Dr Jennifer Barnett

Jennifer Barnett

University position

Honorary Research Fellow

Departments

Department of Psychiatry

Home page

http://www.psychiatry.cam.ac.uk/

Research Themes

Cognitive and Behavioural Neuroscience

Clinical and Veterinary Neuroscience

Interests

I'm a psychologist and cognitive neuroscientist with some training in genetics and epidemiology. I’m interested in how genetic and environmental factors affect cognitive functions and mental health throughout life. This includes the development of relatively rare disorders such as schizophrenia as well as common ones such as anxiety, depression, and dementia. I’m involved in ongoing longitudinal studies including the Northern Finland Birth Cohorts and the UK National Survey of Health and Development where we are investigating how genetic and environmental influences develop and change across the lifecourse.

Research Focus

Keywords

schizophrenia

cognition

endophenotypes

neuropsychology

psychosis

Clinical conditions

Cognitive impairment

Depressive disorders

Schizophrenia

Equipment

Genetic Epidemiology

Neuropsychological testing

Collaborators

No collaborators listed

Key publications

Barnett JH, Robbins TW, Leeson VC, Sahakian BJ, Joyce EM, Blackwell AD (2010), “Assessing cognitive function in clinical trials of schizophrenia.” Neurosci Biobehav Rev 34(8):1161-77 Details

Barnett JH, Scoriels L, Munafò MR (2008), “Meta-analysis of the cognitive effects of the catechol-O-methyltransferase gene Val158/108Met polymorphism.” Biol Psychiatry 64(2):137-44 Details

Barnett JH, Heron J, Ring SM, Golding J, Goldman D, Xu K, Jones PB (2007), “Gender-specific effects of the catechol-O-methyltransferase Val108/158Met polymorphism on cognitive function in children.” Am J Psychiatry 164(1):142-9 Details

Publications

2013

Barnett JH, Hachinski V, Blackwell AD (2013), “Cognitive health begins at conception: addressing dementia as a lifelong and preventable condition.” BMC Med 11:246 Details

Gaysina D, Xu MK, Barnett JH, Croudace TJ, Wong A, Richards M, Jones PB, LHA genetics group (2013), “The catechol-O-methyltransferase gene (COMT) and cognitive function from childhood through adolescence.” Biol Psychol 92(2):359-64 Details

Jukuri T, Kiviniemi V, Nikkinen J, Miettunen J, Mäki P, Jääskeläinen E, Mukkala S, Koivukangas J, Nordström T, Taanila A, Moilanen I, Heinimaa M, Barnett JH, Jones PB, Murray GK, Veijola J (2013), “Default mode network in young people with familial risk for psychosis--the Oulu Brain and Mind study.” Schizophr Res 143(2-3):239-45 Details

McGrath LM, Cornelis MC, Lee PH, Robinson EB, Duncan LE, Barnett JH, Huang J, Gerber G, Sklar P, Sullivan P, Perlis RH, Smoller JW (2013), “Genetic predictors of risk and resilience in psychiatric disorders: A cross-disorder genome-wide association study of functional impairment in major depressive disorder, bipolar disorder, and schizophrenia.” Am J Med Genet B Neuropsychiatr Genet Details

Mukkala S, Ilonen T, Koskela J, Nordström T, Loukkola J, Miettunen J, Barnett JH, Murray GK, Jones PB, Heinimaa M, Jääskeläinen E, Mäki P, Moilanen I, Veijola J (2013), “Response initiation in young adults at risk for psychosis in the Northern Finland 1986 Birth Cohort.” Cogn Neuropsychiatry Details

Richards M, Barnett JH, Xu MK, Croudace TJ, Gaysina D, Kuh D, Jones PB, the MRC National Survey of Health and Development scientific and data collection team (2013), “Lifetime affect and midlife cognitive function: prospective birth cohort study.” Br J Psychiatry Details

Veijola J, Mäki P, Jääskeläinen E, Koivukangas J, Moilanen I, Taanila A, Nordström T, Hurtig T, Kiviniemi V, Mukkala S, Heinimaa M, Lindholm P, Jones PB, Barnett JH, Murray GK, Miettunen J (2013), “Young people at risk for psychosis: case finding and sample characteristics of the Oulu Brain and Mind Study.” Early Interv Psychiatry 7(2):146-54 Details

Xu MK, Jones PB, Barnett JH, Gaysina D, Kuh D, Croudace TJ, Richards M (2013), “Adolescent self-organization predicts midlife memory in a prospective birth cohort study.” Psychol Aging 28(4):958-68 Details

