Dr Piers Emson

University position

Emeritus Scientist

Departments

Department of Psychiatry

Institutes

Babraham Institute

Home page

http://www.babraham.ac.uk/researc...

Research Themes

Cellular and Molecular Neuroscience

Cognitive and Behavioural Neuroscience

Interests

Development and testing of models of human neurodegenerative disease and comparison with human post mortem material.

Localisation of PARK8 gene in the mouse brain
Localisation of PARK8 gene in the mouse brain
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Research Focus

Keywords

neurodegeneration

transgenics

neuroanatomy

gene expression

Clinical conditions

Alzheimer's disease

Dementia

Huntington's disease

Movement disorders

Parkinson's disease

Schizophrenia

Equipment

Calcium imaging

Cell culture

Confocal microscopy

Fluorescence microscopy

Immunohistochemistry

Collaborators

Cambridge

Michel Goedert

Barry Keverne

Maria Grazia Spillantini

Lawrence Wilkinson

International

Heii Arai Web: http://www.juntendo.ac.jp/english...

Anders Bjorklund Web: http://www.wnc.se/Members...

Richard Faull Web: http://www.health.auckland.ac.nz/anatomy...

Key publications

Colebrooke RE, Humby T, Lynch PJ, McGowan DP, Xia J, Emson PC (2006), “Age-related decline in striatal dopamine content and motor performance occurs in the absence of nigral cell loss in a genetic mouse model of Parkinson's disease” Eur J Neurosci 24(9):2622-30 Details

Allen JP, Hathway GJ, Clarke NJ, Jowett MI, Topps S, Kendrick KM, Humphrey PP, Wilkinson LS, Emson PC (2003), “Somatostatin receptor 2 knockout/lacZ knockin mice show impaired motor coordination and reveal sites of somatostatin action within the striatum” Eur J Neurosci 17(9):1881-95 Details

Billinton A, Ige AO, Bolam JP, White JH, Marshall FH, Emson PC (2001), “Advances in the molecular understanding of GABA(B) receptors” Trends Neurosci 24(5):277-82