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    Professor Ed Bullmore

    University Position
    Professor

    Interests

    I am interested in understanding human brain network organization from neuroimaging data in health and disease. My recent methodological work has focused on graph theory to measure aspects of brain network topology. I am also interested in better neuroscientific understanding and treatment of psychiatric disorders. I am currently leading a consortium funded by the Wellcome Trust and pharmaceutical companies (GSK, Janssen, Lundbeck) - the Neuroimmunology of Mood Disorders and Alzheimer's Disease (NIMA) consortium - which is exploring immune mechanisms and therapeutics for depression and dementia.

    Key Publications

    Sexually divergent development of depression-related brain networks during healthy human adolescence.

    DOI: http://doi.org/10.1126/sciadv.abm7825
    Journal: Sci Adv
    E-pub date: 27 May 2022
    Authors: L Dorfschmidt, RA Bethlehem, J Seidlitz, F Váša, SR White, R Romero-García, MG Kitzbichler, AR Aruldass, SE Morgan, IM Goodyer, P Fonagy, PB Jones, RJ Dolan, NSPN Consortium, NA Harrison, PE Vértes, ET Bullmore

    Impaired Learning From Negative Feedback in Stimulant Use Disorder: Dopaminergic Modulation.

    DOI: http://doi.org/10.1093/ijnp/pyab041
    Journal: Int J Neuropsychopharmacol
    E-pub date: 12 Nov 2021
    Authors: TV Lim, RN Cardinal, ET Bullmore, TW Robbins, KD Ersche

    B-cells are abnormal in psychosocial stress and regulate meningeal myeloid cell activation.

    DOI: http://doi.org/10.1016/j.bbi.2021.08.002
    Journal: Brain Behav Immun
    E-pub date: 1 Oct 2021
    Authors: M-E Lynall, SL Kigar, ML Lehmann, AE DePuyt, ZK Tuong, SJ Listwak, AG Elkahloun, ET Bullmore, M Herkenham, MR Clatworthy

    Brain charts for the human lifespan

    DOI: http://doi.org/10.1101/2021.06.08.447489
    Journal:
    E-pub date: 1 Aug 2021
    Authors: RAI Bethlehem, J Seidlitz, SR White, JW Vogel, KM Anderson, C Adamson, S Adler, GS Alexopoulos, E Anagnostou, A Areces-Gonzalez, DE Astle, B Auyeung, M Ayub, G Ball, S Baron-Cohen, R Beare, SA Bedford, V Benegal, F Beyer, J Bin Bae, J Blangero, M Blesa Cábez, JP Boardman, M Borzage, JF Bosch-Bayard, N Bourke, VD Calhoun, MM Chakravarty, C Chen, C Chertavian, G Chetelat, YS Chong, JH Cole, A Corvin, M Costantino, E Courchesne, F Crivello, VL Cropley, J Crosbie, N Crossley, M Delarue, R Delorme, S Desrivieres, G Devenyi, MA Di Biase, R Dolan, KA Donald, G Donohoe, K Dunlop, AD Edwards, JT Elison, CT Ellis, JA Elman, L Eyler, DA Fair, E Feczko, PC Fletcher, P Fonagy, CE Franz, L Galan-Garcia, A Gholipour, J Giedd, JH Gilmore, DC Glahn, I Goodyer, PE Grant, NA Groenewold, FM Gunning, RE Gur, RC Gur, CF Hammill, O Hansson, T Hedden, A Heinz, RN Henson, K Heuer, J Hoare, B Holla, AJ Holmes, R Holt, H Huang, K Im, J Ipser, CR Jack, AP Jackowski, T Jia, KA Johnson, PB Jones, DT Jones, R Kahn, H Karlsson, L Karlsson, R Kawashima, EA Kelley, S Kern, K Kim, MG Kitzbichler, WS Kremen, F Lalonde, B Landeau, S Lee, J Lerch, JD Lewis, J Li, W Liao, C Liston, MV Lombardo, J Lv, C Lynch, TT Mallard, M Marcelis, RD Markello, SR Mathias, B Mazoyer, P McGuire, MJ Meaney, A Mechelli, N Medic, B Misic, SE Morgan, D Mothersill, J Nigg, MQW Ong, C Ortinau, C Ortinau, R Ossenkoppele, M Ouyang, L Palaniyappan, L Paly, PM Pan, C Pantelis, MM Park, T Paus, Z Pausova, D Paz-Linares, A Pichet Binette, K Pierce, X Qian, J Qiu, A Qiu, A Raznahan, T Rittman, A Rodrigue, CK Rollins, R Romero-Garcia, L Ronan, MD Rosenberg, DH Rowitch, GA Salum, TD Satterthwaite, HL Schaare, RJ Schachar, AP Schultz, G Schumann, M Schöll, D Sharp, RT Shinohara, I Skoog, CD Smyser, RA Sperling, DJ Stein, A Stolicyn, J Suckling, G Sullivan, Y Taki, B Thyreau, R Toro, N Traut, KA Tsvetanov, NB Turk-Browne, JJ Tuulari, C Tzourio, É Vachon-Presseau, MJ Valdes-Sosa, PA Valdes-Sosa, SL Valk, T van Amelsvoort, SN Vandekar, L Vasung, LW Victoria, S Villeneuve, A Villringer, A Villringer, PE Vértes, K Wagstyl, YS Wang, SK Warfield, V Warrier, E Westman, ML Westwater, HC Whalley, AV Witte, N Yang, B Yeo, H Yun, A Zalesky, HJ Zar, A Zettergren, JH Zhou, H Ziauddeen, A Zugman, XN Zuo, ET Bullmore, AF Alexander-Bloch, 3R-BRAIN, AIBL, Alzheimer’s Disease Neuroimaging Initiative, Alzheimer’s Disease Repository Without Borders Investigators, UMN BCP, CALM Team, Cam-CAN, CCNP, COBRE, Developing Human Connectome Project, ENIGMA Developmental Brain Age working group, FinnBrain, Harvard Aging Brain Study, IMAGEN, KNE96, The Mayo Clinic Study of Aging, NSPN, POND, The PREVENT-AD Research Group, VETSA

    A generative network model of neurodevelopmental diversity in structural brain organization.

    DOI: http://doi.org/10.1038/s41467-021-24430-z
    Journal: Nat Commun
    E-pub date: 9 Jul 2021
    Authors: D Akarca, PE Vértes, ET Bullmore, CALM team, DE Astle

    Peripheral Blood Cell-Stratified Subgroups of Inflamed Depression.

    DOI: http://doi.org/10.1016/j.biopsych.2019.11.017
    Journal: Biol Psychiatry
    E-pub date: 15 Jul 2020
    Authors: M-E Lynall, L Turner, J Bhatti, J Cavanagh, P de Boer, V Mondelli, D Jones, WC Drevets, P Cowen, NA Harrison, CM Pariante, L Pointon, MR Clatworthy, E Bullmore, Neuroimmunology of Mood Disorders and Alzheimer’s Disease (NIMA) Consortium

    Conservative and disruptive modes of adolescent change in human brain functional connectivity.

    DOI: http://doi.org/10.1073/pnas.1906144117
    Journal: Proc Natl Acad Sci U S A
    E-pub date: 11 Feb 2020
    Authors: F Váša, R Romero-Garcia, MG Kitzbichler, J Seidlitz, KJ Whitaker, MM Vaghi, P Kundu, AX Patel, P Fonagy, RJ Dolan, PB Jones, IM Goodyer, NSPN Consortium, PE Vértes, ET Bullmore

    Birth weight, family history of diabetes and diabetes onset in schizophrenia.

    DOI: http://doi.org/10.1136/bmjdrc-2019-001036
    Journal: BMJ Open Diabetes Res Care
    E-pub date: 1 Jan 2020
    Authors: E Fernandez-Egea, R Walker, H Ziauddeen, RN Cardinal, ET Bullmore

    Synaptic and transcriptionally downregulated genes are associated with cortical thickness differences in autism.

    DOI: http://doi.org/10.1038/s41380-018-0023-7
    Journal: Mol Psychiatry
    E-pub date: 1 Jul 2019
    Authors: R Romero-Garcia, V Warrier, ET Bullmore, S Baron-Cohen, RAI Bethlehem

    Cortical patterning of abnormal morphometric similarity in psychosis is associated with brain expression of schizophrenia-related genes.

    DOI: http://doi.org/10.1073/pnas.1820754116
    Journal: Proc Natl Acad Sci U S A
    E-pub date: 7 May 2019
    Authors: SE Morgan, J Seidlitz, KJ Whitaker, R Romero-Garcia, NE Clifton, C Scarpazza, T van Amelsvoort, M Marcelis, J van Os, G Donohoe, D Mothersill, A Corvin, A Pocklington, A Raznahan, P McGuire, PE Vértes, ET Bullmore

    Using fMRI connectivity to define a treatment-resistant form of post-traumatic stress disorder.

