Dr James Kirkbride Ph.D.

James Kirkbride

University position

Sir Henry Dale Fellow

Departments

Department of Psychiatry

Email

jbk25@cam.ac.uk

Home page

http://www.sepea.org

Research Theme

Cognitive and Behavioural Neuroscience

Interests

Please note, from 1 January 2014 I will relocate to UCL, Division of Psychiatry. I will continue to collaborate with the Department of Psychiatry, University of Cambridge, on the SEPEA and EU-GEI studies.

I am a psychiatric epidemiologist interested in the causes of schizophrenia and other major psychotic disorders from an environmental perspective. I am particularly interested in the interplay between genes and environment to lead to the onset of psychosis via disruption of neurobiological pathways. My current research involves investigating the incidence of psychotic disorders in East Anglia - an area with marked variation in deprivation, immigration and population density.

The SEPEA study - developing effective mental health service provision in rural areas
The SEPEA study - developing effective mental health service provision in rural areas
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Research Focus

Keywords

epidemiology

public health

psychosis

environment

social psychiatry

Clinical conditions

Bipolar disorder

Depressive disorders

Schizophrenia

Equipment

GIS

hierarchical Bayesian modelling

multilevel statistical modelling

Poisson regression

spatial epidemiology

Collaborators

Cambridge

Peter Jones

United Kingdom

Jeremey Coid Web: http://www.wolfson.qmul.ac.uk/psychia...

Robin Murray Web: http://www.iop.kcl.ac.uk/staff/p...

International

Ezra Susser Web: http://asp.cumc.columbia.edu/facdb/p...

Andrei Szoke Web: http://www.schizophreniaforum.org/com/res...

Jim van Os Web: http://mhens.unimaas.nl/index.p...

Associated News Items


    Key publications

    Kirkbride JB, Jackson D, Perez J, Fowler D, Winton F, Coid JW, Murray RM, Jones PB (2013), “A population-level prediction tool for the incidence of first-episode psychosis: translational epidemiology based on cross-sectional data.” BMJ Open 3(2) Details

    Kirkbride JB, Errazuriz A, Croudace TJ, Morgan C, Jackson D, Boydell J, Murray RM, Jones PB (2012), “Incidence of schizophrenia and other psychoses in England, 1950-2009: a systematic review and meta-analyses.” PLoS One 7(3):e31660 Details

    Kirkbride JB, Jones PB, Ullrich S, Coid JW (2012), “Social Deprivation, Inequality, and the Neighborhood-Level Incidence of Psychotic Syndromes in East London.” Schizophr Bull Details

    Cheng F, Kirkbride JB, Lennox BR, Perez J, Masson K, Lawrence K, Hill K, Feeley L, Painter M, Murray GK, Gallagher O, Bullmore ET, Jones PB (2011), “Administrative incidence of psychosis assessed in an early intervention service in England: first epidemiological evidence from a diverse, rural and urban setting.” Psychol Med 41(5):949-58 PDF Details

    Kirkbride JB, Croudace T, Brewin J, Donoghue K, Mason P, Glazebrook C, Medley I, Harrison G, Cooper JE, Doody GA, Jones PB (2009), “Is the incidence of psychotic disorder in decline? Epidemiological evidence from two decades of research.” Int J Epidemiol 38(5):1255-64 PDF Details

    Coid JW, Kirkbride JB, Barker D, Cowden F, Stamps R, Yang M, Jones PB (2008), “Raised incidence rates of all psychoses among migrant groups: findings from the East London first episode psychosis study.” Arch Gen Psychiatry 65(11):1250-8 PDF Details

    Kirkbride JB, Barker D, Cowden F, Stamps R, Yang M, Jones PB, Coid JW (2008), “Psychoses, ethnicity and socio-economic status.” Br J Psychiatry 193(1):18-24 PDF Details

    Kirkbride JB, Boydell J, Ploubidis GB, Morgan C, Dazzan P, McKenzie K, Murray RM, Jones PB (2008), “Testing the association between the incidence of schizophrenia and social capital in an urban area.” Psychol Med 38(8):1083-94 PDF Details

    March D, Hatch SL, Morgan C, Kirkbride JB, Bresnahan M, Fearon P, Susser E (2008), “Psychosis and place.” Epidemiol Rev 30:84-100 Details

