Dr Jennifer Barnett
University position
Honorary Research Fellow
Departments
Home page
http://www.psychiatry.cam.ac.uk/
Research Themes
Interests
I'm a psychologist and cognitive neuroscientist with some training in genetics and epidemiology. I’m interested in how genetic and environmental factors affect cognitive functions and mental health throughout life. This includes the development of relatively rare disorders such as schizophrenia as well as common ones such as anxiety, depression, and dementia. I’m involved in ongoing longitudinal studies including the Northern Finland Birth Cohorts and the UK National Survey of Health and Development where we are investigating how genetic and environmental influences develop and change across the lifecourse.
Research Focus
Keywordsschizophrenia cognition endophenotypes neuropsychology psychosis |
Clinical conditionsCognitive impairment Depressive disorders Schizophrenia |
Equipment
Genetic Epidemiology
Neuropsychological testing
Collaborators
No collaborators listed
Key publications
Barnett JH, Robbins TW, Leeson VC, Sahakian BJ, Joyce EM, Blackwell AD (2010), “Assessing cognitive function in clinical trials of schizophrenia.” Neurosci Biobehav Rev 34(8):1161-77 Details
Barnett JH, Scoriels L, Munafò MR (2008), “Meta-analysis of the cognitive effects of the catechol-O-methyltransferase gene Val158/108Met polymorphism.” Biol Psychiatry 64(2):137-44 Details
Barnett JH, Heron J, Ring SM, Golding J, Goldman D, Xu K, Jones PB (2007), “Gender-specific effects of the catechol-O-methyltransferase Val108/158Met polymorphism on cognitive function in children.” Am J Psychiatry 164(1):142-9 Details
Publications
2012
Barnes A, Isohanni M, Barnett JH, Pietiläinen O, Veijola J, Miettunen J, Paunio T, Tanskanen P, Ridler K, Suckling J, Bullmore ET, Jones PB, Murray GK (2012), “Neuregulin-1 genotype is associated with structural differences in the normal human brain.” Neuroimage 59(3):2057-61 Details
Barnes A, Isohanni M, Barnett JH, Pietiläinen O, Veijola J, Miettunen J, Paunio T, Tanskanen P, Ridler K, Suckling J, Bullmore ET, Murray GK, Jones PB (2012), “No association of COMT (Val158Met) genotype with brain structure differences between men and women.” PLoS One 7(3):e33964 Details
Barnett JH, McDougall F, Xu MK, Croudace TJ, Richards M, Jones PB (2012), “Childhood cognitive function and adult psychopathology: associations with psychotic and non-psychotic symptoms in the general population.” Br J Psychiatry Details
Veijola J, Mäki P, Jääskeläinen E, Koivukangas J, Moilanen I, Taanila A, Nordström T, Hurtig T, Kiviniemi V, Mukkala S, Heinimaa M, Lindholm P, Jones PB, Barnett JH, Murray GK, Miettunen J (2012), “Young people at risk for psychosis: case finding and sample characteristics of the Oulu Brain and Mind Study.” Early Interv Psychiatry Details
2011
Barnett JH, Huang J, Perlis RH, Young MM, Rosenbaum JF, Nierenberg AA, Sachs G, Nimgaonkar VL, Miklowitz DJ, Smoller JW (2011), “Personality and bipolar disorder: dissecting state and trait associations between mood and personality.” Psychol Med 41(8):1593-604 Details
Barnett JH, Xu K, Heron J, Goldman D, Jones PB (2011), “Cognitive effects of genetic variation in monoamine neurotransmitter systems: a population-based study of COMT, MAOA, and 5HTTLPR.” Am J Med Genet B Neuropsychiatr Genet 156(2):158-67 Details
Khandaker GM, Barnett JH, White IR, Jones PB (2011), “A quantitative meta-analysis of population-based studies of premorbid intelligence and schizophrenia.” Schizophr Res Details
Mukkala S, Ilonen T, Nordström T, Miettunen J, Loukkola J, Barnett JH, Murray GK, Jääskeläinen E, Mäki P, Taanila A, Moilanen I, Jones PB, Heinimaa M, Veijola J (2011), “Different vulnerability indicators for psychosis and their neuropsychological characteristics in the Northern Finland 1986 Birth Cohort.” J Clin Exp Neuropsychol 33(4):385-94 Details
Scoriels L, Barnett JH, Murray GK, Cherukuru S, Fielding M, Cheng F, Lennox BR, Sahakian BJ, Jones PB (2011), “Effects of modafinil on emotional processing in first episode psychosis.” Biol Psychiatry 69(5):457-64 Details
2010
Chamberlain SR, Robbins TW, Winder-Rhodes S, Müller U, Sahakian BJ, Blackwell AD, Barnett JH (2010), “Translational Approaches to Frontostriatal Dysfunction in Attention-Deficit/Hyperactivity Disorder Using a Computerized Neuropsychological Battery.” Biol Psychiatry Details
2009
Barnett JH, Heron J, Goldman D, Jones PB, Xu K (2009), “Effects of catechol-O-methyltransferase on normal variation in the cognitive function of children.” Am J Psychiatry 166(8):909-16 Details
Barnett JH, Smoller JW (2009), “The genetics of bipolar disorder.” Neuroscience 164(1):331-43 Details
2008
Murray GK, Cheng F, Clark L, Barnett JH, Blackwell AD, Fletcher PC, Robbins TW, Bullmore ET, Jones PB (2008), “Reinforcement and reversal learning in first-episode psychosis.” Schizophr Bull 34(5):848-55 Details
2007
Barnett JH, Croudace TJ, Jaycock S, Blackwell C, Hynes F, Sahakian BJ, Joyce EM, Jones PB (2007), “Improvement and decline of cognitive function in schizophrenia over one year: a longitudinal investigation using latent growth modelling.” BMC Psychiatry 7:16 Details
Barnett JH, Jones PB, Robbins TW, Müller U (2007), “Effects of the catechol-O-methyltransferase Val158Met polymorphism on executive function: a meta-analysis of the Wisconsin Card Sort Test in schizophrenia and healthy controls.” Mol Psychiatry 12(5):502-9 Details
Barnett JH, Werners U, Secher SM, Hill KE, Brazil R, Masson K, Pernet DE, Kirkbride JB, Murray GK, Bullmore ET, Jones PB (2007), “Substance use in a population-based clinic sample of people with first-episode psychosis.” Br J Psychiatry 190:515-20 Details
2006
Barnett JH, Salmond CH, Jones PB, Sahakian BJ (2006), “Cognitive reserve in neuropsychiatry.” Psychol Med 36(8):1053-64 Details
2005
Barnett JH, Sahakian BJ, Werners U, Hill KE, Brazil R, Gallagher O, Bullmore ET, Jones PB (2005), “Visuospatial learning and executive function are independently impaired in first-episode psychosis.” Psychol Med 35(7):1031-41 Details
Research and Collaboration
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