Professor Ian Goodyer

Ian  Goodyer

University position

Professor

Professor Ian Goodyer is pleased to consider applications from prospective PhD students.

Departments

Department of Psychiatry

Institutes

Developmental Psychiatry

Email

ig104@cam.ac.uk

Home page

http://www.psychiatry.cam.ac.uk/dev/Pro...

Research Themes

Developmental Neuroscience

Cognitive and Behavioural Neuroscience

Interests

I am a Child and Adolescent Psychiatrist based at Cambridge University pursuing research into the connections between human development and psychopathology. My studies are centred on adolescents in the community as well as current patients. Our research programme uses experimental and neuroimaging approaches embedded in longitudinal designs to measure the effects of genes and the social environment, on cognition and brain structures. We use these methods in epidemiological cohort studies of adolescent development and randomised controlled trials of treatment for depression and conduct disorders.

Research Focus

Keywords

depression

conduct

cognition

cortisol

adolescence

Clinical conditions

Conduct disorders

Depressive disorders

Equipment

Behavioural analysis

Cross-sectional and cohort studies

Hormone assays

Magnetic resonance imaging (MRI)

Randomised control trials

Collaborators

Cambridge

Ed Bullmore

Paul Fletcher

Joe Herbert

Peter Jones

Barbara Sahakian

United Kingdom

Ray Dolan

Peter Fonagy

Key publications

Owens M, Goodyer IM, Wilkinson P, Bhardwaj A, Abbott R, Croudace T, Dunn V, Jones PB, Walsh ND, Ban M, Sahakian BJ (2012), “5-HTTLPR and early childhood adversities moderate cognitive and emotional processing in adolescence.” PLoS One 7(11):e48482 Details

Walsh ND, Dalgleish T, Dunn VJ, Abbott R, St Clair MC, Owens M, Fairchild G, Kerslake WS, Hiscox LV, Passamonti L, Ewbank M, Ban M, Calder AJ, Goodyer IM (2012), “5-HTTLPR-environment interplay and its effects on neural reactivity in adolescents.” Neuroimage 63(3):1670-80 PDF Details

Fairchild G, Passamonti L, Hurford G, Hagan CC, von dem Hagen EA, van Goozen SH, Goodyer IM, Calder AJ (2011), “Brain structure abnormalities in early-onset and adolescent-onset conduct disorder.” Am J Psychiatry 168(6):624-33 Details

Goodyer IM, Croudace T, Dudbridge F, Ban M, Herbert J (2010), “Polymorphisms in BDNF (Val66Met) and 5-HTTLPR, morning cortisol and subsequent depression in at-risk adolescents.” Br J Psychiatry 197(5):365-71 Details

Passamonti L, Fairchild G, Goodyer IM, Hurford G, Hagan CC, Rowe JB, Calder AJ (2010), “Neural abnormalities in early-onset and adolescence-onset conduct disorder.” Arch Gen Psychiatry 67(7):729-38 Details

Goodyer I, Dubicka B, Wilkinson P, Kelvin R, Roberts C, Byford S, Breen S, Ford C, Barrett B, Leech A, Rothwell J, White L, Harrington R (2007), “Selective serotonin reuptake inhibitors (SSRIs) and routine specialist care with and without cognitive behaviour therapy in adolescents with major depression: randomised controlled trial.” BMJ 335(7611):142 Details

Publications

2014

Brodbeck J, Goodyer IM, Abbott RA, Dunn VJ, St Clair MC, Owens M, Jones PB, Croudace TJ (2014), “General distress, hopelessness-suicidal ideation and worrying in adolescence: concurrent and predictive validity of a symptom-level bifactor model for clinical diagnoses.” J Affect Disord 152-154:299-305 Details

Collings PJ, Wijndaele K, Corder K, Westgate K, Ridgway CL, Dunn V, Goodyer I, Ekelund U, Brage S (2014), “Levels and patterns of objectively-measured physical activity volume and intensity distribution in UK adolescents: the ROOTS study.” Int J Behav Nutr Phys Act 11:23 Details

Corder K, van Sluijs EM, Ridgway CL, Steele RM, Prynne CJ, Stephen AM, Bamber DJ, Dunn VJ, Goodyer IM, Ekelund U (2014), “Breakfast consumption and physical activity in adolescents: daily associations and hourly patterns.” Am J Clin Nutr 99(2):361-8 Details

