxyglucose positron emission tomography in human carotid arteries: reproducibility, partial volume correction, and correlation between methods.” Stroke 40(1):86-93 Details

    Li ZY, Sadat U, Gillard JH (2009), “Coronary calcium scoring: calcium location needs to be integrated!” J Am Coll Cardiol 54(8):745; author reply 745-6 Details

    Lobotesis K, U-King-Im JM, Cross JJ, Gillard JH, Antoun NM (2009), “Gliomatosis peritonei associated with a ventriculo-peritoneal shunt.” Clin Radiol 64(1):95-9 Details

    Neumann AB, Jonsdottir KY, Mouridsen K, Hjort N, Gyldensted C, Bizzi A, Fiehler J, Gasparotti R, Gillard JH, Hermier M, Kucinski T, Larsson EM, Sørensen L, Ostergaard L (2009), “Interrater agreement for final infarct MRI lesion delineation.” Stroke 40(12):3768-71 Details

    Patterson AJ, U-King-Im JM, Tang TY, Scoffings DJ, Howarth SP, Graves MJ, Gillard JH (2009), “Association between white matter ischaemia and carotid plaque morphology as defined by high-resolution in vivo MRI.” Eur J Vasc Endovasc Surg 38(2):149-54 Details

    Price SJ, Fryer TD, Cleij MC, Dean AF, Joseph J, Salvador R, Wang DD, Hutchinson PJ, Clark JC, Burnet NG, Pickard JD, Aigbirhio FI, Gillard JH (2009), “Imaging regional variation of cellular proliferation in gliomas using 3'-deoxy-3'-[18F]fluorothymidine positron-emission tomography: an image-guided biopsy study.” Clin Radiol 64(1):52-63 Details

    Sadat U, Boyle JR, Gillard JH, Hayes PD (2009), “Endovascular repair of infrarenal abdominal aortic aneurysms.” Br J Hosp Med (Lond) 70(3):151-3 Details

    Sadat U, Gillard JH, Varty K (2009), “CD36 modulation in the subintimal trapping and LDL-mediated migration of macrophages.” Expert Rev Cardiovasc Ther 7(6):587-90 Details

    Sadat U, Li ZY, Graves MJ, Tang TY, Gillard JH (2009), “Noninvasive imaging of atheromatous carotid plaques.” Nat Clin Pract Cardiovasc Med 6(3):200-9 Details

    Sadat U, Weerakkody RA, Bowden DJ, Young VE, Graves MJ, Li ZY, Tang TY, Gaunt ME, Hayes PD, Gillard JH (2009), “Utility of high resolution MR imaging to assess carotid plaque morphology: A comparison of acute symptomatic, recently symptomatic and asymptomatic patients with carotid artery disease.” Atherosclerosis Details

    Tang TY, Muller KH, Graves MJ, Li ZY, Walsh SR, Young V, Sadat U, Howarth SP, Gillard JH (2009), “Iron oxide particles for atheroma imaging.” Arterioscler Thromb Vasc Biol 29(7):1001-8 Details

    Tang TY, Patterson AJ, Miller SR, Graves MJ, Howarth SP, U-King-Im JM, Li ZY, Sadat U, Young VE, Walsh SR, Boyle JR, Gaunt ME, Gillard JH (2009), “Temporal dependence of in vivo USPIO-enhanced MRI signal changes in human carotid atheromatous plaques.” Neuroradiology 51(7):457-65 Details

    Tang TY, U-King-Im JM, Walsh SR, Young VE, Sadat U, Li ZY, Patterson AJ, Varty K, Gillard JH (2009), “Invasive and non-invasive modalities of imaging carotid stenosis.” J Cardiovasc Surg (Torino) 50(6):715-25 Details

    U-King-Im JM, Young V, Gillard JH (2009), “Carotid-artery imaging in the diagnosis and management of patients at risk of stroke.” Lancet Neurol 8(6):569-80 Details

    2008

    Howarth SP, Li ZY, Tang TY, Graves MJ, U-King-Im JM, Gillard JH (2008), “In vivo positive contrast IRON sequence and quantitative T(2)* measurement confirms inflammatory burden in a patient with asymptomatic carotid atheroma after USPIO-enhanced MR imaging.” J Vasc Interv Radiol 19(3):446-8 Details

    Li ZY, Gillard JH (2008), “Plaque rupture: plaque stress, shear stress, and pressure drop.” J Am Coll Cardiol 52(13):1106-7; author reply 1107 Details

    Li ZY, Gillard JH (2008), “Plaque rupture: plaque stress, shear stress, and pressure drop.” J Am Coll Cardiol 52(6):499-500; author reply 500 Details

