Dr Emma Cahill

Interests

My immediate objective is to develop my research in neuronal signalling complexes and apply what I find to unanswered fundamental questions related to memory. In my postdoctoral research, I shall address the signalling requirements of memories associated with drugs of abuse, but also memories of fear. My background in memory and addiction-recruited cellular signalling and behaviour will enable me to reveal new mechanisms of memory processing and commonalities of persistent drug and fear memory.

Research Focus

Keywords

Memory

Addiction

Glutamate

Dopamine

Fear

Clinical conditions

Addiction

Post-traumatic stress disorder

Equipment

Behavioural analysis

Fluorescence microscopy

Immunohistochemistry

Microscopy

Collaborators

Cambridge

Amy Milton

George Vousden

Associated News Items


Publications

2014

Cahill E, Pascoli V, Trifilieff P, Savoldi D, Kappès V, Lüscher C, Caboche J, Vanhoutte P (2014), “D1R/GluN1 complexes in the striatum integrate dopamine and glutamate signalling to control synaptic plasticity and cocaine-induced responses.” Mol Psychiatry 19(12):1295-304 Details

Cahill E, Salery M, Vanhoutte P, Caboche J (2014), “Convergence of dopamine and glutamate signaling onto striatal ERK activation in response to drugs of abuse.” Front Pharmacol 4:172 Details

Pascoli V, Cahill E, Bellivier F, Caboche J, Vanhoutte P (2014), “Extracellular Signal-Regulated Protein Kinases 1 and 2 Activation by Addictive Drugs: A Signal Toward Pathological Adaptation.” Biol Psychiatry Details

2011

Roze E, Cahill E, Martin E, Bonnet C, Vanhoutte P, Betuing S, Caboche J (2011), “Huntington's Disease and Striatal Signaling.” Front Neuroanat 5:55 Details

2008

Larkin AE, Fahey B, Gobbo O, Callaghan CK, Cahill E, O'Mara SM, Kelly AM (2008), “Blockade of NMDA receptors pre-training, but not post-training, impairs object displacement learning in the rat.” Brain Res 1199:126-32 Details