Other Interdiciplinary Incentives
Keywords
Clinical Conditions
Equipment & Techniques
Science Culture
I am a Professor of Biomedical Imaging and Head of 7T MRI Physics. My main expertise is in creating new methods for Magnetic Resonance Imaging (MRI) and Magnetic Resonance Spectroscopy (MRS). My group focus on ultra-high field (7T) MRI using the Siemens 7T Terra MRI scanner at the Wolfson Brain Imaging Centre. We push the boundaries of MRI techniques and translate the latest methods ready for use in clinical studies in collaboration with colleagues in Clinical Neurosciences and elsewhere. My group have active projects in parallel transmit MRI funded by Siemens where we have recently patented two new algorithms to improve the uniformity of 7T MRI and reduce RF heating of participants. We lead the "MITI" study which is testing whether the new drug dapagliflozin acts by restoring cardiac energy metabolism in patients with heart failure and type 2 diabetes. We collaborate with Prof Markus' group to study the mechanisms of cerebral small vessel disease. We collaborate with Prof Brindle and Prof Mair to apply deuterium metabolic imaging in patients with brain tumours. We collaborate with Prof Rowe and Prof O'Brien and Dr Matys to study changes in glycolysis in Alzheimer's disease also using deuterium metabolic imaging. We collaborate with Dr Cope on a study using 7T MRI to help detect the lesions responsible for drug-resistant focal epilepsy. I welcome applications for new PhD students, undergraduate students and for lab visits or summer projects.
Illustration of our new Bayesian Optimisation approach to parallel transmit pulse design - the BOGAT algorithm. This work won a Summa Cum Laude Merit Award at ISMRM 2023.
