Dr Julia Deakin
I plan to experiment with brain imaging techniques and immunomics to look for early changes in psychosis. In particular, I am interested in supporting a recently identified group of patients with psychosis who have autoantibodies to the NMDA receptor or the VGKC receptor. I aim to understand the pathophysiology in order to further develop rational approaches to treatment. NARSAD has kindly provided funds for imaging in early psychosis.
Before qualifying in medicine, my research focused on the effects of pharmacological manipulations on impulsive decision making.
Cross-sectional and cohort studies
Associated News Items
Auyeung B, Lombardo MV, Heinrichs M, Chakrabarti B, Sule A, Deakin JB, Bethlehem RA, Dickens L, Mooney N, Sipple JA, Thiemann P, Baron-Cohen S (2015), “Oxytocin increases eye contact during a real-time, naturalistic social interaction in males with and without autism.” Transl Psychiatry 5:e507 Details
Khandakher G, Cousins L, Deakin JB, Lennox, Yolken R, Jones PB (2015), “Inflammation and immunity in schizophrenia: implications for pathophysiology and treatment ” Lancet Psychiatry
Deakin J, Lennox BR, Zandi MS (2014), “Antibodies to the N-methyl-d-aspartate receptor and other synaptic proteins in psychosis.” Biol Psychiatry 75(4):284-91 Details
Zandi MS, Deakin JB, Morris K, Buckley C, Jacobson L, Scoriels L, Cox AL, Coles AJ, Jones PB, Vincent A, Lennox BR (2014), “Immunotherapy for patients with acute psychosis and serum N-Methyl D-Aspartate receptor (NMDAR) antibodies: a description of a treated case series.” Schizophr Res 160(1-3):193-5 Details
Deakin J, Lennox B (2013), “Psychotic symptoms in young people warrant urgent referral.” Practitioner 257(1759):25-8, 3 Details
Deakin J, O'Loughlin C (2009), “STAR*D: a summary and UK perspective.” J Psychopharmacol 23(6):605-12 Details
Chamberlain SR, Müller U, Deakin JB, Corlett PR, Dowson J, Cardinal RN, Aitken MR, Robbins TW, Sahakian BJ (2007), “Lack of deleterious effects of buspirone on cognition in healthy male volunteers.” J Psychopharmacol 21(2):210-5 Details
Ersche KD, Fletcher PC, Lewis SJ, Clark L, Stocks-Gee G, London M, Deakin JB, Robbins TW, Sahakian BJ (2005), “Abnormal frontal activations related to decision-making in current and former amphetamine and opiate dependent individuals.” Psychopharmacology (Berl) 180(4):612-23 Details
Deakin J, Aitken M, Robbins T, Sahakian BJ (2004), “Risk taking during decision-making in normal volunteers changes with age.” J Int Neuropsychol Soc 10(4):590-8 Details
Deakin JB, Aitken MR, Dowson JH, Robbins TW, Sahakian BJ (2004), “Diazepam produces disinhibitory cognitive effects in male volunteers.” Psychopharmacology (Berl) 173(1-2):88-97 Details
Deakin JB, Rahman S, Nestor PJ, Hodges JR, Sahakian BJ (2004), “Paroxetine does not improve symptoms and impairs cognition in frontotemporal dementia: a double-blind randomized controlled trial.” Psychopharmacology (Berl) 172(4):400-8 Details