Dr Dina Kronhaus

Interests

My research is focused on studying connectivity and neural re-organisation, in the human brain, using theoretical modelling techniques to complement analysis of experimental data. I aim to identify overlapping yet distinct neural circuits implicated in processes of memory, emotion and cognitive control. I use computational models to study dynamics of networks and predict how experimental manipulation of network constituents affects overall behaviour.

Research Focus

Keywords

emotion

memory

connectivity

fMRI

neural circuit

Clinical conditions

Bipolar disorder

Dementia

Depressive disorders

Traumatic brain injury

Equipment

Computational modelling

Magnetic resonance imaging (MRI)

Positron Emission Tomography (PET)

Collaborators

Cambridge

Ian Cross

Richard Henson

Guy Williams

International

Mary Phillips Web: http://www.wpic.pitt.edu/researc...

Associated News Items


    Key publications

    Kronhaus DM et al (2006), “Stroop performance in bipolar disorder: further evidence for abnormalities in the ventral prefrontal cortex” Bipolar Disord 8(1):28-39

    Kronhaus DM, Willshaw DJ (2006), “The cingulate as a catalyst region for global dysfunction: a dynamical modelling paradigm” Cereb Cortex 16(8):1212-24 Details

    Publications

    2014

    Stan AD, Schirda CV, Bertocci MA, Bebko GM, Kronhaus DM, Aslam HA, LaBarbara EJ, Tanase C, Lockovich JC, Pollock MH, Stiffler RS, Phillips ML (2014), “Glutamate and GABA contributions to medial prefrontal cortical activity to emotion: Implications for mood disorders.” Psychiatry Res Details

    2013

    Fournier JC, Keener MT, Almeida J, Kronhaus DM, Phillips ML (2013), “Amygdala and whole-brain activity to emotional faces distinguishes major depressive disorder and bipolar disorder.” Bipolar Disord 15(7):741-52 Details

    Fournier JC, Keener MT, Mullin BC, Hafeman DM, Labarbara EJ, Stiffler RS, Almeida J, Kronhaus DM, Frank E, Phillips ML (2013), “Heterogeneity of amygdala response in major depressive disorder: the impact of lifetime subthreshold mania.” Psychol Med 43(2):293-302 Details

    Herringa RJ, Phillips ML, Fournier JC, Kronhaus DM, Germain A (2013), “Childhood and adult trauma both correlate with dorsal anterior cingulate activation to threat in combat veterans.” Psychol Med 43(7):1533-42 Details

    2012

    Keener MT, Fournier JC, Mullin BC, Kronhaus D, Perlman SB, LaBarbara E, Almeida JC, Phillips ML (2012), “Dissociable patterns of medial prefrontal and amygdala activity to face identity versus emotion in bipolar disorder.” Psychol Med 42(9):1913-24 Details

    Perlman SB, Almeida JR, Kronhaus DM, Versace A, Labarbara EJ, Klein CR, Phillips ML (2012), “Amygdala activity and prefrontal cortex-amygdala effective connectivity to emerging emotional faces distinguish remitted and depressed mood states in bipolar disorder.” Bipolar Disord 14(2):162-74 Details

    Radua J, Mataix-Cols D, Phillips ML, El-Hage W, Kronhaus DM, Cardoner N, Surguladze S (2012), “A new meta-analytic method for neuroimaging studies that combines reported peak coordinates and statistical parametric maps.” Eur Psychiatry 27(8):605-11 Details

    Surguladze SA, Radua J, El-Hage W, Gohier B, Sato JR, Kronhaus DM, Proitsi P, Powell J, Phillips ML (2012), “Interaction of catechol O-methyltransferase and serotonin transporter genes modulates effective connectivity in a facial emotion-processing circuitry.” Transl Psychiatry 2:e70 Details

    2011

    Almeida JR, Kronhaus DM, Sibille EL, Langenecker SA, Versace A, Labarbara EJ, Phillips ML (2011), “Abnormal left-sided orbitomedial prefrontal cortical-amygdala connectivity during happy and fear face processing: a potential neural mechanism of female MDD.” Front Psychiatry 2:69 Details

    2009

    Ladouceur CD, Silk JS, Dahl RE, Ostapenko L, Kronhaus DM, Phillips ML (2009), “Fearful faces influence attentional control processes in anxious youth and adults.” Emotion 9(6):855-64 Details

    2006

    Kronhaus DM, Lawrence NS, Williams AM, Frangou S, Brammer MJ, Williams SC, Andrew CM, Phillips ML (2006), “Stroop performance in bipolar disorder: further evidence for abnormalities in the ventral prefrontal cortex.” Bipolar Disord 8(1):28-39 Details