Fairchild G, Hagan CC, Passamonti L, Walsh ND, Goodyer IM, Calder AJ (2014), “Atypical neural responses during face processing in female adolescents with conduct disorder.” J Am Acad Child Adolesc Psychiatry 53(6):677-687.e5 Details

Hay DF, Waters CS, Perra O, Swift N, Kairis V, Phillips R, Jones R, Goodyer I, Harold G, Thapar A, van Goozen S (2014), “Precursors to aggression are evident by 6 months of age.” Dev Sci 17(3):471-80 Details

Moutsiana C, Fearon P, Murray L, Cooper P, Goodyer I, Johnstone T, Halligan S (2014), “Making an effort to feel positive: insecure attachment in infancy predicts the neural underpinnings of emotion regulation in adulthood.” J Child Psychol Psychiatry Details

Owens M, Herbert J, Jones PB, Sahakian BJ, Wilkinson PO, Dunn VJ, Croudace TJ, Goodyer IM (2014), “Elevated morning cortisol is a stratified population-level biomarker for major depression in boys only with high depressive symptoms.” Proc Natl Acad Sci U S A 111(9):3638-43 Details

St Clair MC, Croudace T, Dunn VJ, Jones PB, Herbert J, Goodyer IM (2014), “Childhood adversity subtypes and depressive symptoms in early and late adolescence.” Dev Psychopathol :1-15 Details

2013

Fairchild G, van Goozen SH, Calder AJ, Goodyer IM (2013), “Research review: evaluating and reformulating the developmental taxonomic theory of antisocial behaviour.” J Child Psychol Psychiatry 54(9):924-40 Details

Fonagy P, Butler S, Goodyer I, Cottrell D, Scott S, Pilling S, Eisler I, Fuggle P, Kraam A, Byford S, Wason J, Haley R (2013), “Evaluation of multisystemic therapy pilot services in the Systemic Therapy for At Risk Teens (START) trial: study protocol for a randomised controlled trial.” Trials 14:265 Details

Graham J, Salimi-Khorshidi G, Hagan C, Walsh N, Goodyer I, Lennox B, Suckling J (2013), “Meta-analytic evidence for neuroimaging models of depression: state or trait?” J Affect Disord 151(2):423-31 Details

Hagan CC, Graham JM, Widmer B, Holt RJ, Ooi C, van Nieuwenhuizen AO, Fonagy P, Reynolds S, Target M, Kelvin R, Wilkinson PO, Bullmore ET, Lennox BR, Sahakian BJ, Goodyer I, Suckling J (2013), “Magnetic resonance imaging of a randomized controlled trial investigating predictors of recovery following psychological treatment in adolescents with moderate to severe unipolar depression: study protocol for Magnetic Resonance-Improving Mood with Psychoanalytic and Cognitive Therapies (MR-IMPACT).” BMC Psychiatry 13:247 Details

Ho V, Simmons RK, Ridgway CL, van Sluijs EM, Bamber DJ, Goodyer IM, Dunn VJ, Ekelund U, Corder K (2013), “Is wearing a pedometer associated with higher physical activity among adolescents?” Prev Med Details

Spence R, Owens M, Goodyer I (2013), “The longitudinal psychometric properties of the EAS temperament survey in adolescence.” J Pers Assess 95(6):633-9 Details

Waters CS, van Goozen S, Phillips R, Swift N, Hurst SL, Mundy L, Jones R, Jones I, Goodyer I, Hay DF (2013), “Infants at familial risk for depression show a distinct pattern of cortisol response to experimental challenge.” J Affect Disord 150(3):955-60 Details

Wilkinson PO, Croudace TJ, Goodyer IM (2013), “Rumination, anxiety, depressive symptoms and subsequent depression in adolescents at risk for psychopathology: a longitudinal cohort study.” BMC Psychiatry 13:250 Details

2012

Cole DA, Cho SJ, Martin NC, Youngstrom EA, March JS, Findling RL, Compas BE, Goodyer IM, Rohde P, Weissman M, Essex MJ, Hyde JS, Curry JF, Forehand R, Slattery MJ, Felton JW, Maxwell MA (2012), “Are increased weight and appetite useful indicators of depression in children and adolescents?” J Abnorm Psychol 121(4):838-51 Details

