Dr Andrew Patton

Interests

Study of circadian rhythms in the mammalian suprachiasmatic nucleus (SCN) using genetic and electrophysiological approaches.

My primary research focuses on the role of GABAergic synaptic transmission within the SCN and how this contributes to the network-wide coherence of circadian rhythmicity.

Additional projects include the manipulation of organotypic SCN slices using pharmacology and optogenetic approaches.

Research Focus

Keywords

Circadian

Rhythm

SCN

Electrophysiology

Genetic Manipulation

Clinical conditions

Sleep disorders

Equipment

Electrophysiological recording techniques

Fluorescence microscopy

Whole cell patch clamp

Collaborators

No collaborators listed

Associated News Items


    Publications

    2011

    Nakamura Y, Wood CL, Patton AP, Jaafari N, Henley JM, Mellor JR, Hanley JG (2011), “PICK1 inhibition of the Arp2/3 complex controls dendritic spine size and synaptic plasticity.” EMBO J 30(4):719-30 Details