2012

Barnes A, Isohanni M, Barnett JH, Pietiläinen O, Veijola J, Miettunen J, Paunio T, Tanskanen P, Ridler K, Suckling J, Bullmore ET, Jones PB, Murray GK (2012), “Neuregulin-1 genotype is associated with structural differences in the normal human brain.” Neuroimage 59(3):2057-61 Details

Barnes A, Isohanni M, Barnett JH, Pietiläinen O, Veijola J, Miettunen J, Paunio T, Tanskanen P, Ridler K, Suckling J, Bullmore ET, Murray GK, Jones PB (2012), “No association of COMT (Val158Met) genotype with brain structure differences between men and women.” PLoS One 7(3):e33964 Details

Barnett JH, McDougall F, Xu MK, Croudace TJ, Richards M, Jones PB (2012), “Childhood cognitive function and adult psychopathology: associations with psychotic and non-psychotic symptoms in the general population.” Br J Psychiatry 201:124-30 Details

2011

Barnett JH, Huang J, Perlis RH, Young MM, Rosenbaum JF, Nierenberg AA, Sachs G, Nimgaonkar VL, Miklowitz DJ, Smoller JW (2011), “Personality and bipolar disorder: dissecting state and trait associations between mood and personality.” Psychol Med 41(8):1593-604 Details

Barnett JH, Xu K, Heron J, Goldman D, Jones PB (2011), “Cognitive effects of genetic variation in monoamine neurotransmitter systems: a population-based study of COMT, MAOA, and 5HTTLPR.” Am J Med Genet B Neuropsychiatr Genet 156(2):158-67 Details

Khandaker GM, Barnett JH, White IR, Jones PB (2011), “A quantitative meta-analysis of population-based studies of premorbid intelligence and schizophrenia.” Schizophr Res Details

Mukkala S, Ilonen T, Nordström T, Miettunen J, Loukkola J, Barnett JH, Murray GK, Jääskeläinen E, Mäki P, Taanila A, Moilanen I, Jones PB, Heinimaa M, Veijola J (2011), “Different vulnerability indicators for psychosis and their neuropsychological characteristics in the Northern Finland 1986 Birth Cohort.” J Clin Exp Neuropsychol 33(4):385-94 Details

Scoriels L, Barnett JH, Murray GK, Cherukuru S, Fielding M, Cheng F, Lennox BR, Sahakian BJ, Jones PB (2011), “Effects of modafinil on emotional processing in first episode psychosis.” Biol Psychiatry 69(5):457-64 Details

2010

Chamberlain SR, Robbins TW, Winder-Rhodes S, Müller U, Sahakian BJ, Blackwell AD, Barnett JH (2010), “Translational Approaches to Frontostriatal Dysfunction in Attention-Deficit/Hyperactivity Disorder Using a Computerized Neuropsychological Battery.” Biol Psychiatry Details

2009

Barnett JH, Heron J, Goldman D, Jones PB, Xu K (2009), “Effects of catechol-O-methyltransferase on normal variation in the cognitive function of children.” Am J Psychiatry 166(8):909-16 Details

Barnett JH, Smoller JW (2009), “The genetics of bipolar disorder.” Neuroscience 164(1):331-43 Details

2008

Murray GK, Cheng F, Clark L, Barnett JH, Blackwell AD, Fletcher PC, Robbins TW, Bullmore ET, Jones PB (2008), “Reinforcement and reversal learning in first-episode psychosis.” Schizophr Bull 34(5):848-55 Details

2007

Barnett JH, Croudace TJ, Jaycock S, Blackwell C, Hynes F, Sahakian BJ, Joyce EM, Jones PB (2007), “Improvement and decline of cognitive function in schizophrenia over one year: a longitudinal investigation using latent growth modelling.” BMC Psychiatry 7:16 Details

Barnett JH, Jones PB, Robbins TW, Müller U (2007), “Effects of the catechol-O-methyltransferase Val158Met polymorphism on executive function: a meta-analysis of the Wisconsin Card Sort Test in schizophrenia and healthy controls.” Mol Psychiatry 12(5):502-9 Details

Barnett JH, Werners U, Secher SM, Hill KE, Brazil R, Masson K, Pernet DE, Kirkbride JB, Murray GK, Bullmore ET, Jones PB (2007), “Substance use in a population-based clinic sample of people with first-episode psychosis.” Br J Psychiatry 190:515-20 Details

2006

Barnett JH, Salmond CH, Jones PB, Sahakian BJ (2006), “Cognitive reserve in neuropsychiatry.” Psychol Med 36(8):1053-64 Details

2005

Barnett JH, Sahakian BJ, Werners U, Hill KE, Brazil R, Gallagher O, Bullmore ET, Jones PB (2005), “Visuospatial learning and executive function are independently impaired in first-episode psychosis.” Psychol Med 35(7):1031-41 Details