Fairchild G, Hagan CC, Walsh ND, Passamonti L, Calder AJ, Goodyer IM (2012), “Brain structure abnormalities in adolescent girls with conduct disorder.” J Child Psychol Psychiatry Details

Goodyer IM (2012), “Mathematical models as an aid for improving the validity of descriptive psychiatry.” Br J Psychiatry 201:335-6 Details

Hinrichs S, Owens M, Dunn V, Goodyer I (2012), “General practitioner experience and perception of Child and Adolescent Mental Health Services (CAMHS) care pathways: a multimethod research study.” BMJ Open 2(6) Details

Passamonti L, Fairchild G, Fornito A, Goodyer IM, Nimmo-Smith I, Hagan CC, Calder AJ (2012), “Abnormal Anatomical Connectivity between the Amygdala and Orbitofrontal Cortex in Conduct Disorder.” PLoS One 7(11):e48789 Details

Spence R, Owens M, Goodyer I (2012), “Item response theory and validity of the NEO-FFI in adolescents.” Pers Individ Dif 53(6-4):801-807 Details

Wilkinson PO, Harris C, Kelvin R, Dubicka B, Goodyer IM (2012), “Associations between adolescent depression and parental mental health, before and after treatment of adolescent depression.” Eur Child Adolesc Psychiatry Details

2011

Brodbeck J, Abbott RA, Goodyer IM, Croudace TJ (2011), “General and specific components of depression and anxiety in an adolescent population.” BMC Psychiatry 11:191 Details

Cole DA, Cai L, Martin NC, Findling RL, Youngstrom EA, Garber J, Curry JF, Hyde JS, Essex MJ, Compas BE, Goodyer IM, Rohde P, Stark KD, Slattery MJ, Forehand R (2011), “Structure and measurement of depression in youths: Applying item response theory to clinical data.” Psychol Assess Details

Dunn VJ, Abbott RA, Croudace TJ, Wilkinson P, Jones PB, Herbert J, Goodyer IM (2011), “Profiles of family-focused adverse experiences through childhood and early adolescence: the ROOTS project a community investigation of adolescent mental health.” BMC Psychiatry 11:109 Details

Goodyer IM, Tsancheva S, Byford S, Dubicka B, Hill J, Kelvin R, Reynolds S, Roberts C, Senior R, Suckling J, Wilkinson P, Target M, Fonagy P (2011), “Improving mood with psychoanalytic and cognitive therapies (IMPACT): a pragmatic effectiveness superiority trial to investigate whether specialised psychological treatment reduces the risk for relapse in adolescents with moderate to severe unipolar depression: study protocol for a randomised controlled trial.” Trials 12:175 Details

Ha C, Sharp C, Goodyer I (2011), “The role of child and parental mentalizing for the development of conduct problems over time.” Eur Child Adolesc Psychiatry 20(6):291-300 Details

Hay DF, Mundy L, Roberts S, Carta R, Waters CS, Perra O, Jones R, Jones I, Goodyer I, Harold G, Thapar A, van Goozen S (2011), “Known risk factors for violence predict 12-month-old infants' aggressiveness with peers.” Psychol Sci 22(9):1205-11 Details

Murray L, Arteche A, Fearon P, Halligan S, Goodyer I, Cooper P (2011), “Maternal postnatal depression and the development of depression in offspring up to 16 years of age.” J Am Acad Child Adolesc Psychiatry 50(5):460-70 Details

Prynne CJ, Handford C, Dunn V, Bamber D, Goodyer IM, Stephen AM (2011), “The quality of midday meals eaten at school by adolescents; school lunches compared with packed lunches and their contribution to total energy and nutrient intakes.” Public Health Nutr :1-8 Details

Ridgway CL, Brage S, Sharp SJ, Corder K, Westgate KL, van Sluijs EM, Goodyer IM, Hallal PC, Anderssen SA, Sardinha LB, Andersen LB, Ekelund U (2011), “Does birth weight influence physical activity in youth? A combined analysis of four studies using objectively measured physical activity.” PLoS One 6(1):e16125 Details

Russ SJ, Herbert J, Cooper P, Gunnar MR, Goodyer I, Croudace T, Murray L (2011), “Cortisol levels in response to starting school in children at increased risk for social phobia.” Psychoneuroendocrinology Details

