Dr Helene Gautier
I showed that communication between axons and oligodendrocyte progenitor cells during remyelination is essential for efficient myelin repair.
I'm now interested on how neurons sense their mechanical environment and if it influences their electrical properties.
Electrophysiological recording techniques
Field potential recording
Whole cell patch clamp
Associated News Items
Lundgaard I, Luzhynskaya A, Stockley JH, Wang Z, Evans KA, Swire M, Volbracht K, Gautier HO, Franklin RJ, Charles Ffrench-Constant, Attwell D, Káradóttir RT (2013), “Neuregulin and BDNF induce a switch to NMDA receptor-dependent myelination by oligodendrocytes.” PLoS Biol 11(12):e1001743 Details
Christ AF, Franze K, Gautier H, Moshayedi P, Fawcett J, Franklin RJ, Karadottir RT, Guck J (2010), “Mechanical difference between white and gray matter in the rat cerebellum measured by scanning force microscopy.” J Biomech Details
Meme S, Calas AG, Montécot C, Richard O, Gautier H, Gefflaut T, Doan BT, Même W, Pichon J, Beloeil JC (2009), “MRI characterization of structural mouse brain changes in response to chronic exposure to the glufosinate ammonium herbicide.” Toxicol Sci 111(2):321-30 Details
Gautier H, Auger J, Legros C, Lapied B (2008), “Calcium-activated potassium channels in insect pacemaker neurons as unexpected target site for the novel fumigant dimethyl disulfide.” J Pharmacol Exp Ther 324(1):149-59 Details
Wicher D, Derst C, Gautier H, Lapied B, Heinemann SH, Agricola HJ (2007), “The satiety signaling neuropeptide perisulfakinin inhibits the activity of central neurons promoting general activity.” Front Cell Neurosci 1:3 Details
Lavialle-Defaix C, Gautier H, Defaix A, Lapied B, Grolleau F (2006), “Differential regulation of two distinct voltage-dependent sodium currents by group III metabotropic glutamate receptor activation in insect pacemaker neurons.” J Neurophysiol 96(5):2437-50 Details