    Kirkbride JB, Fearon P, Morgan C, Dazzan P, Morgan K, Tarrant J, Lloyd T, Holloway J, Hutchinson G, Leff JP, Mallett RM, Harrison GL, Murray RM, Jones PB (2006), “Heterogeneity in incidence rates of schizophrenia and other psychotic syndromes: findings from the 3-center AeSOP study.” Arch Gen Psychiatry 63(3):250-8 PDF Details

    Publications

    2014

    Kirkbride JB (2014), “Hitting the floor: Understanding migration patterns following the first episode of psychosis.” Health Place 28:150-2 Details

    Morgan C, Reininghaus U, Fearon P, Hutchinson G, Morgan K, Dazzan P, Boydell J, Kirkbride JB, Doody GA, Jones PB, Murray RM, Craig T (2014), “Modelling the interplay between childhood and adult adversity in pathways to psychosis: initial evidence from the AESOP study.” Psychol Med 44(2):407-19 Details

    Oher FJ, Demjaha A, Jackson D, Morgan C, Dazzan P, Morgan K, Boydell J, Doody GA, Murray RM, Bentall RP, Jones PB, Kirkbride JB (2014), “The effect of the environment on symptom dimensions in the first episode of psychosis: a multilevel study.” Psychol Med :1-12 Details

    Szöke A, Kirkbride JB, Schürhoff F (2014), “Universal prevention of schizophrenia and surrogate endpoints at population level.” Soc Psychiatry Psychiatr Epidemiol Details

    2013

    Jackson D, Kirkbride J, Croudace T, Morgan C, Boydell J, Errazuriz A, Murray RM, Jones PB (2013), “Meta-analytic approaches to determine gender differences in the age-incidence characteristics of schizophrenia and related psychoses.” Int J Methods Psychiatr Res 22(1):36-45 Details

    Kirkbride JB, Jones PB (2013), “Parity of esteem begins at home: translating empirical psychiatric research into effective public mental health.” Psychol Med :1-8 Details

    Omer S, Kirkbride JB, Pringle DG, Russell V, O'Callaghan E, Waddington JL (2013), “Neighbourhood-level socio-environmental factors and incidence of first episode psychosis by place at onset in rural Ireland: The Cavan-Monaghan First Episode Psychosis Study [CAMFEPS].” Schizophr Res Details

    2012

    Khandaker GM, Kirkbride JB, Jones PB (2012), “Epidemiological challenges in systematic reviews.” Br J Psychiatry 201(3):248 Details

    Kirkbride JB, Stubbins C, Jones PB (2012), “Psychosis incidence through the prism of early intervention services.” Br J Psychiatry 200(2):156-7 Details

    Kirkbride JB, Susser E, Kundakovic M, Kresovich JK, Davey Smith G, Relton CL (2012), “Prenatal nutrition, epigenetics and schizophrenia risk: can we test causal effects?” Epigenomics 4(3):303-15 Details

    2011

    Bhugra D, Gupta S, Bhui K, Craig T, Dogra N, Ingleby JD, Kirkbride J, Moussaoui D, Nazroo J, Qureshi A, Stompe T, Tribe R (2011), “WPA guidance on mental health and mental health care in migrants.” World Psychiatry 10(1):2-10 PDF Details

    Kirkbride JB (2011), “Incident cannabis use in adolescents and young adults is associated with an increased risk of developing psychotic symptoms.” Evid Based Ment Health 14(3):70 Details

    Kirkbride JB, Jones PB (2011), “The prevention of schizophrenia--what can we learn from eco-epidemiology?” Schizophr Bull 37(2):262-71 PDF Details

    2010

    Kirkbride J, Coid JW, Morgan C, Fearon P, Dazzan P, Yang M, Lloyd T, Harrison GL, Murray RM, Jones PB (2010), “Translating the epidemiology of psychosis into public mental health: evidence, challenges and future prospects.” J Public Ment Health 9(2):4-14 PDF Details

    Kirkbride JB, Lunn DJ, Morgan C, Lappin JM, Dazzan P, Morgan K, Fearon P, Murray RM, Jones PB (2010), “Examining evidence for neighbourhood variation in the duration of untreated psychosis.” Health Place 16(2):219-225 PDF Details