St Clair MC, Goodyer IM, Dunn V, Herbert J, Jones PB, Croudace T (2011), “Depressive symptoms during adolescence: comparison between epidemiological and high risk sampling.” Soc Psychiatry Psychiatr Epidemiol Details

Wilkinson P, Goodyer I (2011), “Non-suicidal self-injury.” Eur Child Adolesc Psychiatry Details

Wilkinson P, Kelvin R, Roberts C, Dubicka B, Goodyer I (2011), “Clinical and Psychosocial Predictors of Suicide Attempts and Nonsuicidal Self-Injury in the Adolescent Depression Antidepressants and Psychotherapy Trial (ADAPT).” Am J Psychiatry Details

Wilkinson PO, Goodyer IM (2011), “Childhood adversity and allostatic overload of the hypothalamic-pituitary-adrenal axis: A vulnerability model for depressive disorders.” Dev Psychopathol 23(4):1017-37 Details

2010

Akister J, Owens M, Goodyer IM (2010), “Leaving care and mental health: outcomes for children in out-of-home care during the transition to adulthood.” Health Res Policy Syst 8:10 Details

Corder K, van Sluijs EM, Steele RM, Stephen AM, Dunn V, Bamber D, Goodyer I, Griffin SJ, Ekelund U (2010), “Breakfast consumption and physical activity in British adolescents.” Br J Nutr :1-6 Details

Dubicka B, Elvins R, Roberts C, Chick G, Wilkinson P, Goodyer IM (2010), “Combined treatment with cognitive-behavioural therapy in adolescent depression: meta-analysis.” Br J Psychiatry 197:433-40 Details

Fairchild G, Stobbe Y, van Goozen SH, Calder AJ, Goodyer IM (2010), “Facial expression recognition, fear conditioning, and startle modulation in female subjects with conduct disorder.” Biol Psychiatry 68(3):272-9 Details

Goodyer IM, Wilkinson P, Dubicka B, Kelvin R (2010), “Forum: the use of selective serotonin reuptake inhibitors in depressed children and adolescents: commentary on the meta-analysis by Hetrick et al.” Curr Opin Psychiatry 23(1):58-61 Details

Hay DF, Perra O, Hudson K, Waters CS, Mundy L, Phillips R, Goodyer I, Harold G, Thapar A, van Goozen S, the CCDS Team (2010), “Identifying early signs of aggression: psychometric properties of the cardiff infant contentiousness scale.” Aggress Behav Details

2009

Fairchild G, Van Goozen SH, Calder AJ, Stollery SJ, Goodyer IM (2009), “Deficits in facial expression recognition in male adolescents with early-onset or adolescence-onset conduct disorder.” J Child Psychol Psychiatry 50(5):627-36 Details

Fairchild G, van Goozen SH, Stollery SJ, Aitken MR, Savage J, Moore SC, Goodyer IM (2009), “Decision making and executive function in male adolescents with early-onset or adolescence-onset conduct disorder and control subjects.” Biol Psychiatry 66(2):162-8 Details

Goodyer IM, Bacon A, Ban M, Croudace T, Herbert J (2009), “Serotonin transporter genotype, morning cortisol and subsequent depression in adolescents.” Br J Psychiatry 195(1):39-45 Details

Goodyer IM, Croudace T, Dunn V, Herbert J, Jones PB (2009), “Cohort Profile: Risk patterns and processes for psychopathology emerging during adolescence: the ROOTS project.” Int J Epidemiol Details

Murray L, Halligan SL, Goodyer I, Herbert J (2009), “Disturbances in early parenting of depressed mothers and cortisol secretion in offspring: A preliminary study.” J Affect Disord Details

Newbury DF, Winchester L, Addis L, Paracchini S, Buckingham LL, Clark A, Cohen W, Cowie H, Dworzynski K, Everitt A, Goodyer IM, Hennessy E, Kindley AD, Miller LL, Nasir J, O'Hare A, Shaw D, Simkin Z, Simonoff E, Slonims V, Watson J, Ragoussis J, Fisher SE, Seckl JR, Helms PJ, Bolton PF, Pickles A, Conti-Ramsden G, Baird G, Bishop DV, Monaco AP (2009), “CMIP and ATP2C2 modulate phonological short-term memory in language impairment.” Am J Hum Genet 85(2):264-72 Details

Wilkinson P, Dubicka B, Kelvin R, Roberts C, Goodyer I (2009), “Treated depression in adolescents: predictors of outcome at 28 weeks.” Br J Psychiatry 194(4):334-41 Details