    Li ZY, Howarth S, Graves M, Gillard JH (2008), “Measurement of stenotic carotid arterial compliance with MRI.” Conf Proc IEEE Eng Med Biol Soc 2008:1403-6 Details

    Li ZY, Tang T, U-King-Im J, Graves M, Sutcliffe M, Gillard JH (2008), “Assessment of carotid plaque vulnerability using structural and geometrical determinants.” Circ J 72(7):1092-9 Details

    Li ZY, Taviani V, Gillard JH (2008), “The impact of wall shear stress and pressure drop on the stability of the atherosclerotic plaque.” Conf Proc IEEE Eng Med Biol Soc 2008:1373-6 Details

    Li ZY, U-King-Im J, Tang TY, Soh E, See TC, Gillard JH (2008), “Impact of calcification and intraluminal thrombus on the computed wall stresses of abdominal aortic aneurysm.” J Vasc Surg 47(5):928-35 Details

    Müller K, Skepper JN, Tang TY, Graves MJ, Patterson AJ, Corot C, Lancelot E, Thompson PW, Brown AP, Gillard JH (2008), “Atorvastatin and uptake of ultrasmall superparamagnetic iron oxide nanoparticles (Ferumoxtran-10) in human monocyte-macrophages: implications for magnetic resonance imaging.” Biomaterials 29(17):2656-62 Details

    Newcombe VF, Williams GB, Nortje J, Bradley PG, Chatfield DA, Outtrim JG, Harding SG, Coles JP, Maiya B, Gillard JH, Hutchinson PJ, Pickard JD, Carpenter TA, Menon DK (2008), “Concordant biology underlies discordant imaging findings: diffusivity behaves differently in grey and white matter post acute neurotrauma.” Acta Neurochir Suppl 102:247-51 Details

    Sadat U, Cooper DG, Gillard JH, Walsh SR, Hayes PD (2008), “Impact of the type of anesthesia on outcome after elective endovascular aortic aneurysm repair: literature review.” Vascular 16(6):340-5 Details

    Sadat U, Kullar PJ, Noorani A, Gillard JH, Cooper DG, Boyle JR (2008), “Emergency endovascular management of peripheral artery aneurysms and pseudoaneurysms - a review.” World J Emerg Surg 3:22 Details

    Sadat U, Ward C, Gillard JH, Gaunt M (2008), “Caval interruption: methods and indications.” Br J Hosp Med (Lond) 69(9):520-3 Details

    Saleem MA, Sadat U, Walsh SR, Young VE, Gillard JH, Cooper DG, Gaunt ME (2008), “Role of carotid duplex imaging in carotid screening programmes - an overview.” Cardiovasc Ultrasound 6:34 Details

    Takasawa M, Jones PS, Guadagno JV, Christensen S, Fryer TD, Harding S, Gillard JH, Williams GB, Aigbirhio FI, Warburton EA, Østergaard L, Baron JC (2008), “How reliable is perfusion MR in acute stroke? Validation and determination of the penumbra threshold against quantitative PET.” Stroke 39(3):870-7 Details

    Tang TY, Howarth SP, Li ZY, Miller SR, Graves MJ, U-King-Im JM, Trivedi RA, Walsh SR, Brown AP, Kirkpatrick PJ, Gaunt ME, Gillard JH (2008), “Correlation of carotid atheromatous plaque inflammation with biomechanical stress: utility of USPIO enhanced MR imaging and finite element analysis.” Atherosclerosis 196(2):879-87 Details

    Tang TY, Howarth SP, Miller SR, Graves MJ, U-King-Im JM, Li ZY, Walsh SR, Hayes PD, Varty K, Gillard JH (2008), “Comparison of the inflammatory burden of truly asymptomatic carotid atheroma with atherosclerotic plaques in patients with asymptomatic carotid stenosis undergoing coronary artery bypass grafting: an ultrasmall superparamagnetic iron oxide enhanced magnetic resonance study.” Eur J Vasc Endovasc Surg 35(4):392-8 Details

    Tang TY, Howarth SP, Miller SR, Graves MJ, U-King-Im JM, Li ZY, Walsh SR, Patterson AJ, Kirkpatrick PJ, Warburton EA, Varty K, Gaunt ME, Gillard JH (2008), “Correlation of carotid atheromatous plaque inflammation using USPIO-enhanced MR imaging with degree of luminal stenosis.” Stroke 39(7):2144-7 Details

