Dr Emad Moeendarbary

Emad Moeendarbary

University position

Herchel Smith Research Fellow

Departments

Department of Physiology, Development and Neuroscience

Email

em429@cam.ac.uk

Home page

http://www.MecBioMed.com (personal home page)

Research Themes

Cellular and Molecular Neuroscience

Developmental Neuroscience

Interests

I am a mechanical engineer with a strong interest in the experimental and ‎theoretical/computational study of biological systems.

Presently, I am working at the ‎interface of engineering and neuroscience to explore mechanics of neurons ‎in the central ‎nervous system.‎ I am also interested in the mechanobiology of cancer metastasis.

AFM cantilever with a spherical tip indenting a cell
AFM cantilever with a spherical tip indenting a cell
Click image to view full-size

Research Focus

Keywords

Mechanobiology

Cell Mechanics

Neuromechanics

Axon Guidance

Cancer Mechanics

Clinical conditions

Cancer Metastasis

Spinal Cord/ Brain Injuries

Traumatic brain injury

Equipment

Atomic Force Microscopy

Computational modelling

Defocusing Microscopy

Microfluidics

Parallel Programming

Traction Force Microscopy

Collaborators

Cambridge

James Fawcett

Kristian Franze

Graham Sheridan

United Kingdom

Guillaume Charras at UCL Web: http://www.london-nano.com/our-peo...

International

Roger Kamm at MIT Web: http://web.mit.edu/meche/mb/

Associated News Items


    Publications

    2015

    Gautier HO, Thompson AJ, Achouri S, Koser DE, Holtzmann K, Moeendarbary E, Franze K (2015), “Atomic force microscopy-based force measurements on animal cells and tissues.” Methods Cell Biol 125:211-35 Details

    Moeendarbary E, Charras G (2015), “Cell mechanics: Hydraulic cracking.” Nat Mater 14(3):268-9 Details

    2014

    Moeendarbary E, Harris AR (2014), “Cell mechanics: principles, practices, and prospects.” Wires SYSTEMS BIOLOGY AND MEDICINE Vol 6 (Issue5) PDF

    Sheridan GK, Moeendarbary E, Pickering M, O'Connor JJ, Murphy KJ (2014), “Theta-burst stimulation of hippocampal slices induces network-level calcium oscillations and activates analogous gene transcription to spatial learning.” PLoS One 9(6):e100546 Details

    2013

    Calvo F, Ege N, Grande-Garcia A, Hooper S, Jenkins RP, Chaudhry SI, Harrington K, Williamson P, Moeendarbary E, Charras G, Sahai E (2013), “Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts.” Nat Cell Biol Details

    Moeendarbary E, Valon L, Fritzsche M, Harris AR, Moulding DA, Thrasher AJ, Stride E, Mahadevan L, Charras GT (2013), “The cytoplasm of living cells behaves as a poroelastic material.” Nat Mater 12(3):253-61 Details

    2012

    Kunda P, Rodrigues NT, Moeendarbary E, Liu T, Ivetic A, Charras G, Baum B (2012), “PP1-mediated moesin dephosphorylation couples polar relaxation to mitotic exit.” Curr Biol 22(3):231-6 PDF Details

    Moulding DA, Moeendarbary E, Valon L, Record J, Charras GT, Thrasher AJ (2012), “Excess F-actin mechanically impedes mitosis leading to cytokinesis failure in X-linked neutropenia by exceeding Aurora B kinase error correction capacity.” Blood 120(18):3803-11 PDF Details

    2010

    Moeendarbary E, Ng TY, Pan H, Lam KY (2010), “Migration of DNA molecules through ‎entropic trap arrays: ‎A dissipative particle dynamics study” Microfluidics and Nanofluidics 8(2):243-254 PDF

    Moeendarbary E, Ng TY, Zangeneh M (2010), “Dissipative particle dynamics in soft matter ‎and polymeric ‎applications” International Journal of Applied ‎Mechanics 2(1):161-190 PDF

    Pan H, Ng TY, Li H, Moeendarbary E (2010), “Dissipative particle dynamics simulation of ‎entropic trapping ‎for DNA separation” Sensors and Actuators, A: Physical 157(2):328-‎‎335 PDF

    2009

    Moeendarbary E, Ng TY, Zangeneh M (2009), “Dissipative particle dynamics: Introduction, ‎methodology ‎and complex fluid applications-a review” International Journal of Applied ‎Mechanics 1(4):737-763 PDF