Dr Ben Seymour
Clinical Research Associate
Dr Ben Seymour is pleased to consider applications from prospective PhD students.
http://www.seymourlab.com (personal home page)
My research addresses the computational and systems neuroscience of pain and aversive learning. This research is part theoretical: building realistic computational models of neuronal information processes to understand processes of pain perception and behaviour, and part experimental: testing these theories using a range of experimental methodologies, especially fMRI.
My interests include:
- Reinforcement learning models of aversive preciction and control (Pavlovian and instrumental learning),
- Models of pain perception and it's modulation,
- Neuroeconomic and social models of pain,
- Brain-machine interfaces for chronic pain,
- Pain and aversive control in artificial and cybernetic systems.
Tipu Aziz Web: http://www.nds.ox.ac.uk/about-n...
Nick Chater Web: http://www.wbs.ac.uk/faculty...
Peter Dayan Web: http://firstname.lastname@example.org
Ray Dolan Web: http://www.fil.ion.ucl.ac.uk/Dolan/
Alex Green Web: http://www.nds.ox.ac.uk/about-n...
Maria Joao Web: http://www.mlnl.cs.ucl.ac.uk/mjrosa/
Rosalyn Moran Web: http://www.fil.ion.ucl.ac.uk/~rmoran/
Ivo Vlaev Web: http://www1.imperial.ac.uk/medicin...
Joel Winston Web: http://www.fil.ion.ucl.ac.uk/~jwinston/
Michael Barbe Web: http://www.sanego.de/Arzt/No...
Gereon Fink Web: http://neurologie-psychiatrie.uk-koeln.de/neurolo...
Michael Frolich Web: http://medicine.uab.edu/anesthe...
Mitsuo Kawato Web: http://www.cns.atr.jp/~kawato/
Kazu Shinata Web: https://sites.google.com/site/ka...
Seymour B (2012), “The maladaptive brain: excitable pathways to chronic pain.” Brain 135(Pt 2):316-8 Details
Seymour B, Daw ND, Roiser JP, Dayan P, Dolan R (2012), “Serotonin selectively modulates reward value in human decision-making.” J Neurosci 32(17):5833-42 Details
Shiner T, Seymour B, Wunderlich K, Hill C, Bhatia KP, Dayan P, Dolan RJ (2012), “Dopamine and performance in a reinforcement learning task: evidence from Parkinson's disease.” Brain Details
Daw ND, Gershman SJ, Seymour B, Dayan P, Dolan RJ (2011), “Model-based influences on humans' choices and striatal prediction errors.” Neuron 69(6):1204-15 Details
Fitzgerald TH, Seymour B, Bach DR, Dolan RJ (2010), “Differentiable neural substrates for learned and described value and risk.” Curr Biol 20(20):1823-9 Details
Pine A, Shiner T, Seymour B, Dolan RJ (2010), “Dopamine, time, and impulsivity in humans.” J Neurosci 30(26):8888-96 Details
Yoshida W, Seymour B, Friston KJ, Dolan RJ (2010), “Neural mechanisms of belief inference during cooperative games.” J Neurosci 30(32):10744-51 Details
Yu R, Mobbs D, Seymour B, Calder AJ (2010), “Insula and striatum mediate the default bias.” J Neurosci 30(44):14702-7 Details
Bach DR, Seymour B, Dolan RJ (2009), “Neural activity associated with the passive prediction of ambiguity and risk for aversive events.” J Neurosci 29(6):1648-56 Details
FitzGerald TH, Seymour B, Dolan RJ (2009), “The role of human orbitofrontal cortex in value comparison for incommensurable objects.” J Neurosci 29(26):8388-95 Details
Mobbs D, Hassabis D, Seymour B, Marchant JL, Weiskopf N, Dolan RJ, Frith CD (2009), “Choking on the money: reward-based performance decrements are associated with midbrain activity.” Psychol Sci 20(8):955-62 Details
Mobbs D, Marchant JL, Hassabis D, Seymour B, Tan G, Gray M, Petrovic P, Dolan RJ, Frith CD (2009), “From threat to fear: the neural organization of defensive fear systems in humans.” J Neurosci 29(39):12236-43 Details
Mobbs D, Yu R, Meyer M, Passamonti L, Seymour B, Calder AJ, Schweizer S, Frith CD, Dalgleish T (2009), “A key role for similarity in vicarious reward.” Science 324(5929):900 Details
Pine A, Seymour B, Roiser JP, Bossaerts P, Friston KJ, Curran HV, Dolan RJ (2009), “Encoding of marginal utility across time in the human brain.” J Neurosci 29(30):9575-81 Details
Roiser JP, de Martino B, Tan GC, Kumaran D, Seymour B, Wood NW, Dolan RJ (2009), “A genetically mediated bias in decision making driven by failure of amygdala control.” J Neurosci 29(18):5985-91 Details
Seymour B, Yoshida W, Dolan R (2009), “Altruistic learning.” Front Behav Neurosci 3:23 Details
Vlaev I, Seymour B, Dolan RJ, Chater N (2009), “The price of pain and the value of suffering.” Psychol Sci 20(3):309-17 Details