    Tang TY, Moustafa RR, Howarth SP, Walsh SR, Boyle JR, Li ZY, Baron JC, Gillard JH, Warburton EA (2008), “Combined PET-FDG and USPIO-enhanced MR imaging in patients with symptomatic moderate carotid artery stenosis.” Eur J Vasc Endovasc Surg 36(1):53-5 Details

    Taviani V, Sutcliffe MP, Wong P, Li ZY, Young V, Graves MJ, Gillard JH (2008), “In vivo non-invasive high resolution MR-based method for the determination of the elastic modulus of arterial vessels.” Conf Proc IEEE Eng Med Biol Soc 2008:5569-72 Details

    Trivedi RA, Gillard JH, Kirkpatrick PJ (2008), “Modern methods for imaging carotid atheroma.” Br J Neurosurg 22(3):350-9 Details

    U-King-Im JM, Tang TY, Patterson A, Graves MJ, Howarth S, Li ZY, Trivedi R, Bowden D, Kirkpatrick PJ, Gaunt ME, Warburton EA, Antoun NM, Gillard JH (2008), “Characterisation of carotid atheroma in symptomatic and asymptomatic patients using high resolution MRI.” J Neurol Neurosurg Psychiatry 79(8):905-12 Details

    2007

    Gillard JH (2007), “Advances in atheroma imaging in the carotid.” Cerebrovasc Dis 24 Suppl 1:40-8 Details

    Howarth S, Li ZY, Trivedi RA, U-King-Im JM, Graves MJ, Kirkpatrick PJ, Gillard JH (2007), “Correlation of macrophage location and plaque stress distribution using USPIO-enhanced MRI in a patient with symptomatic severe carotid stenosis: a new insight into risk stratification.” Br J Neurosurg 21(4):396-8 Details

    Howarth SP, Tang TY, Graves MJ, U-King-Im JM, Li ZY, Walsh SR, Gaunt ME, Gillard JH (2007), “Non-invasive MR imaging of inflammation in a patient with both asymptomatic carotid atheroma and an abdominal aortic aneurysm: a case report.” Ann Surg Innov Res 1:4 Details

    Li ZY, Gillard JH (2007), “Simulation of the interaction between blood flow and atherosclerotic plaque.” Conf Proc IEEE Eng Med Biol Soc 2007:1699-702 Details

    Li ZY, Howarth S, Tang T, Graves M, U-King-Im J, Gillard JH (2007), “Does calcium deposition play a role in the stability of atheroma? Location may be the key.” Cerebrovasc Dis 24(5):452-9 Details

    Li ZY, Howarth SP, Tang T, Graves MJ, U-King-Im J, Trivedi RA, Kirkpatrick PJ, Gillard JH (2007), “Structural analysis and magnetic resonance imaging predict plaque vulnerability: a study comparing symptomatic and asymptomatic individuals.” J Vasc Surg 45(4):768-75 Details

    Müller K, Skepper JN, Posfai M, Trivedi R, Howarth S, Corot C, Lancelot E, Thompson PW, Brown AP, Gillard JH (2007), “Effect of ultrasmall superparamagnetic iron oxide nanoparticles (Ferumoxtran-10) on human monocyte-macrophages in vitro.” Biomaterials 28(9):1629-42 Details

    Newcombe VF, Williams GB, Nortje J, Bradley PG, Harding SG, Smielewski P, Coles JP, Maiya B, Gillard JH, Hutchinson PJ, Pickard JD, Carpenter TA, Menon DK (2007), “Analysis of acute traumatic axonal injury using diffusion tensor imaging.” Br J Neurosurg 21(4):340-8 Details

    Price SJ, Jena R, Burnet NG, Carpenter TA, Pickard JD, Gillard JH (2007), “Predicting patterns of glioma recurrence using diffusion tensor imaging.” Eur Radiol 17(7):1675-84 Details

    Price SJ, Jena R, Green HA, Kirkby NF, Lynch AG, Coles CE, Pickard JD, Gillard JH, Burnet NG (2007), “Early radiotherapy dose response and lack of hypersensitivity effect in normal brain tissue: a sequential dynamic susceptibility imaging study of cerebral perfusion.” Clin Oncol (R Coll Radiol) 19(8):577-87 Details

    Tang T, Walsh SR, Fanshawe TR, Gillard JH, Sadat U, Varty K, Gaunt ME, Boyle JR (2007), “Estimation of physiologic ability and surgical stress (E-PASS) as a predictor of immediate outcome after elective abdominal aortic aneurysm surgery.” Am J Surg 194(2):176-82 Details

