Dr Brian Billups
Dr Brian Billups is pleased to consider applications from prospective PhD students.
My lab is interested in processes that modulate synaptic transmission. Using direct electrophysiological recordings from pre and postsynaptic cells in brain slices, combined with fluorescent ion imaging, we investigate release and recycling of neurotransmitter molecules.
No direct clinical relevance
Electrophysiological recording techniques
Whole cell patch clamp
No collaborators listed
Billups B (2005), “Colocalization of vesicular glutamate transporters in the rat superior olivary complex” Neuroscience Letters 382(1-2):66-70 Details
Billups B, Graham BP, Wong AY, Forsythe ID (2005), “Unmasking group III metabotropic glutamate autoreceptor function at excitatory synapses in the rat CNS” Journal of Physiology 565(Pt 3):885-96 Details
Billups B, Forsythe ID (2002), “ Presynaptic mitochondrial calcium sequestration influences transmission at mammalian central synapses” Journal of Neuroscience 22(14):5840-7
Barker M, Billups B, Hamann M (2009), “Focal macromolecule delivery in neuronal tissue using simultaneous pressure ejection and local electroporation.” J Neurosci Methods 177(2):273-84 Details
Blot A, Billups D, Bjørkmo M, Quazi AZ, Uwechue NM, Chaudhry FA, Billups B (2009), “Functional expression of two system A glutamine transporter isoforms in rat auditory brainstem neurons.” Neuroscience 164(3):998-1008 Details
Billups D, Billups B, Challiss RA, Nahorski SR (2006), “Modulation of Gq-protein-coupled inositol trisphosphate and Ca2+ signaling by the membrane potential.” J Neurosci 26(39):9983-95 Details