    DOI: http://doi.org/10.1126/scitranslmed.aal3236
    Journal: Sci Transl Med
    E-pub date: 3 Apr 2019
    Authors: A Etkin, A Maron-Katz, W Wu, GA Fonzo, J Huemer, PE Vértes, B Patenaude, J Richiardi, MS Goodkind, CJ Keller, J Ramos-Cejudo, YV Zaiko, KK Peng, E Shpigel, P Longwell, RT Toll, A Thompson, S Zack, B Gonzalez, R Edelstein, J Chen, I Akingbade, E Weiss, R Hart, S Mann, K Durkin, SH Baete, FE Boada, A Genfi, J Autea, J Newman, DJ Oathes, SE Lindley, D Abu-Amara, BA Arnow, N Crossley, J Hallmayer, S Fossati, BO Rothbaum, CR Marmar, ET Bullmore, R O'Hara

    Replicable and Coupled Changes in Innate and Adaptive Immune Gene Expression in Two Case-Control Studies of Blood Microarrays in Major Depressive Disorder.

    DOI: http://doi.org/10.1016/j.biopsych.2017.01.021
    Journal: Biol Psychiatry
    E-pub date: 1 Jan 2018
    Authors: GGR Leday, PE Vértes, S Richardson, JR Greene, T Regan, S Khan, R Henderson, TC Freeman, CM Pariante, NA Harrison, MRC Immunopsychiatry Consortium, VH Perry, WC Drevets, GM Wittenberg, ET Bullmore

    The Multilayer Connectome of Caenorhabditis elegans.

    DOI: http://doi.org/10.1371/journal.pcbi.1005283
    Journal: PLoS Comput Biol
    E-pub date: 1 Dec 2016
    Authors: B Bentley, R Branicky, CL Barnes, YL Chew, E Yemini, ET Bullmore, PE Vértes, WR Schafer

    Phase transition in the economically modeled growth of a cellular nervous system.

    DOI: http://doi.org/10.1073/pnas.1300753110
    Journal: Proc Natl Acad Sci U S A
    E-pub date: 7 May 2013
    Authors: V Nicosia, PE Vértes, WR Schafer, V Latora, ET Bullmore

    The rich club of the C. elegans neuronal connectome.

    DOI: http://doi.org/10.1523/JNEUROSCI.3784-12.2013
    Journal: J Neurosci
    E-pub date: 10 Apr 2013
    Authors: EK Towlson, PE Vértes, SE Ahnert, WR Schafer, ET Bullmore

    Simple models of human brain functional networks.

    DOI: http://doi.org/10.1073/pnas.1111738109
    Journal: Proc Natl Acad Sci U S A
    E-pub date: 10 Apr 2012
    Authors: PE Vértes, AF Alexander-Bloch, N Gogtay, JN Giedd, JL Rapoport, ET Bullmore

    Fetal testosterone influences sexually dimorphic gray matter in the human brain.

    DOI: http://doi.org/10.1523/JNEUROSCI.4389-11.2012
    Journal: J Neurosci
    E-pub date: 11 Jan 2012
    Authors: MV Lombardo, E Ashwin, B Auyeung, B Chakrabarti, K Taylor, G Hackett, ET Bullmore, S Baron-Cohen

    Functional magnetic resonance imaging of synesthesia: activation of V4/V8 by spoken words.

    DOI: http://doi.org/10.1038/nn818
    Journal: Nat Neurosci
    E-pub date: 1 Apr 2002
    Authors: JA Nunn, LJ Gregory, M Brammer, SCR Williams, DM Parslow, MJ Morgan, RG Morris, ET Bullmore, S Baron-Cohen, JA Gray

    Social intelligence in the normal and autistic brain: an fMRI study.

    DOI: http://doi.org/10.1046/j.1460-9568.1999.00621.x
    Journal: Eur J Neurosci
    E-pub date: 1 Jun 1999
    Authors: S Baron-Cohen, HA Ring, S Wheelwright, ET Bullmore, MJ Brammer, A Simmons, SC Williams

    Publications

    Characterizing Subcortical Structural Heterogeneity in Autism.

    DOI: http://doi.org/10.1101/2023.08.28.554882
    Journal:
    E-pub date: 29 Aug 2023
    Authors: DN MacDonald, SA Bedford, E Olafson, MTM Park, GA Devenyi, S Tullo, R Patel, E Anagnostou, S Baron-Cohen, ET Bullmore, LR Chura, MC Craig, C Ecker, DL Floris, RJ Holt, R Lenroot, JP Lerch, MV Lombardo, DGM Murphy, A Raznahan, ANV Ruigrok, E Smith, RT Shinohara, MD Spencer, J Suckling, MJ Taylor, A Thurm, MRC AIMS Consortium, M-C Lai, MM Chakravarty

    Prefrontal Cortex Activation and Stopping Performance Underlie the Beneficial Effects of Atomoxetine on Response Inhibition in Healthy Volunteers and Those With Cocaine Use Disorder.

    DOI: http://doi.org/10.1016/j.bpsc.2021.08.010
    Journal: Biol Psychiatry Cogn Neurosci Neuroimaging
    E-pub date: 1 Nov 2022
    Authors: P Zhukovsky, S Morein-Zamir, H Ziauddeen, E Fernandez-Egea, C Meng, R Regenthal, BJ Sahakian, ET Bullmore, TW Robbins, JW Dalley, KD Ersche

    Hospitalisation for COVID-19 predicts long lasting cerebrovascular impairment: A prospective observational cohort study

    DOI: http://doi.org/10.1101/2022.02.01.22270235
    Journal:
    E-pub date: 1 Aug 2022
    Authors: K Tsvetanov, L Spindler, E Stamatakis, VFJ Newcombe, V Lupson, D Chatfield, A Manktelow, J Outtrim, A Elmer, N Kingston, J Bradley, E Bullmore, J Rowe, D Menon, The Cambridge NeuroCOVID Group, The NIHR COVID-19 BioResource, The Cambridge NIHR Clinical Research Facility, The CITIID-NIHR BioResource COVID-19 Collaboration

    Brain charts for the human lifespan

    DOI: http://doi.org/10.1038/s41586-022-04554-y
    Journal: Nature
    E-pub date: 6 Apr 2022
    Authors: RAI Bethlehem, J Seidlitz, SR White, JW Vogel, KM Anderson, C Adamson, S Adler, GS Alexopoulos, E Anagnostou, A Areces-Gonzalez, DE Astle, B Auyeung, M Ayub, G Ball, S Baron-Cohen, R Beare, SA Bedford, V Benegal, F Beyer, J Bin Bae, J Blangero, M Blesa Cábez, JP Boardman, M Borzage, JF Bosch-Bayard, N Bourke, VD Calhoun, MM Chakravarty, C Chen, C Chertavian, G Chetelat, YS Chong, JH Cole, A Corvin, E Courchesne, F Crivello, VL Cropley, J Crosbie, N Crossley, M Delarue, S Desrivieres, G Devenyi, MA Di Biase, R Dolan, KA Donald, G Donohoe, K Dunlop, AD Edwards, JT Elison, CT Ellis, JA Elman, L Eyler, DA Fair, PC Fletcher, P Fonagy, CE Franz, L Galan-Garcia, A Gholipour, J Giedd, JH Gilmore, DC Glahn, I Goodyer, PE Grant, NA Groenewold, FM Gunning, RE Gur, RC Gur, CF Hammill, O Hansson, T Hedden, A Heinz, R Henson, K Heuer, J Hoare, B Holla, AJ Holmes, R Holt, H Huang, K Im, J Ipser, CR Jack, AP Jackowski, T Jia, KA Johnson, PB Jones, DT Jones, R Kahn, H Karlsson, L Karlsson, R Kawashima, EA Kelley, S Kern, K Kim, MG Kitzbichler, WS Kremen, F Lalonde, B Landeau, S Lee, J Lerch, JD Lewis, J Li, W Liao, DP Linares, C Liston, MV Lombardo, J Lv, C Lynch, TT Mallard, M Marcelis, RD Markello, B Mazoyer, P McGuire, MJ Meaney, A Mechelli, N Medic, B Misic, SE Morgan, D Mothersill, J Nigg, MQW Ong, C Ortinau, R Ossenkoppele, M Ouyang, L Palaniyappan, L Paly, PM Pan, C Pantelis, MM Park, T Paus, Z Pausova, A Pichet Binette, K Pierce, X Qian, J Qiu, A Qiu, A Raznahan, T Rittman, CK Rollins, R Romero-Garcia, L Ronan, MD Rosenberg, DH Rowitch, GA Salum, TD Satterthwaite, HL Schaare, RJ Schachar, AP Schultz, G Schumann, M Schöll, D Sharp, RT Shinohara, I Skoog, CD Smyser, RA Sperling, DJ Stein, A Stolicyn, J Suckling, G Sullivan, Y Taki, B Thyreau, R Toro, KA Tsvetanov, NB Turk-Browne, JJ Tuulari, C Tzourio, É Vachon-Presseau, MJ Valdes-Sosa, PA Valdes-Sosa, SL Valk, T van Amelsvoort, SN Vandekar, L Vasung, LW Victoria, S Villeneuve, A Villringer, PE Vértes, K Wagstyl, YS Wang, SK Warfield, V Warrier, E Westman, ML Westwater, HC Whalley, AV Witte, N Yang, BTT Yeo, HJ Yun, A Zalesky, HJ Zar, A Zettergren, JH Zhou, H Ziauddeen, A Zugman, XN Zuo, AF Alexander-Bloch, AIBL, Alzheimer’s Disease Neuroimaging Initiative, Alzheimer’s Disease Repository Without Borders Investigators, ASRB, CALM Team, Cam-CAN, CCNP, 3R-BRAIN, COBRE, ENIGMA Developmental Brain Age working group, FinnBrain, Harvard Aging Brain Study, IMAGEN, KNE96, NSPN, OASIS-3, OpenPain Project, POND, The PREVENT-AD Research Group, VETSA, Bullmore, E.T

    Methylome-wide association study of antidepressant use in Generation Scotland and the Netherlands Twin Register implicates the innate immune system.