    Tang TY, Howarth SP, Miller SR, Graves MJ, U-King-Im JM, Trivedi RA, Li ZY, Walsh SR, Brown AP, Kirkpatrick PJ, Gaunt ME, Gillard JH (2007), “Comparison of the inflammatory burden of truly asymptomatic carotid atheroma with atherosclerotic plaques contralateral to symptomatic carotid stenosis: an ultra small superparamagnetic iron oxide enhanced magnetic resonance study.” J Neurol Neurosurg Psychiatry 78(12):1337-43 Details

    Tang TY, Howarth SP, Walsh SR, Gaunt ME, Gillard JH (2007), “Contralateral carotid intraplaque hemorrhage may reduce the predictive value of fat-suppressed T1-weighted MRI in symptomatic carotid disease.” Stroke 38(12):e156-7; discussion e158-161 Details

    Tang TY, Walsh SR, Gillard JH, Varty K, Boyle JR, Gaunt ME (2007), “Carotid sinus nerve blockade to reduce blood pressure instability following carotid endarterectomy: a systematic review and meta-analysis.” Eur J Vasc Endovasc Surg 34(3):304-11 Details

    Trivedi RA, Li ZY, U-King-Im J, Graves MJ, Kirkpatrick PJ, Gillard JH (2007), “Identifying vulnerable carotid plaques in vivo using high resolution magnetic resonance imaging-based finite element analysis.” J Neurosurg 107(3):536-42 Details

    U-King-Im JM, Graves MJ, Cross JJ, Higgins NJ, Wat J, Trivedi RA, Tang T, Howarth SP, Kirkpatrick PJ, Antoun NM, Gillard JH (2007), “Internal carotid artery stenosis: accuracy of subjective visual impression for evaluation with digital subtraction angiography and contrast-enhanced MR angiography.” Radiology 244(1):213-22 Details

    U-King-Im JM, Tang T, Moustafa RR, Baron JC, Warburton EA, Gillard JH (2007), “Imaging the cellular biology of the carotid plaque.” Int J Stroke 2(2):85-96 Details

    2006

    Graves MJ, U-King-Im J, Howarth S, Gillard JH (2006), “Ultrafast magnetic resonance imaging protocols in stroke.” Expert Rev Neurother 6(6):921-30 Details

    Guadagno JV, Jones PS, Fryer TD, Barret O, Aigbirhio FI, Carpenter TA, Price CJ, Gillard JH, Warburton EA, Baron JC (2006), “Local relationships between restricted water diffusion and oxygen consumption in the ischemic human brain.” Stroke 37(7):1741-8 Details

    Guadagno JV, Warburton EA, Jones PS, Day DJ, Aigbirhio FI, Fryer TD, Harding S, Price CJ, Green HA, Barret O, Gillard JH, Baron JC (2006), “How affected is oxygen metabolism in DWI lesions?: A combined acute stroke PET-MR study.” Neurology 67(5):824-9 Details

    Hellier KD, Hampton JL, Guadagno JV, Higgins NP, Antoun NM, Day DJ, Gillard JH, Warburton EA, Baron JC (2006), “Perfusion CT helps decision making for thrombolysis when there is no clear time of onset.” J Neurol Neurosurg Psychiatry 77(3):417-9 Details

    Li ZY, Howarth S, Trivedi RA, U-King-Im JM, Graves MJ, Brown A, Wang L, Gillard JH (2006), “Stress analysis of carotid plaque rupture based on in vivo high resolution MRI.” J Biomech 39(14):2611-22 Details

    Li ZY, Howarth SP, Tang T, Gillard JH (2006), “How critical is fibrous cap thickness to carotid plaque stability? A flow-plaque interaction model.” Stroke 37(5):1195-9 Details

    Peña A, Green HA, Carpenter TA, Price SJ, Pickard JD, Gillard JH (2006), “Enhanced visualization and quantification of magnetic resonance diffusion tensor imaging using the p:q tensor decomposition.” Br J Radiol 79(938):101-9 Details

    Tang T, Howarth SP, Miller SR, Trivedi R, Graves MJ, King-Im JU, Li ZY, Brown AP, Kirkpatrick PJ, Gaunt ME, Gillard JH (2006), “Assessment of inflammatory burden contralateral to the symptomatic carotid stenosis using high-resolution ultrasmall, superparamagnetic iron oxide-enhanced MRI.” Stroke 37(9):2266-70 Details

    Trivedi RA, Mallawarachi C, U-King-Im JM, Graves MJ, Horsley J, Goddard MJ, Brown A, Wang L, Kirkpatrick PJ, Brown J, Gillard JH (2006), “Identifying inflamed carotid plaques using in vivo USPIO-enhanced MR imaging to label plaque macrophages.” Arterioscler Thromb Vasc Biol 26(7):1601-6 Details

