Charlotte Rae

Interests

I am a cognitive neuroscientist, investigating the structural and functional brain networks that support human voluntary action. The process of initiating voluntary movements, and then stopping or changing our actions, relies on interactions between the prefrontal cortex, motor regions, and the basal ganglia. I use fMRI (functional magnetic resonance imaging) and diffusion MRI to investigate the functional and structural networks supporting these functions in the human brain. In addition to characterising networks for control of voluntary action in healthy people, I also investigate how neural networks may become abnormal in disorders of voluntary action, such as Parkinson's disease.

"Marylin's Brain" MRI art
Click image to view full-size

Research Focus

Keywords

fMRI

DTI

dynamic causal modelling

voluntary action

Parkinson's disease

Clinical conditions

Parkinson's disease

Equipment

Magnetic resonance imaging (MRI)

Collaborators

Cambridge

Mike Anderson

Marta Correia

Laura Hughes

James Rowe

Noham Wolpe

Associated News Items


    Publications

    2014

    Rae CL, Hughes LE, Weaver C, Anderson MC, Rowe JB (2014), “Selection and stopping in voluntary action: A meta-analysis and combined fMRI study.” Neuroimage 86:381-91 Details

    Wolpe N, Moore JW, Rae CL, Rittman T, Altena E, Haggard P, Rowe JB (2014), “The medial frontal-prefrontal network for altered awareness and control of action in corticobasal syndrome.” Brain 137(Pt 1):208-20 Details

    Ye Z, Altena E, Nombela C, Housden CR, Maxwell H, Rittman T, Huddleston C, Rae CL, Regenthal R, Sahakian BJ, Barker RA, Robbins TW, Rowe JB (2014), “Improving Response Inhibition in Parkinson's Disease with Atomoxetine.” Biol Psychiatry Details

    Ye Z, Altena E, Nombela C, Housden CR, Maxwell H, Rittman T, Huddleston C, Rae CL, Regenthal R, Sahakian BJ, Barker RA, Robbins TW, Rowe JB (2014), “Selective serotonin reuptake inhibition modulates response inhibition in Parkinson's disease.” Brain 137(Pt 4):1145-55 Details

    2013

    Nombela C, Rae CL, Grahn JA, Barker RA, Owen AM, Rowe JB (2013), “How often does music and rhythm improve patients' perception of motor symptoms in Parkinson's disease?” J Neurol 260(5):1404-5 Details

    2012

    Chen JL, Rae C, Watkins KE (2012), “Learning to play a melody: an fMRI study examining the formation of auditory-motor associations.” Neuroimage 59(2):1200-8 Details

    Rae CL, Correia MM, Altena E, Hughes LE, Barker RA, Rowe JB (2012), “White matter pathology in Parkinson's disease: The effect of imaging protocol differences and relevance to executive function.” Neuroimage Details