    DOI: http://doi.org/10.1038/s41380-021-01412-7
    Journal: Mol Psychiatry
    E-pub date: 1 Mar 2022
    Authors: MC Barbu, F Huider, A Campbell, C Amador, MJ Adams, M-E Lynall, DM Howard, RM Walker, SW Morris, J Van Dongen, DJ Porteous, KL Evans, E Bullmore, G Willemsen, DI Boomsma, HC Whalley, AM McIntosh

    Dysconnectivity of a brain functional network was associated with blood inflammatory markers in depression.

    DOI: http://doi.org/10.1016/j.bbi.2021.08.226
    Journal: Brain Behav Immun
    E-pub date: 1 Nov 2021
    Authors: AR Aruldass, MG Kitzbichler, SE Morgan, S Lim, M-E Lynall, L Turner, P Vertes, Wellcome Trust Consortium for Neuroimmunology of Mood Disorders and Alzheimer’s Disease (NIMA), J Cavanagh, P Cowen, CM Pariante, NA Harrison, ET Bullmore

    Challenges and opportunities for conducting a vaccine trial during the COVID-19 pandemic in the United Kingdom.

    DOI: http://doi.org/10.1177/17407745211024764
    Journal: Clin Trials
    E-pub date: 1 Oct 2021
    Authors: ME Török, BR Underwood, M Toshner, C Waddington, E Sidhom, K Sharrocks, R Bousfield, C Summers, C Saunders, Z McIntyre, H Morris, J Piper, G Calderon, S Dennis, T Assari, AM de Rotrou, A Shaw, J Bradley, J O'Brien, RC Rintoul, I Smith, E Bullmore, K Chatterjee, Cambridge COVID Vaccine Trial Team

    Grey and white matter micro-structure is associated with polygenic risk for schizophrenia

    DOI: http://doi.org/10.1101/2021.02.06.21251073
    Journal:
    E-pub date: 1 Aug 2021
    Authors: E-M Stauffer, RAI Bethlehem, V Warrier, G Murray, R Romero-Garcia, J Seidlitz, E Bullmore

    No evidence for differential gene expression in major depressive disorder PBMCs, but robust evidence of elevated biological ageing.

    DOI: http://doi.org/10.1038/s41398-021-01506-4
    Journal: Transl Psychiatry
    E-pub date: 22 Jul 2021
    Authors: JJ Cole, A McColl, R Shaw, M-E Lynall, PJ Cowen, P de Boer, WC Drevets, N Harrison, C Pariante, L Pointon, NIMA consortium, C Goodyear, E Bullmore, J Cavanagh

    Bridging Brain and Cognition: A Multilayer Network Analysis of Brain Structural Covariance and General Intelligence in a Developmental Sample of Struggling Learners.

    DOI: http://doi.org/10.3390/jintelligence9020032
    Journal: J Intell
    E-pub date: 15 Jun 2021
    Authors: IL Simpson-Kent, EI Fried, D Akarca, S Mareva, ET Bullmore, The Calm Team, RA Kievit

    Examining the Boundary Sharpness Coefficient as an Index of Cortical Microstructure in Autism Spectrum Disorder.

    DOI: http://doi.org/10.1093/cercor/bhab015
    Journal: Cereb Cortex
    E-pub date: 10 Jun 2021
    Authors: E Olafson, SA Bedford, GA Devenyi, R Patel, S Tullo, MTM Park, O Parent, E Anagnostou, S Baron-Cohen, ET Bullmore, LR Chura, MC Craig, C Ecker, DL Floris, RJ Holt, R Lenroot, JP Lerch, MV Lombardo, DGM Murphy, A Raznahan, ANV Ruigrok, MD Spencer, J Suckling, MJ Taylor, MRC AIMS Consortium, M-C Lai, MM Chakravarty

    [11C]PK11195-PET Brain Imaging of the Mitochondrial Translocator Protein in Mitochondrial Disease.

    DOI: http://doi.org/10.1212/WNL.0000000000012033
    Journal: Neurology
    E-pub date: 31 May 2021
    Authors: J van den Ameele, Y Hong, R Manavaki, A Kouli, H Biggs, Z MacIntyre, R Horvath, P Yu-Wai-Man, E Reid, CH Williams-Gray, E Bullmore, F Aigbirhio, T Fryer, P Chinnery

    Examining volumetric gradients based on the frustum surface ratio in the brain in autism spectrum disorder.

    DOI: http://doi.org/10.1002/hbm.25270
    Journal: Hum Brain Mapp
    E-pub date: 1 Mar 2021
    Authors: C Mann, T Schäfer, A Bletsch, M Gudbrandsen, E Daly, J Suckling, ET Bullmore, MV Lombardo, M-C Lai, MC Craig, MRC AIMS Consortium, S Baron-Cohen, DGM Murphy, C Ecker

    Atypical measures of diffusion at the gray-white matter boundary in autism spectrum disorder in adulthood.

    DOI: http://doi.org/10.1002/hbm.25237
    Journal: Hum Brain Mapp
    E-pub date: 1 Feb 2021
    Authors: A Bletsch, T Schäfer, C Mann, DS Andrews, E Daly, M Gudbrandsen, ANV Ruigrok, R Dallyn, R Romero-Garcia, M-C Lai, MV Lombardo, MC Craig, J Suckling, ET Bullmore, S Baron-Cohen, MRC AIMS Consortium, DGM Murphy, F Dell'Acqua, C Ecker

    Neuroanatomical substrates of generalized brain dysfunction in COVID-19.

    DOI: http://doi.org/10.1007/s00134-020-06241-w
    Journal: Intensive Care Med
    E-pub date: 1 Jan 2021
    Authors: VFJ Newcombe, LRB Spindler, T Das, S Winzeck, K Allinson, EA Stamatakis, DK Menon, Cambridge NeuroCovid Imaging Collaborators

    The early impact of COVID-19 on mental health and community physical health services and their patients’ mortality in Cambridgeshire and Peterborough, UK.

    DOI: http://doi.org/10.1016/j.jpsychires.2020.09.020
    Journal: J Psychiatr Res
    E-pub date: 1 Dec 2020
    Authors: S Chen, PB Jones, BR Underwood, A Moore, ET Bullmore, S Banerjee, EF Osimo, JB Deakin, CF Hatfield, FJ Thompson, JD Artingstall, MP Slann, JR Lewis, RN Cardinal

    Sex-specific impact of prenatal androgens on social brain default mode subsystems.

    DOI: http://doi.org/10.1038/s41380-018-0198-y
    Journal: Mol Psychiatry
    E-pub date: 1 Sep 2020
    Authors: MV Lombardo, B Auyeung, T Pramparo, A Quartier, J Courraud, RJ Holt, J Waldman, ANV Ruigrok, N Mooney, RAI Bethlehem, M-C Lai, P Kundu, ET Bullmore, J-L Mandel, A Piton, S Baron-Cohen

    Reinforcement learning as an intermediate phenotype in psychosis? Deficits sensitive to illness stage but not associated with polygenic risk of schizophrenia in the general population.

    DOI: http://doi.org/10.1016/j.schres.2020.04.022
    Journal: Schizophr Res
    E-pub date: 31 Aug 2020
    Authors: M Montagnese, F Knolle, J Haarsma, JD Griffin, A Richards, PE Vertes, B Kiddle, PC Fletcher, PB Jones, MJ Owen, P Fonagy, ET Bullmore, RJ Dolan, NSPN Consortium, M Moutoussis, IM Goodyer, GK Murray

    Intrinsic excitation-inhibition imbalance affects medial prefrontal cortex differently in autistic men versus women.

    DOI: http://doi.org/10.7554/eLife.55684
    Journal: Elife
    E-pub date: 4 Aug 2020
    Authors: S Trakoshis, P Martínez-Cañada, F Rocchi, C Canella, W You, B Chakrabarti, AN Ruigrok, ET Bullmore, J Suckling, M Markicevic, V Zerbi, MRC AIMS Consortium, S Baron-Cohen, A Gozzi, M-C Lai, S Panzeri, MV Lombardo

    Brain networks underlying vulnerability and resilience to drug addiction.