Brown CA, Seymour B, Boyle Y, El-Deredy W, Jones AK (2008), “Modulation of pain ratings by expectation and uncertainty: Behavioral characteristics and anticipatory neural correlates.” Pain 135(3):240-50 Details
Brown CA, Seymour B, El-Deredy W, Jones AK (2008), “Confidence in beliefs about pain predicts expectancy effects on pain perception and anticipatory processing in right anterior insula.” Pain 139(2):324-32 Details
Petrovic P, Pleger B, Seymour B, Klöppel S, De Martino B, Critchley H, Dolan RJ (2008), “Blocking central opiate function modulates hedonic impact and anterior cingulate response to rewards and losses.” J Neurosci 28(42):10509-16 Details
Seymour B, Dolan R (2008), “Emotion, decision making, and the amygdala.” Neuron 58(5):662-71 Details
Seymour B, McClure SM (2008), “Anchors, scales and the relative coding of value in the brain.” Curr Opin Neurobiol 18(2):173-8 Details
Talmi D, Seymour B, Dayan P, Dolan RJ (2008), “Human pavlovian-instrumental transfer.” J Neurosci 28(2):360-8 Details
Wittmann BC, Daw ND, Seymour B, Dolan RJ (2008), “Striatal activity underlies novelty-based choice in humans.” Neuron 58(6):967-73 Details
Mobbs D, Petrovic P, Marchant JL, Hassabis D, Weiskopf N, Seymour B, Dolan RJ, Frith CD (2007), “When fear is near: threat imminence elicits prefrontal-periaqueductal gray shifts in humans.” Science 317(5841):1079-83 Details
Seymour B (2007), “Research loses in hasty changes to medical training.” Nature 446(7135):492 Details
Seymour B, Daw N, Dayan P, Singer T, Dolan R (2007), “Differential encoding of losses and gains in the human striatum.” J Neurosci 27(18):4826-31 Details
Seymour B, Singer T, Dolan R (2007), “The neurobiology of punishment.” Nat Rev Neurosci 8(4):300-11 Details
Carter RM, O'Doherty JP, Seymour B, Koch C, Dolan RJ (2006), “Contingency awareness in human aversive conditioning involves the middle frontal gyrus.” Neuroimage 29(3):1007-12 Details
Daw ND, O'Doherty JP, Dayan P, Seymour B, Dolan RJ (2006), “Cortical substrates for exploratory decisions in humans.” Nature 441(7095):876-9 Details
Dayan P, Niv Y, Seymour B, Daw ND (2006), “The misbehavior of value and the discipline of the will.” Neural Netw 19(8):1153-60 Details
De Martino B, Kumaran D, Seymour B, Dolan RJ (2006), “Frames, biases, and rational decision-making in the human brain.” Science 313(5787):684-7 Details
Kalisch R, Korenfeld E, Stephan KE, Weiskopf N, Seymour B, Dolan RJ (2006), “Context-dependent human extinction memory is mediated by a ventromedial prefrontal and hippocampal network.” J Neurosci 26(37):9503-11 Details
O'Doherty JP, Buchanan TW, Seymour B, Dolan RJ (2006), “Predictive neural coding of reward preference involves dissociable responses in human ventral midbrain and ventral striatum.” Neuron 49(1):157-66 Details
Pessiglione M, Seymour B, Flandin G, Dolan RJ, Frith CD (2006), “Dopamine-dependent prediction errors underpin reward-seeking behaviour in humans.” Nature 442(7106):1042-5 Details
Seymour B (2006), “Carry on eating: neural pathways mediating conditioned potentiation of feeding.” J Neurosci 26(4):1061-2; discussion 1062 Details
Singer T, Seymour B, O'Doherty JP, Stephan KE, Dolan RJ, Frith CD (2006), “Empathic neural responses are modulated by the perceived fairness of others.” Nature 439(7075):466-9 Details
Kalisch R, Wiech K, Critchley HD, Seymour B, O'Doherty JP, Oakley DA, Allen P, Dolan RJ (2005), “Anxiety reduction through detachment: subjective, physiological, and neural effects.” J Cogn Neurosci 17(6):874-83 Details
Seymour B, O'Doherty JP, Koltzenburg M, Wiech K, Frackowiak R, Friston K, Dolan R (2005), “Opponent appetitive-aversive neural processes underlie predictive learning of pain relief.” Nat Neurosci 8(9):1234-40 Details
Wiech K, Seymour B, Kalisch R, Stephan KE, Koltzenburg M, Driver J, Dolan RJ (2005), “Modulation of pain processing in hyperalgesia by cognitive demand.” Neuroimage 27(1):59-69 Details
Seymour B, O'Doherty JP, Dayan P, Koltzenburg M, Jones AK, Dolan RJ, Friston KJ, Frackowiak RS (2004), “Temporal difference models describe higher-order learning in humans.” Nature 429(6992):664-7 Details
Singer T, Seymour B, O'Doherty J, Kaube H, Dolan RJ, Frith CD (2004), “Empathy for pain involves the affective but not sensory components of pain.” Science 303(5661):1157-62 Details