    U-King-Im JM, Li ZY, Trivedi RA, Howarth S, Graves MJ, Kirkpatrick PJ, Gillard JH (2006), “Correlation of shear stress with carotid plaque rupture using MRI and finite element analysis.” J Neurol 253(3):379-81 Details

    2005

    Cunningham AS, Salvador R, Coles JP, Chatfield DA, Bradley PG, Johnston AJ, Steiner LA, Fryer TD, Aigbirhio FI, Smielewski P, Williams GB, Carpenter TA, Gillard JH, Pickard JD, Menon DK (2005), “Physiological thresholds for irreversible tissue damage in contusional regions following traumatic brain injury.” Brain 128(Pt 8):1931-42 Details

    Davies JR, Rudd JH, Fryer TD, Graves MJ, Clark JC, Kirkpatrick PJ, Gillard JH, Warburton EA, Weissberg PL (2005), “Identification of culprit lesions after transient ischemic attack by combined 18F fluorodeoxyglucose positron-emission tomography and high-resolution magnetic resonance imaging.” Stroke 36(12):2642-7 Details

    Guadagno JV, Warburton EA, Jones PS, Fryer TD, Day DJ, Gillard JH, Carpenter TA, Aigbirhio FI, Price CJ, Baron JC (2005), “The diffusion-weighted lesion in acute stroke: heterogeneous patterns of flow/metabolism uncoupling as assessed by quantitative positron emission tomography.” Cerebrovasc Dis 19(4):239-46 Details

    Jena R, Price SJ, Baker C, Jefferies SJ, Pickard JD, Gillard JH, Burnet NG (2005), “Diffusion tensor imaging: possible implications for radiotherapy treatment planning of patients with high-grade glioma.” Clin Oncol (R Coll Radiol) 17(8):581-90 Details

    Pickard JD, Gillard JH (2005), “Guidelines reduce the risk of brain-scan shock.” Nature 435(7038):17 Details

    Pickard JD, Hutchinson PJ, Coles JP, Steiner LA, Johnston AJ, Fryer TD, Coleman MR, Smielewski P, Chatfield DA, Aigbirhio F, Williams GB, Rice K, Clark JC, Salmond CH, Sahakian BJ, Bradley PG, Carpenter TA, Salvador R, Pena A, Gillard JH, Cunningham AS, Piechnik S, Czosnyka M, Menon DK (2005), “Imaging of cerebral blood flow and metabolism in brain injury in the ICU.” Acta Neurochir Suppl 95:459-64 Details

    Tasker RC, Salmond CH, Westland AG, Pena A, Gillard JH, Sahakian BJ, Pickard JD (2005), “Head circumference and brain and hippocampal volume after severe traumatic brain injury in childhood.” Pediatr Res 58(2):302-8 Details

    Tay KY, U-King-Im JM, Trivedi RA, Higgins NJ, Cross JJ, Davies JR, Weissberg PL, Antoun NM, Gillard JH (2005), “Imaging the vertebral artery.” Eur Radiol 15(7):1329-43 Details

    Tipper G, U-King-Im JM, Price SJ, Trivedi RA, Cross JJ, Higgins NJ, Farmer R, Wat J, Kirollos R, Kirkpatrick PJ, Antoun NM, Gillard JH (2005), “Detection and evaluation of intracranial aneurysms with 16-row multislice CT angiography.” Clin Radiol 60(5):565-72 Details

    Trivedi RA, Green HA, U-King-Im J, Graves M, Black R, Kirkpatrick PJ, Griffiths PD, Gillard JH (2005), “Cerebral haemodynamic disturbances in patients with moderate carotid artery stenosis.” Eur J Vasc Endovasc Surg 29(1):52-7 Details

    U-King-Im JM, Koo B, Trivedi RA, Higgins NJ, Tay KY, Cross JJ, Antoun NM, Gillard JH (2005), “Current diagnostic approaches to subarachnoid haemorrhage.” Eur Radiol 15(6):1135-47 Details

    U-King-Im JM, Trivedi RA, Graves MJ, Harkness K, Eales H, Joubert I, Koo B, Antoun N, Warburton EA, Gillard JH, Baron JC (2005), “Utility of an ultrafast magnetic resonance imaging protocol in recent and semi-recent strokes.” J Neurol Neurosurg Psychiatry 76(7):1002-5 Details