    DOI: http://doi.org/10.1073/pnas.2002509117
    Journal: Proc Natl Acad Sci U S A
    E-pub date: 30 Jun 2020
    Authors: KD Ersche, C Meng, H Ziauddeen, J Stochl, GB Williams, ET Bullmore, TW Robbins

    Greater cortical thickness in individuals with ASD.

    DOI: http://doi.org/10.1038/s41380-020-0691-y
    Journal: Mol Psychiatry
    E-pub date: 1 Mar 2020
    Authors: SA Bedford, MTM Park, GA Devenyi, S Tullo, J Germann, R Patel, E Anagnostou, S Baron-Cohen, ET Bullmore, LR Chura, MC Craig, C Ecker, DL Floris, RJ Holt, R Lenroot, JP Lerch, MV Lombardo, DGM Murphy, A Raznahan, ANV Ruigrok, E Smith, MD Spencer, J Suckling, MJ Taylor, A Thurm, MRC AIMS Consortium, M-C Lai, MM Chakravarty

    Large-scale analyses of the relationship between sex, age and intelligence quotient heterogeneity and cortical morphometry in autism spectrum disorder.

    DOI: http://doi.org/10.1038/s41380-019-0420-6
    Journal: Mol Psychiatry
    E-pub date: 1 Mar 2020
    Authors: SA Bedford, MTM Park, GA Devenyi, S Tullo, J Germann, R Patel, E Anagnostou, S Baron-Cohen, ET Bullmore, LR Chura, MC Craig, C Ecker, DL Floris, RJ Holt, R Lenroot, JP Lerch, MV Lombardo, DGM Murphy, A Raznahan, ANV Ruigrok, E Smith, MD Spencer, J Suckling, MJ Taylor, A Thurm, MRC AIMS Consortium, M-C Lai, MM Chakravarty

    Reorganisation of Brain Hubs across Altered States of Consciousness.

    DOI: http://doi.org/10.1038/s41598-020-60258-1
    Journal: Sci Rep
    E-pub date: 25 Feb 2020
    Authors: D Vatansever, M Schröter, RM Adapa, ET Bullmore, DK Menon, EA Stamatakis

    Enhancement of indirect functional connections with shortest path length in the adult autistic brain.

    DOI: http://doi.org/10.1002/hbm.24777
    Journal: Hum Brain Mapp
    E-pub date: 15 Dec 2019
    Authors: X Guo, T Simas, M-C Lai, MV Lombardo, B Chakrabarti, ANV Ruigrok, ET Bullmore, S Baron-Cohen, H Chen, J Suckling, MRC AIMS Consortium

    Perceptual and conceptual processing of visual objects across the adult lifespan.

    DOI: http://doi.org/10.1038/s41598-019-50254-5
    Journal: Sci Rep
    E-pub date: 24 Sep 2019
    Authors: R Bruffaerts, LK Tyler, M Shafto, KA Tsvetanov, Cambridge Centre for Ageing and Neuroscience, A Clarke

    Dopaminergic modulation of reinforcement learning in stimulant drug addiction

    DOI: http://doi.org/10.1016/j.euroneuro.2019.09.191
    Journal: EUROPEAN NEUROPSYCHOPHARMACOLOGY
    E-pub date: 1 Aug 2019
    Authors: TV Lim, RN Cardinal, C Meng, GK Murray, KJ Craig, S Abbott, SS Shabbir, J Suckling, BJ Sahakian, ET Bullmore, TW Robbins, KD Ersche

    The oxytocin receptor gene predicts brain activity during an emotion recognition task in autism

    DOI: http://doi.org/10.1186/s13229-019-0258-4
    Journal: Mol Autism
    E-pub date: 1 Aug 2019
    Authors: F Uzefovsky, R Bethlehem, S Shamay-Tsoory, A Ruigrok, R Holt, M Spencer, L Chura, V Warrier, B Chakrabarti, E Bullmore, J Suckling, D Floris, S Baron-Cohen, J Davis

    Noradrenergic modulation of stopping impulsivity in cocaine use disorder

    DOI: http://doi.org/10.1016/j.euroneuro.2018.11.317
    Journal: EUROPEAN NEUROPSYCHOPHARMACOLOGY
    E-pub date: 1 Aug 2019
    Authors: R Rodrigues, S Morein-Zamir, C Meng, H Ziauddeen, E Fernandez-Egea, R Regenthal, BJ Sahakian, ET Bullmore, TW Robbins, KD Ersche

    Neural self-representation in autistic women and association with ‘compensatory camouflaging’.

    DOI: http://doi.org/10.1177/1362361318807159
    Journal: Autism
    E-pub date: 1 Jul 2019
    Authors: M-C Lai, MV Lombardo, B Chakrabarti, AN Ruigrok, ET Bullmore, J Suckling, B Auyeung, F Happé, P Szatmari, S Baron-Cohen, MRC AIMS Consortium

    Evidence for a Long-Lasting Compulsive Alcohol Seeking Phenotype in Rats.

    DOI: http://doi.org/10.1038/npp.2017.105
    Journal: Neuropsychopharmacology
    E-pub date: 1 Mar 2018
    Authors: C Giuliano, Y Peña-Oliver, CR Goodlett, RN Cardinal, TW Robbins, ET Bullmore, D Belin, BJ Everitt

    Opioid Antagonists and the A118G Polymorphism in the μ-Opioid Receptor Gene: Effects of GSK1521498 and Naltrexone in Healthy Drinkers Stratified by OPRM1 Genotype.

    DOI: http://doi.org/10.1038/npp.2017.287
    Journal: Neuropsychopharmacology
    E-pub date: 1 Mar 2018
    Authors: H Ziauddeen, LJ Nestor, N Subramaniam, C Dodds, PJ Nathan, SR Miller, BK Sarai, K Maltby, D Fernando, L Warren, LK Hosking, D Waterworth, A Korzeniowska, B Win, DB Richards, LV Johnson, PC Fletcher, ET Bullmore

    Shared and Disorder-Specific Neurocomputational Mechanisms of Decision-Making in Autism Spectrum Disorder and Obsessive-Compulsive Disorder.

    DOI: http://doi.org/10.1093/cercor/bhx265
    Journal: Cereb Cortex
    E-pub date: 1 Dec 2017
    Authors: CO Carlisi, L Norman, CM Murphy, A Christakou, K Chantiluke, V Giampietro, A Simmons, M Brammer, DG Murphy, D Mataix-Cols, K Rubia, MRC AIMS consortium

    Adolescent friendships predict later resilient functioning across psychosocial domains in a healthy community cohort.

    DOI: http://doi.org/10.1017/S0033291717000836
    Journal: Psychol Med
    E-pub date: 1 Oct 2017
    Authors: A-L van Harmelen, RA Kievit, K Ioannidis, S Neufeld, PB Jones, E Bullmore, R Dolan, NSPN Consortium, P Fonagy, I Goodyer

    Atomoxetine effects on attentional bias to drug-related cues in cocaine dependent individuals.

    DOI: http://doi.org/10.1007/s00213-017-4643-4
    Journal: Psychopharmacology (Berl)
    E-pub date: 31 Aug 2017
    Authors: L Passamonti, M Luijten, H Ziauddeen, ITS Coyle-Gilchrist, T Rittman, SAE Brain, R Regenthal, IHA Franken, BJ Sahakian, ET Bullmore, TW Robbins, KD Ersche

    Characterising the latent structure and organisation of self-reported thoughts, feelings and behaviours in adolescents and young adults.

