Dr Jane Risdall

Interests

In collaboration with DSTL Porton Down, I am looking at Blast Brain Injury in an animal model. Using a benchtop blast wave generator, I expose the cranium to a primary blast wave alone and subsequently look at changes in protein expression and gene activation in cerebral tissue. I am also looking for changes in brain protein expression in animals exposed to a systemic blast with accompanying polytrauma.

Research Focus

Keywords

Explosive Blast

Traumatic Brain Injury

Hypoxia

Imflammation

Cytokines

Clinical conditions

Traumatic brain injury

Equipment

Bench-top blast rig

Cytometric bead array

Immunohistochemistry

qRT PCR

Small animal model

Collaborators

Cambridge

David Menon

United Kingdom

Emrys Kirkman Web: http://ekirkman@dstl.gov.uk

Associated News Items


    Key publications

    Risdall JE, Menon DK (2011), “Traumatic brain injury.” Philos Trans R Soc Lond B Biol Sci 366(1562):241-50 PDF Details

    Publications

    2014

    Risdall JE, Carter AJ, Kirkman E, Watts SA, Taylor C, Menon DK (2014), “Endothelial Activation and Chemoattractant Expression are Early Processes in Isolated Blast Brain Injury.” Neuromolecular Med Details

    2013

    Hodkinson PD, Risdall JE (2013), “RE: Hernandez, R., Blanco, S., Peragon, J., Pedrosa, J. A., & Peinado, M. A. (2012). Hypobaric Hypoxia and Reoxygenation Induce Proteomic Profile Changes in the Rat Brain Cortex. Neuromolecular Medicine, doi:10.1007/s12017-012-8197-7.” Neuromolecular Med PDF Details

    Risdall JE, Carter AJ, Kirkman E, Watts SA, Taylor C, Menon DK (2013), “Endothelial activation and chemoattractant expression are early processes in isolated blast brain injury. ” Br J Anaesth 111(2): 314P-315P

    2011

    Risdall JE, Heames RM, Hill G (2011), “Role 2 afloat.” J R Army Med Corps 157(4):362-4 Details