    2004

    Guadagno JV, Donnan GA, Markus R, Gillard JH, Baron JC (2004), “Imaging the ischaemic penumbra.” Curr Opin Neurol 17(1):61-7 Details

    Guadagno JV, Warburton EA, Aigbirhio FI, Smielewski P, Fryer TD, Harding S, Price CJ, Gillard JH, Carpenter TA, Baron JC (2004), “Does the acute diffusion-weighted imaging lesion represent penumbra as well as core? A combined quantitative PET/MRI voxel-based study.” J Cereb Blood Flow Metab 24(11):1249-54 Details

    Higgins JN, Gillard JH, Owler BK, Harkness K, Pickard JD (2004), “MR venography in idiopathic intracranial hypertension: unappreciated and misunderstood.” J Neurol Neurosurg Psychiatry 75(4):621-5 Details

    Price SJ, Peña A, Burnet NG, Jena R, Green HA, Carpenter TA, Pickard JD, Gillard JH (2004), “Tissue signature characterisation of diffusion tensor abnormalities in cerebral gliomas.” Eur Radiol 14(10):1909-17 Details

    Price SJ, Peña A, Burnet NG, Pickard JD, Gillard JH (2004), “Detecting glioma invasion of the corpus callosum using diffusion tensor imaging.” Br J Neurosurg 18(4):391-5 Details

    Trivedi RA, U-King-Im J, Graves MJ, Horsley J, Goddard M, Kirkpatrick PJ, Gillard JH (2004), “Multi-sequence in vivo MRI can quantify fibrous cap and lipid core components in human carotid atherosclerotic plaques.” Eur J Vasc Endovasc Surg 28(2):207-13 Details

    Trivedi RA, U-King-Im JM, Graves MJ, Cross JJ, Horsley J, Goddard MJ, Skepper JN, Quartey G, Warburton E, Joubert I, Wang L, Kirkpatrick PJ, Brown J, Gillard JH (2004), “In vivo detection of macrophages in human carotid atheroma: temporal dependence of ultrasmall superparamagnetic particles of iron oxide-enhanced MRI.” Stroke 35(7):1631-5 Details

    Trivedi RA, U-King-Im JM, Graves MJ, Horsley J, Goddard M, Kirkpatrick PJ, Gillard JH (2004), “MRI-derived measurements of fibrous-cap and lipid-core thickness: the potential for identifying vulnerable carotid plaques in vivo.” Neuroradiology 46(9):738-43 Details

    Trivedi RA, U-King-Im JM, Graves MJ, Kirkpatrick PJ, Gillard JH (2004), “Noninvasive imaging of carotid plaque inflammation.” Neurology 63(1):187-8 Details

    U-King-Im JM, Hollingworth W, Trivedi RA, Cross JJ, Higgins NJ, Graves MJ, Kirkpatrick PJ, Antoun NM, Gillard JH (2004), “Contrast-enhanced MR angiography vs intra-arterial digital subtraction angiography for carotid imaging: activity-based cost analysis.” Eur Radiol 14(4):730-5 Details

    U-King-Im JM, Trivedi R, Cross J, Higgins N, Graves M, Kirkpatrick P, Antoun N, Gillard JH (2004), “Conventional digital subtraction x-ray angiography versus magnetic resonance angiography in the evaluation of carotid disease: patient satisfaction and preferences.” Clin Radiol 59(4):358-63 Details

    U-King-Im JM, Trivedi RA, Cross JJ, Higgins NJ, Hollingworth W, Graves M, Joubert I, Kirkpatrick PJ, Antoun NM, Gillard JH (2004), “Measuring carotid stenosis on contrast-enhanced magnetic resonance angiography: diagnostic performance and reproducibility of 3 different methods.” Stroke 35(9):2083-8 Details

    U-King-Im JM, Trivedi RA, Graves MJ, Higgins NJ, Cross JJ, Tom BD, Hollingworth W, Eales H, Warburton EA, Kirkpatrick PJ, Antoun NM, Gillard JH (2004), “Contrast-enhanced MR angiography for carotid disease: diagnostic and potential clinical impact.” Neurology 62(8):1282-90 Details

    U-King-Im JM, Trivedi RA, Sala E, Graves MJ, Gaskarth M, Higgins NJ, Cross JC, Hollingworth W, Coulden RA, Kirkpatrick PJ, Antoun NM, Gillard JH (2004), “Evaluation of carotid stenosis with axial high-resolution black-blood MR imaging.” Eur Radiol 14(7):1154-61 Details

    2003

    Gillard JH (2003), “Imaging of carotid artery disease: from luminology to function?” Neuroradiology 45(10):671-80 Details