    DOI: http://doi.org/10.1371/journal.pone.0175381
    Journal: PLoS One
    E-pub date: 1 Aug 2017
    Authors: MC St Clair, S Neufeld, PB Jones, P Fonagy, ET Bullmore, RJ Dolan, M Moutoussis, U Toseeb, IM Goodyer

    THE OXYTOCIN RECEPTOR INTERACTS WITH AUTISM DIAGNOSIS TO PREDICT BRAIN ACTIVATION IN RESPONSE TO THE EYES TEST

    DOI: http://doi.org/10.1016/j.euroneuro.2016.09.403
    Journal: EUROPEAN NEUROPSYCHOPHARMACOLOGY
    E-pub date: 1 Aug 2017
    Authors: F Uzefovsky, R Bethlehem, S Shamay-Tsoory, A Ruigrok, R Holt, M Spencer, L Chura, V Warrier, B Chakrabarti, E Bullmore, J Suckling, D Floris, S Baron-Cohen

    Adolescence is Associated with Genomically Patterned Consolidation of the Hubs of the Human Brain Connectome

    DOI: http://doi.org/10.1016/j.biopsych.2017.02.390
    Journal: BIOLOGICAL PSYCHIATRY
    E-pub date: 1 Aug 2017
    Authors: K Whitaker, P Vertes, R Romero-Garcia, F Vasa, M Moutoussis, G Prabhub, N Weiskopf, M Callaghan, K Wagstyl, T Rittman, R Tait, C Ooi, J Suckling, B Inkster, P Fonagy, R Dolan, P Jones, I Goodyer, E Bullmore

    SLC6A2 genotype variation and the modulatory effects of atomoxetine on inhibitory control in individuals with and without cocaine use disorder

    DOI: http://doi.org/10.1016/S0924-977X(17)31865-5
    Journal: EUROPEAN NEUROPSYCHOPHARMACOLOGY
    E-pub date: 1 Aug 2017
    Authors: AN Le, H Ziauddeen, E Fernandez-Egea, R Regenthal, BJ Sahakian, ET Bullmore, TW Robbins, KD Ersche

    Intra-cortical myelination during adolescence: linking MRI networks with gene transcription profiles

    DOI: http://doi.org/10.1016/S0924-977X(17)31087-8
    Journal: EUROPEAN NEUROPSYCHOPHARMACOLOGY
    E-pub date: 1 Aug 2017
    Authors: K Whitaker, P Vertes, R Romero-Garcia, F Vasa, M Moutoussis, G Prabhu, N Weiskopf, MF Callaghan, K Wagstyl, T Rittman, R Tait, C Ooi, J Suckling, B Inkster, P Fonagy, RJ Dolan, PB Jones, IM Goodyer, ET Bullmore

    Structural Covariance Networks in Children with Autism or ADHD.

    DOI: http://doi.org/10.1093/cercor/bhx135
    Journal: Cereb Cortex
    E-pub date: 1 Aug 2017
    Authors: RAI Bethlehem, R Romero-Garcia, E Mak, ET Bullmore, S Baron-Cohen

    Sex differences in frontal lobe connectivity in adults with autism spectrum conditions.

    DOI: http://doi.org/10.1038/tp.2017.9
    Journal: Transl Psychiatry
    E-pub date: 11 Apr 2017
    Authors: EA Zeestraten, MC Gudbrandsen, E Daly, MT de Schotten, M Catani, F Dell'Acqua, M-C Lai, ANV Ruigrok, MV Lombardo, B Chakrabarti, S Baron-Cohen, C Ecker, MRC AIMS Consortium, DGM Murphy, MC Craig

    Association Between the Probability of Autism Spectrum Disorder and Normative Sex-Related Phenotypic Diversity in Brain Structure.

    DOI: http://doi.org/10.1001/jamapsychiatry.2016.3990
    Journal: JAMA Psychiatry
    E-pub date: 1 Apr 2017
    Authors: C Ecker, DS Andrews, CM Gudbrandsen, AF Marquand, CE Ginestet, EM Daly, CM Murphy, M-C Lai, MV Lombardo, ANV Ruigrok, ET Bullmore, J Suckling, SCR Williams, S Baron-Cohen, MC Craig, DGM Murphy, Medical Research Council Autism Imaging Multicentre Study (MRC AIMS) Consortium

    On the brain structure heterogeneity of autism: Parsing out acquisition site effects with significance-weighted principal component analysis.

    DOI: http://doi.org/10.1002/hbm.23449
    Journal: Hum Brain Mapp
    E-pub date: 1 Mar 2017
    Authors: FJ Martinez-Murcia, M-C Lai, JM Górriz, J Ramírez, AMH Young, SCL Deoni, C Ecker, MV Lombardo, MRC AIMS Consortium,, S Baron-Cohen, DGM Murphy, ET Bullmore, J Suckling

    Structural covariance networks in children with autism or ADHD

    DOI: http://doi.org/10.1101/110643
    Journal:
    E-pub date: 21 Feb 2017
    Authors: RAI Bethlehem, R Romero-Garcia, E Mak, ET Bullmore, S Baron-Cohen

    In Vivo Evidence of Reduced Integrity of the Gray-White Matter Boundary in Autism Spectrum Disorder.

    DOI: http://doi.org/10.1093/cercor/bhw404
    Journal: Cereb Cortex
    E-pub date: 1 Feb 2017
    Authors: DS Andrews, TA Avino, M Gudbrandsen, E Daly, A Marquand, CM Murphy, M-C Lai, MV Lombardo, ANV Ruigrok, SC Williams, ET Bullmore, The Mrc Aims Consortium, J Suckling, S Baron-Cohen, MC Craig, DGM Murphy, C Ecker

    Regional expression of the MAPT gene is associated with loss of hubs in brain networks and cognitive impairment in Parkinson disease and progressive supranuclear palsy.

    DOI: http://doi.org/10.1016/j.neurobiolaging.2016.09.001
    Journal: Neurobiol Aging
    E-pub date: 1 Dec 2016
    Authors: T Rittman, M Rubinov, PE Vértes, AX Patel, CE Ginestet, BCP Ghosh, RA Barker, MG Spillantini, ET Bullmore, JB Rowe

    Improving effect size estimation and statistical power with multi-echo fMRI and its impact on understanding the neural systems supporting mentalizing.

    DOI: http://doi.org/10.1016/j.neuroimage.2016.07.022
    Journal: Neuroimage
    E-pub date: 15 Nov 2016
    Authors: MV Lombardo, B Auyeung, RJ Holt, J Waldman, ANV Ruigrok, N Mooney, ET Bullmore, S Baron-Cohen, P Kundu

    Unsupervised data-driven stratification of mentalizing heterogeneity in autism.

    DOI: http://doi.org/10.1038/srep35333
    Journal: Sci Rep
    E-pub date: 18 Oct 2016
    Authors: MV Lombardo, M-C Lai, B Auyeung, RJ Holt, C Allison, P Smith, B Chakrabarti, ANV Ruigrok, J Suckling, ET Bullmore, MRC AIMS Consortium, C Ecker, MC Craig, DGM Murphy, F Happé, S Baron-Cohen

    Gene transcription profiles associated with inter-modular hubs and connection distance in human functional magnetic resonance imaging networks.

    DOI: http://doi.org/10.1098/rstb.2015.0362
    Journal: Philos Trans R Soc Lond B Biol Sci
    E-pub date: 5 Oct 2016
    Authors: PE Vértes, T Rittman, KJ Whitaker, R Romero-Garcia, F Váša, MG Kitzbichler, K Wagstyl, P Fonagy, RJ Dolan, PB Jones, IM Goodyer, NSPN Consortium, ET Bullmore

    Opioid Antagonists and the A118G Polymorphism in the μ-Opioid Receptor Gene: Effects of GSK1521498 and Naltrexone in Healthy Drinkers Stratified by OPRM1 Genotype.

    DOI: http://doi.org/10.1038/npp.2016.60
    Journal: Neuropsychopharmacology
    E-pub date: 1 Oct 2016
    Authors: H Ziauddeen, LJ Nestor, N Subramaniam, C Dodds, PJ Nathan, SR Miller, BK Sarai, K Maltby, D Fernando, L Warren, LK Hosking, D Waterworth, A Korzeniowska, B Win, DB Richards, L Vasist Johnson, PC Fletcher, ET Bullmore

    Adolescence is associated with genomically patterned consolidation of the hubs of the human brain connectome.

    DOI: http://doi.org/10.1073/pnas.1601745113
    Journal: Proc Natl Acad Sci U S A
    E-pub date: 9 Aug 2016
    Authors: KJ Whitaker, PE Vértes, R Romero-Garcia, F Váša, M Moutoussis, G Prabhu, N Weiskopf, MF Callaghan, K Wagstyl, T Rittman, R Tait, C Ooi, J Suckling, B Inkster, P Fonagy, RJ Dolan, PB Jones, IM Goodyer, NSPN Consortium, ET Bullmore

    Default Mode Hypoconnectivity Underlies a Sex-Related Autism Spectrum.

    DOI: http://doi.org/10.1016/j.bpsc.2016.04.006
    Journal: Biol Psychiatry Cogn Neurosci Neuroimaging
    E-pub date: 1 Jul 2016
    Authors: RJF Ypma, RL Moseley, RJ Holt, N Rughooputh, DL Floris, LR Chura, MD Spencer, S Baron-Cohen, J Suckling, ET Bullmore, M Rubinov

    Relationship Between Cortical Gyrification, White Matter Connectivity, and Autism Spectrum Disorder.

    DOI: http://doi.org/10.1093/cercor/bhw098
    Journal: Cereb Cortex
    E-pub date: 1 Jul 2016
    Authors: C Ecker, D Andrews, F Dell'Acqua, E Daly, C Murphy, M Catani, M Thiebaut de Schotten, S Baron-Cohen, MC Lai, MV Lombardo, ET Bullmore, J Suckling, S Williams, DK Jones, A Chiocchetti, MRC AIMS Consortium, DGM Murphy

    Increased body mass index is associated with specific regional alterations in brain structure.