2008

Fairchild G, van Goozen SH, Stollery SJ, Brown J, Gardiner J, Herbert J, Goodyer IM (2008), “Cortisol diurnal rhythm and stress reactivity in male adolescents with early-onset or adolescence-onset conduct disorder.” Biol Psychiatry 64(7):599-606 Details

Fairchild G, Van Goozen SH, Stollery SJ, Goodyer IM (2008), “Fear conditioning and affective modulation of the startle reflex in male adolescents with early-onset or adolescence-onset conduct disorder and healthy control subjects.” Biol Psychiatry 63(3):279-85 Details

Falcaro M, Pickles A, Newbury DF, Addis L, Banfield E, Fisher SE, Monaco AP, Simkin Z, Conti-Ramsden G, SLI Consortium (2008), “Genetic and phenotypic effects of phonological short-term memory and grammatical morphology in specific language impairment.” Genes Brain Behav 7(4):393-402 Details

Goodyer IM (2008), “Emanuel Miller Lecture: early onset depressions--meanings, mechanisms and processes.” J Child Psychol Psychiatry 49(12):1239-56 Details

Goodyer IM, Dubicka B, Wilkinson P, Kelvin R, Roberts C, Byford S, Breen S, Ford C, Barrett B, Leech A, Rothwell J, White L, Harrington R (2008), “A randomised controlled trial of cognitive behaviour therapy in adolescents with major depression treated by selective serotonin reuptake inhibitors. The ADAPT trial.” Health Technol Assess 12(14):iii-iv, ix-60 Details

Sharp C, Petersen N, Goodyer I (2008), “Emotional reactivity and the emergence of conduct problems and emotional symptoms in 7- to 11-year-olds: a 1-year follow-up study.” J Am Acad Child Adolesc Psychiatry 47(5):565-73 Details

Wilkinson PO, Goodyer IM (2008), “The effects of cognitive-behavioural therapy on mood-related ruminative response style in depressed adolescents.” Child Adolesc Psychiatry Ment Health 2(1):3 Details

2007

Byford S, Barrett B, Roberts C, Wilkinson P, Dubicka B, Kelvin RG, White L, Ford C, Breen S, Goodyer I (2007), “Cost-effectiveness of selective serotonin reuptake inhibitors and routine specialist care with and without cognitive behavioural therapy in adolescents with major depression.” Br J Psychiatry 191:521-7 Details

Duffy A, Alda M, Trinneer A, Demidenko N, Grof P, Goodyer IM (2007), “Temperament, life events, and psychopathology among the offspring of bipolar parents.” Eur Child Adolesc Psychiatry 16(4):222-8 Details

Halligan SL, Herbert J, Goodyer I, Murray L (2007), “Disturbances in morning cortisol secretion in association with maternal postnatal depression predict subsequent depressive symptomatology in adolescents.” Biol Psychiatry 62(1):40-6 Details

2006

Dunn V, Goodyer IM (2006), “Longitudinal investigation into childhood- and adolescence-onset depression: psychiatric outcome in early adulthood.” Br J Psychiatry 188:216-22 Details

Herbert J, Goodyer IM, Grossman AB, Hastings MH, de Kloet ER, Lightman SL, Lupien SJ, Roozendaal B, Seckl JR (2006), “Do corticosteroids damage the brain?” J Neuroendocrinol 18(6):393-411 Details

Kyte ZA, Carlson GA, Goodyer IM (2006), “Clinical and neuropsychological characteristics of child and adolescent bipolar disorder.” Psychol Med 36(9):1197-211 Details

Murray L, Halligan SL, Adams G, Patterson P, Goodyer IM (2006), “Socioemotional development in adolescents at risk for depression: the role of maternal depression and attachment style.” Dev Psychopathol 18(2):489-516 Details

Sharp C, Goodyer IM, Croudace TJ (2006), “The Short Mood and Feelings Questionnaire (SMFQ): a unidimensional item response theory and categorical data factor analysis of self-report ratings from a community sample of 7-through 11-year-old children.” J Abnorm Child Psychol 34(3):379-91 Details

Wilkinson PO, Goodyer IM (2006), “Attention difficulties and mood-related ruminative response style in adolescents with unipolar depression.” J Child Psychol Psychiatry 47(12):1284-91 Details