    Price SJ, Burnet NG, Donovan T, Green HA, Peña A, Antoun NM, Pickard JD, Carpenter TA, Gillard JH (2003), “Diffusion tensor imaging of brain tumours at 3T: a potential tool for assessing white matter tract invasion?” Clin Radiol 58(6):455-62 Details

    U-King-Im J, Trivedi R, Gillard JH (2003), “Contrast-enhanced magnetic resonance angiography carotid arteries.” Stroke 34(5):e15; author reply e15 Details

    Watts C, Donovan T, Gillard JH, Antoun NM, Burnstein R, Menon DK, Carpenter TA, Fryer T, Thomas DG, Pickard JD (2003), “Evaluation of an MRI-based protocol for cell implantation in four patients with Huntington's disease.” Cell Transplant 12(7):697-704 Details

    2002

    Gillard JH, Tom BD, Hollingworth W (2002), “Validation of the effectiveness and efficiency of newer techniques.” Radiology 223(2):586-7; author reply 587 Details

    Green HA, Peña A, Price CJ, Warburton EA, Pickard JD, Carpenter TA, Gillard JH (2002), “Increased anisotropy in acute stroke: a possible explanation.” Stroke 33(6):1517-21 Details

    Rosser AE, Barker RA, Harrower T, Watts C, Farrington M, Ho AK, Burnstein RM, Menon DK, Gillard JH, Pickard J, Dunnett SB, NEST-UK (2002), “Unilateral transplantation of human primary fetal tissue in four patients with Huntington's disease: NEST-UK safety report ISRCTN no 36485475.” J Neurol Neurosurg Psychiatry 73(6):678-85 Details

    Trivedi RA, Watts C, Kirkpatrick PJ, Gillard JH (2002), “Multiple cerebral aneurysms and the Diamond-Blackfan syndrome.” J Neurol Neurosurg Psychiatry 72(5):678-9 Details

    2001

    Gillard JH, Antoun NM, Burnet NG, Pickard JD (2001), “Reproducibility of quantitative CT perfusion imaging.” Br J Radiol 74(882):552-5 Details

    Gillard JH, Loneragan R, Cross J (2001), “Atypical aneurysms, vasculitis and stroke in systemic lupus erythematosus.” Br J Neurosurg 15(2):195-6 Details

    Gillard JH, Papadakis NG, Martin K, Price CJ, Warburton EA, Antoun NM, Huang CL, Carpenter TA, Pickard JD (2001), “MR diffusion tensor imaging of white matter tract disruption in stroke at 3 T.” Br J Radiol 74(883):642-7 Details

    2000

    Gillard JH (2000), “Systemic lupus with aneurysms.” J R Soc Med 93(3):160 Details

    Gillard JH, Dent TH, Smyth-Pigott PJ, Eaton J (2000), “Recent changes in the workload and clinical experience of pre-registration house officers: experiences over four years in south-west England.” Med Educ 34(5):371-3 Details

    Gillard JH, Minhas PS, Hayball MP, Bearcroft PW, Antoun NM, Freer CE, Mathews JC, Miles KA, Pickard JD (2000), “Assessment of quantitative computed tomographic cerebral perfusion imaging with H2(15)O positron emission tomography.” Neurol Res 22(5):457-64 Details

    1999

    Gillard JH, Hardingham CR, Antoun NM, Freer CE, Kirkpatrick PJ (1999), “Evaluation of carotid endarterectomy with sequential MR perfusion imaging: a preliminary 12-month follow up.” Clin Radiol 54(12):798-803 Details

    Murphy JM, Gomez-Anson B, Gillard JH, Antoun NM, Cross J, Elliott JD, Lockwood M (1999), “Wegener granulomatosis: MR imaging findings in brain and meninges.” Radiology 213(3):794-9 Details

    Razumovsky AY, Gillard JH, Bryan RN, Hanley DF, Oppenheimer SM (1999), “TCD, MRA and MRI in acute cerebral ischemia.” Acta Neurol Scand 99(1):65-76 Details

    1998

    Gillard JH, Hardingham CR, Kirkpatrick PJ, Antoun NM, Freer CE, Griffiths PD (1998), “Evaluation of carotid endarterectomy with sequential MR perfusion imaging: a preliminary report.” AJNR Am J Neuroradiol 19(9):1747-52 Details

    Gillard JH, Hubbard C, Das R, Sherriff H (1998), “Digital radiology in skeletal trauma: assessment of casualty officers' performance.” J R Soc Med 91(3):129-32 Details