    DOI: http://doi.org/10.1038/ijo.2016.42
    Journal: Int J Obes (Lond)
    E-pub date: 1 Jul 2016
    Authors: N Medic, H Ziauddeen, KD Ersche, IS Farooqi, ET Bullmore, PJ Nathan, L Ronan, PC Fletcher

    Carrots and sticks fail to change behavior in cocaine addiction.

    DOI: http://doi.org/10.1126/science.aaf3700
    Journal: Science
    E-pub date: 17 Jun 2016
    Authors: KD Ersche, CM Gillan, PS Jones, GB Williams, LHE Ward, M Luijten, S de Wit, BJ Sahakian, ET Bullmore, TW Robbins

    Frontal networks in adults with autism spectrum disorder.

    DOI: http://doi.org/10.1093/brain/awv351
    Journal: Brain
    E-pub date: 1 Feb 2016
    Authors: M Catani, F Dell'Acqua, S Budisavljevic, H Howells, M Thiebaut de Schotten, S Froudist-Walsh, L D'Anna, A Thompson, S Sandrone, ET Bullmore, J Suckling, S Baron-Cohen, MV Lombardo, SJ Wheelwright, B Chakrabarti, M-C Lai, ANV Ruigrok, A Leemans, C Ecker, MA Consortium, MC Craig, DGM Murphy

    Atypically rightward cerebral asymmetry in male adults with autism stratifies individuals with and without language delay.

    DOI: http://doi.org/10.1002/hbm.23023
    Journal: Hum Brain Mapp
    E-pub date: 1 Jan 2016
    Authors: DL Floris, M-C Lai, T Auer, MV Lombardo, C Ecker, B Chakrabarti, SJ Wheelwright, ET Bullmore, DGM Murphy, S Baron-Cohen, J Suckling

    Obsessive-Compulsive Disorder in Adults with High-Functioning Autism Spectrum Disorder: What Does Self-Report with the OCI-R Tell Us?

    DOI: http://doi.org/10.1002/aur.1461
    Journal: Autism Res
    E-pub date: 1 Oct 2015
    Authors: T Cadman, D Spain, P Johnston, A Russell, D Mataix-Cols, M Craig, Q Deeley, D Robertson, C Murphy, N Gillan, CE Wilson, M Mendez, C Ecker, E Daly, J Findon, K Glaser, MRC AIMS Consortium, F Happé, D Murphy

    Relationship Between Surface-Based Brain Morphometric Measures and Intelligence in Autism Spectrum Disorders: Influence of History of Language Delay.

    DOI: http://doi.org/10.1002/aur.1470
    Journal: Autism Res
    E-pub date: 1 Oct 2015
    Authors: JB Balardin, JR Sato, G Vieira, Y Feng, E Daly, C Murphy, MRC AIMS Consortium, D Murphy, C Ecker

    Decreased centrality of cortical volume covariance networks in autism spectrum disorders.

    DOI: http://doi.org/10.1016/j.jpsychires.2015.08.003
    Journal: J Psychiatr Res
    E-pub date: 1 Oct 2015
    Authors: JB Balardin, WE Comfort, E Daly, C Murphy, D Andrews, DGM Murphy, C Ecker, MRC AIMS Consortium, JR Sato

    Neuroanatomy of Individual Differences in Language in Adult Males with Autism.

    DOI: http://doi.org/10.1093/cercor/bhu211
    Journal: Cereb Cortex
    E-pub date: 1 Oct 2015
    Authors: M-C Lai, MV Lombardo, C Ecker, B Chakrabarti, J Suckling, ET Bullmore, F Happé, MRC AIMS Consortium, DGM Murphy, S Baron-Cohen

    Whole-brain functional hypoconnectivity as an endophenotype of autism in adolescents.

    DOI: http://doi.org/10.1016/j.nicl.2015.07.015
    Journal: Neuroimage Clin
    E-pub date: 1 Aug 2015
    Authors: RL Moseley, RJF Ypma, RJ Holt, D Floris, LR Chura, MD Spencer, S Baron-Cohen, J Suckling, E Bullmore, M Rubinov

    Semi-Metric Topology of the Human Connectome: Sensitivity and Specificity to Autism and Major Depressive Disorder.

    DOI: http://doi.org/10.1371/journal.pone.0136388
    Journal: PLoS One
    E-pub date: 1 Aug 2015
    Authors: T Simas, S Chattopadhyay, C Hagan, P Kundu, A Patel, R Holt, D Floris, J Graham, C Ooi, R Tait, M Spencer, S Baron-Cohen, B Sahakian, E Bullmore, I Goodyer, J Suckling

    Atomoxetine reduces attentional bias to cocaine-related cues irrespective of norepinephrine transporter gene polymorphism

    DOI: http://doi.org/10.1016/S0924-977X(15)30881-6
    Journal: EUROPEAN NEUROPSYCHOPHARMACOLOGY
    E-pub date: 1 Aug 2015
    Authors: CH Popham, M Luijten, H Ziauddeen, SAE Brain, R Regenthal, IH Franken, BJ Sahakian, ET Bullmore, TW Robbins, KE Ersche

    Investigating ‘waiting impulsivity’ in cocaine addiction: are the effects of atomoxetine mediated by genotype?

    DOI: http://doi.org/10.1016/S0924-977X(15)30875-0
    Journal: EUROPEAN NEUROPSYCHOPHARMACOLOGY
    E-pub date: 1 Aug 2015
    Authors: MI Pollard, H Ziauddeen, IT Coyle-Gilchrist, T Rittman, R Regenthal, S Abbott, BJ Sahakian, ET Bullmore, TW Robbins, KD Ersche

    Emergence of rich-club topology and coordinated dynamics in development of hippocampal functional networks in vitro.

    DOI: http://doi.org/10.1523/JNEUROSCI.4259-14.2015
    Journal: J Neurosci
    E-pub date: 8 Apr 2015
    Authors: MS Schroeter, P Charlesworth, MG Kitzbichler, O Paulsen, ET Bullmore

    White-matter relaxation time and myelin water fraction differences in young adults with autism.

    DOI: http://doi.org/10.1017/S0033291714001858
    Journal: Psychol Med
    E-pub date: 1 Mar 2015
    Authors: SCL Deoni, JR Zinkstok, E Daly, C Ecker, MRC AIMS Consortium, SCR Williams, DGM Murphy

    Distinct aspects of frontal lobe structure mediate age-related differences in fluid intelligence and multitasking.

    DOI: http://doi.org/10.1038/ncomms6658
    Journal: Nat Commun
    E-pub date: 18 Dec 2014
    Authors: RA Kievit, SW Davis, DJ Mitchell, JR Taylor, J Duncan, Cam-CAN Research Team, RNA Henson, Cam-CAN Research Team

    ‘Reading the Mind in the Eyes’: an fMRI study of adolescents with autism and their siblings.

    DOI: http://doi.org/10.1017/S0033291714000233
    Journal: Psychological Medicine
    E-pub date: 12 Nov 2014
    Authors: RJ Holt, LR Chura, M-C Lai, J Suckling, E von dem Hagen, AJ Calder, ET Bullmore, S Baron-Cohen, MD Spencer

    Abnormal functional activation and maturation of fronto-striato-temporal and cerebellar regions during sustained attention in autism spectrum disorder.

    DOI: http://doi.org/10.1176/appi.ajp.2014.12030352
    Journal: Am J Psychiatry
    E-pub date: 1 Oct 2014
    Authors: CM Murphy, A Christakou, EM Daly, C Ecker, V Giampietro, M Brammer, AB Smith, P Johnston, DM Robertson, MRC AIMS Consortium, DG Murphy, K Rubia

    The neuropsychology of male adults with high-functioning autism or asperger syndrome.

    DOI: http://doi.org/10.1002/aur.1394
    Journal: Autism Res
    E-pub date: 1 Oct 2014
    Authors: CE Wilson, F Happé, SJ Wheelwright, C Ecker, MV Lombardo, P Johnston, E Daly, CM Murphy, D Spain, M-C Lai, B Chakrabarti, DA Sauter, MRC AIMS Consortium, S Baron-Cohen, DGM Murphy

    Effects of the mu-opioid receptor antagonist GSK1521498 on hedonic and consummatory eating behaviour: a proof of mechanism study in binge-eating obese subjects

    DOI: http://doi.org/10.1038/mp.2014.126
    Journal: Molecular Psychiatry
    E-pub date: 30 Sep 2014
    Authors: H Ziauddeen, SR Chamberlain, PJ Nathan, A Koch, K Maltby, M Bush, WX Tao, A Napolitano, AL Skeggs, AC Brooke, L Cheke, NS Clayton, I Sadaf Farooqi, S O'Rahilly, D Waterworth, K Song, L Hosking, DB Richards, PC Fletcher, ET Bullmore

    Disorder-specific functional abnormalities during temporal discounting in youth with Attention Deficit Hyperactivity Disorder (ADHD), Autism and comorbid ADHD and Autism.

