Dr Jennifer Murray

Interests

My research primarily involves mapping the striatal circuitry responsible for the transition from goal-directed to habitual drug seeking.

Research Focus

Keywords

addiction

learning

compulsivity

impulsivity

dopamine

Clinical conditions

Addiction

Attention deficit hyperactivity disorder

Cognitive impairment

Obsessive compulsive disorder

Equipment

Behavioural analysis

Collaborators

Cambridge

David Belin

Jeff Dalley

Barry Everitt

International

Yann Pelloux

Associated News Items


Publications

2016

Jupp B, Murray JE, Jordan ER, Xia J, Fluharty M, Shrestha S, Robbins TW, Dalley JW (2016), “Social dominance in rats predicts cocaine self-administration, novelty reactivity and altered dopamine receptor binding and content in the striatum.” Psychopharmacology 233: 579-589

2015

Ducret E, Puaud M, Lacoste J, Dugast E, Belin-Rauscent A, Murray JE, Everitt BJ, Houeto J-L, Belin D (2015), “N-acetylcysteine facilitates self-imposed abstinence after escalation of cocaine intake.” Biol Psychiatry

Murray JE, Belin-Rauscent A, Simon M, Giuliano C, Benoît-Marand M, Everitt BJ, Belin D (2015), “Basolateral and central amygdala differentially recruit and maintain dorsolateral striatum-dependent cocaine-seeking habits.” Nat Commun

Pelloux Y, Murray JE, Everitt BJ (2015), “Differential vulnerability to the punishment of cocaine related behaviours: effects of locus of punishment, cocaine taking history and alternative reinforcer availability.” Psychopharmacology (Berl) 232(1):125-34 Details

2014

Murray JE, Dilleen R, Pelloux Y, Economidou D, Dalley JW, Belin D, Everitt BJ (2014), “Increased impulsivity retards the transition to dorsolateral striatal dopamine control of cocaine seeking.” Biol Psychiatry 76(1):15-22 Details

2013

Belin D, Belin-Rauscent A, Murray JE, Everitt BJ (2013), “Addiction: failure of control over maladaptive incentive habits.” Curr Opin Neurobiol 23(4):564-72 Details

Fernando AB, Murray JE, Milton AL (2013), “The amygdala: securing pleasure and avoiding pain.” Front Behav Neurosci 7:190 Details

Pelloux Y, Murray JE, Everitt BJ (2013), “Differential roles of the prefrontal cortical subregions and basolateral amygdala in compulsive cocaine seeking and relapse after voluntary abstinence in rats.” Eur J Neurosci Details

2012

Murray JE, Belin D, Everitt BJ (2012), “Double dissociation of the dorsomedial and dorsolateral striatal control over the acquisition and performance of cocaine seeking.” Neuropsychopharmacology 37(11):2456-66 Details

Murray JE, Everitt BJ, Belin D (2012), “N-Acetylcysteine reduces early- and late-stage cocaine seeking without affecting cocaine taking in rats.” Addict Biol 17(2):437-40 Details

Murray JE, Lacoste J, Belin D (2012), “N-Acetylcysteine as a Treatment for Addiction.” In: D Belin (Ed.) Addictions – From Pathophysiology to Treatment Intech (pp. 355-380)

Murray JE, Polewan RJ, Bevins RA (2012), “Rethinking the nicotine stimulus” In: JE Murray (Ed) Exposure Therapy: New Developments. Hauppauge, NY: Nova Science Publishers, Inc (pp. 95-120)

2011

Bevins RA, Murray JE (2011), “Internal stimuli generated by abused substances: Role of Pavlovian conditioning and its implications for drug addiction.” In: TR Schachtman & S Reilly (Eds) Associative Learning and Conditioning: Human and Non-Human Applications New York, NY: Oxford University Press (pp. 270-289)

Murray JE, Bevins RA (2011), “Excitatory conditioning to the interoceptive nicotine stimulus blocks subsequent conditioning to an exteroceptive light stimulus.” Behav Brain Res 221(1):314-9 Details

Murray JE, Walker AW, Li C, Wells NR, Penrod RD, Bevins RA (2011), “Nicotine trained as a negative feature passes the retardation-of-acquisition and summation tests of a conditioned inhibitor.” Learn Mem 18(7):452-8 Details

Murray JE, Walker AW, Polewan RJ, Bevins RA (2011), “An examination of NMDA receptor contribution to conditioned responding evoked by the conditional stimulus effects of nicotine.” Psychopharmacology (Berl) 213(1):131-41 Details

Murray JE, Wells NR, Bevins RA (2011), “Nicotine competes with a visual stimulus for control of conditioned responding.” Addict Biol 16(1):152-62 Details

2010

Murray JE, Bevins RA (2010), “Cannabinoid conditioned reward and aversion: behavioral and neural processes.” ACS Chem Neurosci 1(4):265-278 Details

Reichel CM, Murray JE, Barr JD, Bevins RA (2010), “Extinction with varenicline and nornicotine, but not ABT-418, weakens conditioned responding evoked by the interoceptive stimulus effects of nicotine.” Neuropharmacology 58(8):1237-45 Details

2009

Duryee MJ, Bevins RA, Reichel CM, Murray JE, Dong Y, Thiele GM, Sanderson SD (2009), “Immune responses to methamphetamine by active immunization with peptide-based, molecular adjuvant-containing vaccines.” Vaccine 27(22):2981-8 Details

Murray JE, Bevins RA (2009), “Acquired appetitive responding to intravenous nicotine reflects a Pavlovian conditioned association.” Behav Neurosci 123(1):97-108 Details

Murray JE, Penrod RD, Bevins RA (2009), “Nicotine-evoked conditioned responding is dependent on concentration of sucrose unconditioned stimulus.” Behav Processes 81(1):136-9 Details

Murray JE, Wells NR, Lyford GD, Bevins RA (2009), “Investigation of endocannabinoid modulation of conditioned responding evoked by a nicotine CS and the Pavlovian stimulus effects of CP 55,940 in adult male rats.” Psychopharmacology (Berl) 205(4):655-65 Details

Reichel CM, Murray JE, Grant KM, Bevins RA (2009), “Bupropion attenuates methamphetamine self-administration in adult male rats.” Drug Alcohol Depend 100(1-2):54-62 Details

2007

Murray JE, Bevins RA (2007), “The conditional stimulus effects of nicotine vary as a function of training dose.” Behav Pharmacol 18(8):707-16 Details

Murray JE, Bevins RA (2007), “Behavioral and neuropharmacological characterization of nicotine as a conditional stimulus.” Eur J Pharmacol 561(1-3):91-104 Details

Murray JE, Li C, Palmatier MI, Bevins RA (2007), “The interoceptive Pavlovian stimulus effects of caffeine.” Pharmacol Biochem Behav 86(4):838-46 Details

2006

Wilkinson JL, Murray JE, Li C, Wiltgen SM, Penrod RD, Berg SA, Bevins RA (2006), “Interoceptive Pavlovian conditioning with nicotine as the conditional stimulus varies as a function of the number of conditioning trials and unpaired sucrose deliveries.” Behav Pharmacol 17(2):161-72 Details

2005

Briner W, Murray J (2005), “Effects of short-term and long-term depleted uranium exposure on open-field behavior and brain lipid oxidation in rats.” Neurotoxicol Teratol 27(1):135-44 Details