    Paton C, Barnes TR, Shingleton-Smith A, McAllister-Williams RH, Kirkbride J, Jones PB, McIntyre S (2010), “Lithium in bipolar and other affective disorders: prescribing practice in the UK.” J Psychopharmacol Details

    2009

    Hickman M, Vickerman P, Macleod J, Lewis G, Zammit S, Kirkbride J, Jones P (2009), “If cannabis caused schizophrenia--how many cannabis users may need to be prevented in order to prevent one case of schizophrenia? England and Wales calculations.” Addiction 104(11):1856-61 Details

    Ihara K, Morgan C, Fearon P, Dazzan P, Demjaha A, Lloyd T, Kirkbride JB, Hayhurst H, Murray RM, Jones PB (2009), “The prevalence, diagnostic significance and demographic characteristics of Schneiderian first-rank symptoms in an epidemiological sample of first-episode psychoses.” Psychopathology 42(2):81-91 Details

    Kirkbride JB, Scoriels L (2009), “Review of the 6th symposium for the search for the causes of schizophrenia, Sao Paulo, Brazil, 3-6 February 2009.” Eur Arch Psychiatry Clin Neurosci 259(8):505-9 Details

    Morgan C, Fisher H, Hutchinson G, Kirkbride J, Craig TK, Morgan K, Dazzan P, Boydell J, Doody GA, Jones PB, Murray RM, Leff J, Fearon P (2009), “Ethnicity, social disadvantage and psychotic-like experiences in a healthy population based sample.” Acta Psychiatr Scand 119(3):226-35 Details

    2008

    Morgan C, Kirkbride J, Hutchinson G, Craig T, Morgan K, Dazzan P, Boydell J, Doody GA, Jones PB, Murray RM, Leff J, Fearon P (2008), “Cumulative social disadvantage, ethnicity and first-episode psychosis: a case-control study.” Psychol Med 38(12):1701-15 Details

    2007

    Barnett JH, Werners U, Secher SM, Hill KE, Brazil R, Masson K, Pernet DE, Kirkbride JB, Murray GK, Bullmore ET, Jones PB (2007), “Substance use in a population-based clinic sample of people with first-episode psychosis.” Br J Psychiatry 190:515-20 Details

    Hickman M, Vickerman P, Macleod J, Kirkbride J, Jones PB (2007), “Cannabis and schizophrenia: model projections of the impact of the rise in cannabis use on historical and future trends in schizophrenia in England and Wales.” Addiction 102(4):597-606 Details

    Kirkbride JB, Fearon P, Morgan C, Dazzan P, Morgan K, Murray RM, Jones PB (2007), “Neighbourhood variation in the incidence of psychotic disorders in Southeast London.” Soc Psychiatry Psychiatr Epidemiol 42(6):438-45 Details

    Kirkbride JB, Morgan C, Fearon P, Dazzan P, Murray RM, Jones PB (2007), “Neighbourhood-level effects on psychoses: re-examining the role of context.” Psychol Med 37(10):1413-25 Details

    Morgan C, Kirkbride J, Leff J, Craig T, Hutchinson G, McKenzie K, Morgan K, Dazzan P, Doody GA, Jones P, Murray R, Fearon P (2007), “Parental separation, loss and psychosis in different ethnic groups: a case-control study.” Psychol Med 37(4):495-503 Details

    2006

    Fearon P, Kirkbride JB, Morgan C, Dazzan P, Morgan K, Lloyd T, Hutchinson G, Tarrant J, Fung WL, Holloway J, Mallett R, Harrison G, Leff J, Jones PB, Murray RM, AESOP Study Group (2006), “Incidence of schizophrenia and other psychoses in ethnic minority groups: results from the MRC AESOP Study.” Psychol Med 36(11):1541-50 Details

    2005

    Boyle A, Kirkbride J, Jones P (2005), “Record linkage of domestic assault victims between an emergency department and the police.” J Epidemiol Community Health 59(10):909-10 Details

    Lloyd T, Kennedy N, Fearon P, Kirkbride J, Mallett R, Leff J, Holloway J, Harrison G, Dazzan P, Morgan K, Murray RM, Jones PB, AESOP study team (2005), “Incidence of bipolar affective disorder in three UK cities: results from the AESOP study.” Br J Psychiatry 186:126-31 Details