    DOI: http://doi.org/10.1016/j.pscychresns.2014.04.006
    Journal: Psychiatry Res
    E-pub date: 30 Aug 2014
    Authors: K Chantiluke, A Christakou, CM Murphy, V Giampietro, EM Daly, C Ecker, M Brammer, DG Murphy, MRC AIMS Consortium, K Rubia

    Distribution of tract deficits in schizophrenia.

    DOI: http://doi.org/10.1186/1471-244X-14-99
    Journal: BMC Psychiatry
    E-pub date: 2 Apr 2014
    Authors: I Ellison-Wright, PJ Nathan, ET Bullmore, R Zaman, RB Dudas, M Agius, E Fernandez-Egea, U Müller, CM Dodds, NJ Forde, C Scanlon, A Leemans, C McDonald, DM Cannon

    Immunologic therapeutics and psychotic disorders.

    DOI: http://doi.org/10.1016/j.biopsych.2013.12.006
    Journal: Biol Psychiatry
    E-pub date: 15 Feb 2014
    Authors: ET Bullmore, M-E Lynall

    Measuring “waiting” impulsivity in substance addictions and binge eating disorder in a novel analogue of rodent serial reaction time task.

    DOI: http://doi.org/10.1016/j.biopsych.2013.05.013
    Journal: Biological Psychiatry
    E-pub date: 15 Jan 2014
    Authors: V Voon, MA Irvine, K Derbyshire, Y Worbe, I Lange, S Abbott, S Morein-Zamir, R Dudley, D Caprioli, NA Harrison, J Wood, JW Dalley, ET Bullmore, JE Grant, TW Robbins

    Are power calculations useful? A multicentre neuroimaging study.

    DOI: http://doi.org/10.1002/hbm.22465
    Journal: Human Brain Mapping
    E-pub date: 1 Jan 2014
    Authors: J Suckling, J Henty, C Ecker, SC Deoni, MV Lombardo, S Baron-Cohen, P Jezzard, A Barnes, B Chakrabarti, C Ooi, M-C Lai, SC Williams, DGM Murphy, E Bullmore, MRC AIMS Consortium

    Effects of the mu-opioid receptor antagonist GSK1521498 on hedonic and consummatory eating behaviour: a proof of mechanism study in binge-eating obese subjects.

    DOI: http://doi.org/10.1038/mp.2012.154
    Journal: Mol Psychiatry
    E-pub date: 1 Dec 2013
    Authors: H Ziauddeen, SR Chamberlain, PJ Nathan, A Koch, K Maltby, M Bush, WX Tao, A Napolitano, AL Skeggs, AC Brooke, L Cheke, NS Clayton, I Sadaf Farooqi, S O'Rahilly, D Waterworth, K Song, L Hosking, DB Richards, PC Fletcher, ET Bullmore

    The effects of alcohol on the pharmacokinetics and pharmacodynamics of the selective mu-opioid receptor antagonist GSK1521498 in healthy subjects.

    DOI: http://doi.org/10.1002/jcph.110
    Journal: J Clin Pharmacol
    E-pub date: 1 Oct 2013
    Authors: H Ziauddeen, PJ Nathan, C Dodds, K Maltby, SR Miller, D Waterworth, K Song, L Warren, L Hosking, M Zucchetto, M Bush, LV Johnson, B Sarai, K Mogg, BP Bradley, DB Richards, PC Fletcher, ET Bullmore

    Biological sex affects the neurobiology of autism.

    DOI: http://doi.org/10.1093/brain/awt216
    Journal: Brain
    E-pub date: 1 Sep 2013
    Authors: M-C Lai, MV Lombardo, J Suckling, ANV Ruigrok, B Chakrabarti, C Ecker, SCL Deoni, MC Craig, DGM Murphy, ET Bullmore, MRC AIMS Consortium, S Baron-Cohen

    Prefrontal hypoactivity associated with impaired inhibition in stimulant-dependent individuals but evidence for hyperactivation in their unaffected siblings.

    DOI: http://doi.org/10.1038/npp.2013.90
    Journal: Neuropsychopharmacology
    E-pub date: 1 Sep 2013
    Authors: S Morein-Zamir, P Simon Jones, ET Bullmore, TW Robbins, KD Ersche

    Intrinsic gray-matter connectivity of the brain in adults with autism spectrum disorder.

    DOI: http://doi.org/10.1073/pnas.1221880110
    Journal: Proc Natl Acad Sci U S A
    E-pub date: 6 Aug 2013
    Authors: C Ecker, L Ronan, Y Feng, E Daly, C Murphy, CE Ginestet, M Brammer, PC Fletcher, ET Bullmore, J Suckling, S Baron-Cohen, S Williams, E Loth, MRC AIMS Consortium, DGM Murphy

    Oscillatory underpinnings of mismatch negativity and their relationship with cognitive function in patients with schizophrenia.

    DOI: http://doi.org/10.1371/journal.pone.0083255
    Journal: PLoS One
    E-pub date: 1 Aug 2013
    Authors: M Kaser, F Soltesz, P Lawrence, S Miller, C Dodds, R Croft, RB Dudas, R Zaman, E Fernandez-Egea, U Müller, A Dean, ET Bullmore, PJ Nathan

    Psychological correlates of handedness and corpus callosum asymmetry in autism: the left hemisphere dysfunction theory revisited.

    DOI: http://doi.org/10.1007/s10803-012-1720-8
    Journal: Journal of Autism and Developmental Disorders
    E-pub date: 1 Aug 2013
    Authors: DL Floris, LR Chura, RJ Holt, J Suckling, ET Bullmore, S Baron-Cohen, MD Spencer

    Neural and behavioral effects of a novel mu opioid receptor antagonist in binge-eating obese people.

    DOI: http://doi.org/10.1016/j.biopsych.2012.10.022
    Journal: Biological Psychiatry
    E-pub date: 1 May 2013
    Authors: VC Cambridge, H Ziauddeen, PJ Nathan, N Subramaniam, C Dodds, SR Chamberlain, A Koch, K Maltby, AL Skeggs, A Napolitano, IS Farooqi, ET Bullmore, PC Fletcher

    Inter-regional cortical thickness correlations are associated with autistic symptoms: a machine-learning approach.

    DOI: http://doi.org/10.1016/j.jpsychires.2012.11.017
    Journal: J Psychiatr Res
    E-pub date: 1 Apr 2013
    Authors: JR Sato, MQ Hoexter, PPDM Oliveira, MJ Brammer, MRC AIMS Consortium, D Murphy, C Ecker

    Brain surface anatomy in adults with autism: the relationship between surface area, cortical thickness, and autistic symptoms.

    DOI: http://doi.org/10.1001/jamapsychiatry.2013.265
    Journal: JAMA Psychiatry
    E-pub date: 1 Jan 2013
    Authors: C Ecker, C Ginestet, Y Feng, P Johnston, MV Lombardo, M-C Lai, J Suckling, L Palaniyappan, E Daly, CM Murphy, SC Williams, ET Bullmore, S Baron-Cohen, M Brammer, DGM Murphy, MRC AIMS Consortium

    Failure to deactivate the default mode network indicates a possible endophenotype of autism.

    DOI: http://doi.org/10.1186/2040-2392-3-15
    Journal: Mol Autism
    E-pub date: 3 Dec 2012
    Authors: MD Spencer, LR Chura, RJ Holt, J Suckling, AJ Calder, ET Bullmore, S Baron-Cohen

    Fetal programming effects of testosterone on the reward system and behavioral approach tendencies in humans.

    DOI: http://doi.org/10.1016/j.biopsych.2012.05.027
    Journal: Biological Psychiatry
    E-pub date: 15 Nov 2012
    Authors: MV Lombardo, E Ashwin, B Auyeung, B Chakrabarti, M-C Lai, K Taylor, G Hackett, ET Bullmore, S Baron-Cohen

    Cognition in males and females with autism: similarities and differences.

    DOI: http://doi.org/10.1371/journal.pone.0047198
    Journal: PLoS One
    E-pub date: 1 Aug 2012
    Authors: M-C Lai, MV Lombardo, ANV Ruigrok, B Chakrabarti, SJ Wheelwright, B Auyeung, C Allison, MRC AIMS Consortium, S Baron-Cohen

    Individual differences in brain structure underpin empathizing-systemizing cognitive styles in male adults.

    DOI: http://doi.org/10.1016/j.neuroimage.2012.03.018
    Journal: Neuroimage
    E-pub date: 16 Jul 2012
    Authors: M-C Lai, MV Lombardo, B Chakrabarti, C Ecker, SA Sadek, SJ Wheelwright, DGM Murphy, J Suckling, ET Bullmore, MRC AIMS Consortium, S Baron-Cohen

    Abnormal brain structure implicated in stimulant drug addiction.

    DOI: http://doi.org/10.1126/science.1214463
    Journal: Science
    E-pub date: 3 Feb 2012
    Authors: KD Ersche, PS Jones, GB Williams, AJ Turton, TW Robbins, ET Bullmore

    White matter microstructural abnormalities in the frontal lobe of adults with antisocial personality disorder.