    Gillard JH, Patel MC, Abrahams PH, Dixon AK (1998), “Riedel's lobe of the liver: fact or fiction?” Clin Anat 11(1):47-9 Details

    Gillard JH, Screaton NJ, Berman LH (1998), “Compression ultrasonography for diagnosing deep vein thrombosis. Other tests should not be abandoned.” BMJ 316(7143):1533; author reply 1535 Details

    Harrison RL, Gillard JH (1998), “Computed radiology.” AJR Am J Roentgenol 171(3):889-91 Details

    Screaton NJ, Gillard JH, Berman LH (1998), “The radiological investigation of suspected lower limb deep vein thrombosis.” Clin Radiol 53(5):388 Details

    Screaton NJ, Gillard JH, Berman LH, Kemp PM (1998), “Duplicated superficial femoral veins: a source of error in the sonographic investigation of deep vein thrombosis.” Radiology 206(2):397-401 Details

    Soher BJ, Gillard JH, Bryan RN, Oppenheimer SM, Barker PB (1998), “Magnetic resonance perfusion imaging in acute middle cerebral artery stroke: Comparison of blood volume and bolus peak arrival time.” J Stroke Cerebrovasc Dis 7(1):17-23 Details

    1997

    Gillard JH, Oliverio PJ, Barker PB, Oppenheimer SM, Bryan RN (1997), “MR angiography in acute cerebral ischemia of the anterior circulation: a preliminary report.” AJNR Am J Neuroradiol 18(2):343-50 Details

    1996

    Gillard JH, Barker PB, van Zijl PC, Bryan RN, Oppenheimer SM (1996), “Proton MR spectroscopy in acute middle cerebral artery stroke.” AJNR Am J Neuroradiol 17(5):873-86 Details

    1995

    Lee AG, Goldberg MF, Gillard JH, Barker PB, Bryan RN (1995), “Intracranial assessment of incontinentia pigmenti using magnetic resonance imaging, angiography, and spectroscopic imaging.” Arch Pediatr Adolesc Med 149(5):573-80 Details

    1994

    Barker PB, Gillard JH, van Zijl PC, Soher BJ, Hanley DF, Agildere AM, Oppenheimer SM, Bryan RN (1994), “Acute stroke: evaluation with serial proton MR spectroscopic imaging.” Radiology 192(3):723-32 Details

    1993

    Dent TH, Gillard JH (1993), “Cardiopulmonary resuscitation: effectiveness, training and survival.” J R Coll Physicians Lond 27(4):354-5 Details

    Dent TH, Gillard JH (1993), “Cardiopulmonary resuscitation. ...then retrained as often as necessary.” BMJ 307(6899):320-1 Details

    Gillard JH, Dent TH, Aarons EJ, Crimlisk HL, Smyth-Pigott PJ, Nicholls MW (1993), “Preregistration house officers in the Thames regions: changes in quality of training after four years.” BMJ 307(6913):1176-9 Details

    Gillard JH, Dent TH, Aarons EJ, Smyth-Pigott PJ, Nicholls MW (1993), “Preregistration house officers in eight English regions: survey of quality of training.” BMJ 307(6913):1180-4 Details

    Gillard JH, Dent TH, Hicks BH (1993), “Allocating pre-registration house officer posts.” Med Educ 27(4):390 Details

    Gillard JH, Dent TH, Jolly BC, Wallis DA, Hicks BH (1993), “CPR and the RCP (2). Training of students and doctors in UK medical schools.” J R Coll Physicians Lond 27(4):412-7 Details

    1992

    Gillard JH, Dent TH, Hicks BH (1992), “Allocation of junior hospital doctors to pre-registration posts: does Britain need a national matching scheme?” Med Educ 26(3):228-32 Details

    1990

    Dent TH, Gillard JH (1990), “The allocation of pre-registration house officer posts in the four Thames regions: a survey of house officer opinion.” Med Educ 24(6):535-9 Details

    Dent TH, Gillard JH, Aarons EJ, Crimlisk HL, Smyth-Pigott PJ (1990), “Preregistration house officers in the four Thames regions: II. Comparison of education and workload in teaching and non-teaching hospitals.” BMJ 300(6726):716-8 Details

    1988

    Gillard JH, Dent TH (1988), “The allocation of house officer posts: a UK survey.” Med Educ 22(4):342-4 Details

    1986

    Gillard JH, Kirkham FJ, Levin SD, Neville BG, Gosling RG (1986), “Anatomical validation of middle cerebral artery position as identified by transcranial pulsed Doppler ultrasound.” J Neurol Neurosurg Psychiatry 49(9):1025-9 Details