    DOI: http://doi.org/10.1016/j.cortex.2011.06.005
    Journal: Cortex
    E-pub date: 1 Feb 2012
    Authors: F Sundram, Q Deeley, S Sarkar, E Daly, R Latham, M Craig, M Raczek, T Fahy, M Picchioni, UK AIMS Network, GJ Barker, DGM Murphy

    Brain anatomy and its relationship to behavior in adults with autism spectrum disorder: a multicenter magnetic resonance imaging study.

    DOI: http://doi.org/10.1001/archgenpsychiatry.2011.1251
    Journal: Archives of General Psychiatry
    E-pub date: 1 Feb 2012
    Authors: C Ecker, J Suckling, SC Deoni, MV Lombardo, ET Bullmore, S Baron-Cohen, M Catani, P Jezzard, A Barnes, AJ Bailey, SC Williams, DGM Murphy, MRC AIMS Consortium

    Atypical activation during the Embedded Figures Task as a functional magnetic resonance imaging endophenotype of autism.

    DOI: http://doi.org/10.1093/brain/aws229
    Journal: Brain
    E-pub date: 1 Jan 2012
    Authors: MD Spencer, RJ Holt, LR Chura, AJ Calder, J Suckling, ET Bullmore, S Baron-Cohen

    Variation in the human cannabinoid receptor CNR1 gene modulates gaze duration for happy faces

    DOI: http://doi.org/10.1186/2040-2392-2-10
    Journal: Molecular Autism
    E-pub date: 1 Dec 2011
    Authors: B Chakrabarti, S Baron-Cohen

    A novel functional brain imaging endophenotype of autism: the neural response to facial expression of emotion.

    DOI: http://doi.org/10.1038/tp.2011.18
    Journal: Transl Psychiatry
    E-pub date: 12 Jul 2011
    Authors: MD Spencer, RJ Holt, LR Chura, J Suckling, AJ Calder, ET Bullmore, S Baron-Cohen

    Abnormal structure of frontostriatal brain systems is associated with aspects of impulsivity and compulsivity in cocaine dependence.

    DOI: http://doi.org/10.1093/brain/awr138
    Journal: Brain
    E-pub date: 1 Jul 2011
    Authors: KD Ersche, A Barnes, PS Jones, S Morein-Zamir, TW Robbins, ET Bullmore

    Specialization of right temporo-parietal junction for mentalizing and its relation to social impairments in autism.

    DOI: http://doi.org/10.1016/j.neuroimage.2011.02.067
    Journal: Neuroimage
    E-pub date: 1 Jun 2011
    Authors: MV Lombardo, B Chakrabarti, ET Bullmore, MRC AIMS Consortium, S Baron-Cohen

    A shift to randomness of brain oscillations in people with autism.

    DOI: http://doi.org/10.1016/j.biopsych.2010.06.027
    Journal: Biol Psychiatry
    E-pub date: 15 Dec 2010
    Authors: M-C Lai, MV Lombardo, B Chakrabarti, SA Sadek, G Pasco, SJ Wheelwright, ET Bullmore, S Baron-Cohen, MRC AIMS Consortium, J Suckling

    Impaired visuospatial associative memory and attention in obsessive compulsive disorder but no evidence for differential dopaminergic modulation.

    DOI: http://doi.org/10.1007/s00213-010-1963-z
    Journal: Psychopharmacology (Berl)
    E-pub date: 1 Oct 2010
    Authors: S Morein-Zamir, KJ Craig, KD Ersche, S Abbott, U Muller, NA Fineberg, ET Bullmore, BJ Sahakian, TW Robbins

    Functional connectivity and brain networks in schizophrenia.

    DOI: http://doi.org/10.1523/JNEUROSCI.0333-10.2010
    Journal: J Neurosci
    E-pub date: 14 Jul 2010
    Authors: M-E Lynall, DS Bassett, R Kerwin, PJ McKenna, M Kitzbichler, U Muller, E Bullmore

    Shared neural circuits for mentalizing about the self and others.

    DOI: http://doi.org/10.1162/jocn.2009.21287
    Journal: J Cogn Neurosci
    E-pub date: 1 Jul 2010
    Authors: MV Lombardo, B Chakrabarti, ET Bullmore, SJ Wheelwright, SA Sadek, J Suckling, MRC AIMS Consortium, S Baron-Cohen

    Atypical neural self-representation in autism.

    DOI: http://doi.org/10.1093/brain/awp306
    Journal: Brain
    E-pub date: 1 Feb 2010
    Authors: MV Lombardo, B Chakrabarti, ET Bullmore, SA Sadek, G Pasco, SJ Wheelwright, J Suckling, MRC AIMS Consortium, S Baron-Cohen

    Organizational effects of fetal testosterone on human corpus callosum size and asymmetry.

    DOI: http://doi.org/10.1016/j.psyneuen.2009.09.009
    Journal: Psychoneuroendocrinology
    E-pub date: 1 Jan 2010
    Authors: LR Chura, MV Lombardo, E Ashwin, B Auyeung, B Chakrabarti, ET Bullmore, S Baron-Cohen

    Brain hyper-reactivity to auditory novel targets in children with high-functioning autism.

    DOI: http://doi.org/10.1093/brain/awn172
    Journal: Brain
    E-pub date: 1 Sep 2008
    Authors: M Gomot, MK Belmonte, ET Bullmore, FA Bernard, S Baron-Cohen

    Differential activation of the amygdala and the ‘social brain’ during fearful face-processing in Asperger Syndrome.

    DOI: http://doi.org/10.1016/j.neuropsychologia.2006.04.014
    Journal: Neuropsychologia
    E-pub date: 7 Jan 2007
    Authors: C Ashwin, S Baron-Cohen, S Wheelwright, M O'Riordan, ET Bullmore

    The role of MT+/V5 during biological motion perception in Asperger Syndrome: An fMRI study

    DOI: http://doi.org/10.1016/j.rasd.2006.07.002
    Journal: RES AUTISM SPECT DIS
    E-pub date: 1 Jan 2007
    Authors: JD Herrington, S Baron-Cohen, SJ Wheelwright, KD Singh, EI Bullmore, M Brammer, SCR Williams

    Empathizing with basic emotions: common and discrete neural substrates.

    DOI: http://doi.org/10.1080/17470910601041317
    Journal: Soc Neurosci
    E-pub date: 1 Aug 2006
    Authors: B Chakrabarti, E Bullmore, S Baron-Cohen

    fMRI of parents of children with Asperger Syndrome: a pilot study.

    DOI: http://doi.org/10.1016/j.bandc.2005.12.011
    Journal: Brain Cogn
    E-pub date: 1 Jun 2006
    Authors: S Baron-Cohen, H Ring, X Chitnis, S Wheelwright, L Gregory, S Williams, M Brammer, E Bullmore

    Variations in the human cannabinoid receptor (CNR1) gene modulate striatal responses to happy faces.

    DOI: http://doi.org/10.1111/j.1460-9568.2006.04697.x
    Journal: Eur J Neurosci
    E-pub date: 1 Apr 2006
    Authors: B Chakrabarti, L Kent, J Suckling, E Bullmore, S Baron-Cohen

    Change detection in children with autism: an auditory event-related fMRI study.

    DOI: http://doi.org/10.1016/j.neuroimage.2005.07.027
    Journal: Neuroimage
    E-pub date: 15 Jan 2006
    Authors: M Gomot, FA Bernard, MH Davis, MK Belmonte, C Ashwin, ET Bullmore, S Baron-Cohen

    Impairment of specific episodic memory processes by sub-psychotic doses of ketamine: the effects of levels of processing at encoding and of the subsequent retrieval task.

    DOI: http://doi.org/10.1007/s00213-005-0001-z
    Journal: Psychopharmacology (Berl)
    E-pub date: 1 Sep 2005
    Authors: GD Honey, RAE Honey, SR Sharar, DC Turner, E Pomarol-Clotet, D Kumaran, JS Simons, X Hu, MD Rugg, ET Bullmore, PC Fletcher

    Functional disconnectivity of the medial temporal lobe in Asperger’s syndrome.

    DOI: http://doi.org/10.1016/j.biopsych.2005.01.028
    Journal: Biol Psychiatry
    E-pub date: 1 May 2005
    Authors: DE Welchew, C Ashwin, K Berkouk, R Salvador, J Suckling, S Baron-Cohen, E Bullmore

    The amygdala theory of autism.

    DOI: http://doi.org/10.1016/s0149-7634(00)00011-7
    Journal: Neurosci Biobehav Rev
    E-pub date: 1 May 2000
    Authors: S Baron-Cohen, HA Ring, ET Bullmore, S Wheelwright, C Ashwin, SC Williams

    Cerebral correlates of preserved cognitive skills in autism: a functional MRI study of embedded figures task performance.

    DOI: http://doi.org/10.1093/brain/122.7.1305
    Journal: Brain
    E-pub date: 1 Jul 1999
    Authors: HA Ring, S Baron-Cohen, S Wheelwright, SC Williams, M Brammer, C Andrew, ET Bullmore